DE602006016651D1 - Zwischenprodukte und verfahren zur herstellung aromatischer derivate von 1-adamantan - Google Patents

Zwischenprodukte und verfahren zur herstellung aromatischer derivate von 1-adamantan

Info

Publication number
DE602006016651D1
DE602006016651D1 DE602006016651T DE602006016651T DE602006016651D1 DE 602006016651 D1 DE602006016651 D1 DE 602006016651D1 DE 602006016651 T DE602006016651 T DE 602006016651T DE 602006016651 T DE602006016651 T DE 602006016651T DE 602006016651 D1 DE602006016651 D1 DE 602006016651D1
Authority
DE
Germany
Prior art keywords
adamantane
aromatic derivatives
production
intermediate products
obtaining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006016651T
Other languages
English (en)
Inventor
Alexander Christian Comely
Sanchez Marta Marfil
Jane Llorenc Rafecas
Escale Antoni Riera
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Finorga SAS
Original Assignee
Finorga SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Finorga SAS filed Critical Finorga SAS
Publication of DE602006016651D1 publication Critical patent/DE602006016651D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/14—Preparation of carboxylic acid nitriles by reaction of cyanides with halogen-containing compounds with replacement of halogen atoms by cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE602006016651T 2005-12-02 2006-12-01 Zwischenprodukte und verfahren zur herstellung aromatischer derivate von 1-adamantan Active DE602006016651D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200503057 2005-12-02
PCT/IB2006/054548 WO2007063523A1 (en) 2005-12-02 2006-12-01 Intermediates and process for the preparation of aromatic derivatives of 1-adamantane

Publications (1)

Publication Number Publication Date
DE602006016651D1 true DE602006016651D1 (de) 2010-10-14

Family

ID=37908248

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006016651T Active DE602006016651D1 (de) 2005-12-02 2006-12-01 Zwischenprodukte und verfahren zur herstellung aromatischer derivate von 1-adamantan

Country Status (7)

Country Link
US (1) US20110040115A1 (de)
EP (1) EP1986985B1 (de)
JP (1) JP2009517457A (de)
AT (1) ATE479649T1 (de)
CA (1) CA2631698A1 (de)
DE (1) DE602006016651D1 (de)
WO (1) WO2007063523A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102015606B (zh) 2007-06-08 2015-02-04 满康德股份有限公司 IRE-1α抑制剂

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU85849A1 (fr) * 1985-04-11 1986-11-05 Cird Derives benzonaphtaleniques,leur procede de preparation et leur application dans les domaines pharmaceutiques et cosmetiques
US6462064B1 (en) * 1996-07-08 2002-10-08 Galderma Research & Development S.N.C. Apoptosis inducing adamantyl derivatives and their usage as anti-cancer agents, especially for cervical cancers and dysplasias
WO2005108338A1 (en) * 2004-05-03 2005-11-17 Auspex Pharmaceuticals Novel therapeutic agents for the treatment of cancer, metabolic diseases and skin disorders
ITMI20050550A1 (it) * 2005-04-01 2006-10-02 Dipharma Spa Procedimento per la preparazione di adapalene
JP5155148B2 (ja) * 2005-04-08 2013-02-27 ガルデルマ・リサーチ・アンド・デヴェロップメント ６−［３−（１−アダマンチル）−４−メトキシフェニル］−２−ナフトエ酸の合成方法
US7589239B2 (en) * 2005-09-02 2009-09-15 Auspex Pharmaceuticals Therapeutic agents for the treatment of cancer, metabolic diseases and skin disorders

Also Published As

Publication number Publication date
US20110040115A1 (en) 2011-02-17
EP1986985B1 (de) 2010-09-01
WO2007063523A1 (en) 2007-06-07
JP2009517457A (ja) 2009-04-30
ATE479649T1 (de) 2010-09-15
CA2631698A1 (en) 2007-06-07
EP1986985A1 (de) 2008-11-05

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