DE602005026692D1 - Verbesserte mevalonatkinase - Google Patents

Verbesserte mevalonatkinase

Info

Publication number
DE602005026692D1
DE602005026692D1 DE602005026692T DE602005026692T DE602005026692D1 DE 602005026692 D1 DE602005026692 D1 DE 602005026692D1 DE 602005026692 T DE602005026692 T DE 602005026692T DE 602005026692 T DE602005026692 T DE 602005026692T DE 602005026692 D1 DE602005026692 D1 DE 602005026692D1
Authority
DE
Germany
Prior art keywords
improved
mevalonate kinase
modified
vectors
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005026692T
Other languages
English (en)
Inventor
Renyuan Bai
Markus Wyss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35907004&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE602005026692(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of DE602005026692D1 publication Critical patent/DE602005026692D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE602005026692T 2004-12-14 2005-12-12 Verbesserte mevalonatkinase Active DE602005026692D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04029529 2004-12-14
PCT/EP2005/013282 WO2006063752A1 (en) 2004-12-14 2005-12-12 Improved mevalonate kinase

Publications (1)

Publication Number Publication Date
DE602005026692D1 true DE602005026692D1 (de) 2011-04-14

Family

ID=35907004

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005026692T Active DE602005026692D1 (de) 2004-12-14 2005-12-12 Verbesserte mevalonatkinase

Country Status (7)

Country Link
US (1) US8338155B2 (de)
EP (1) EP1824969B1 (de)
JP (1) JP4841562B2 (de)
CN (1) CN101080490B (de)
AT (1) ATE500321T1 (de)
DE (1) DE602005026692D1 (de)
WO (1) WO2006063752A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8257957B2 (en) 2006-09-26 2012-09-04 The Regents Of The University Of California Production of isoprenoids and isoprenoid precursors
JP2009000046A (ja) * 2007-06-21 2009-01-08 Hitachi Zosen Corp トチュウのメバロン酸経路の酵素をコードする遺伝子
CA2709107A1 (en) 2007-12-13 2009-06-18 Danisco Us Inc. Compositions and methods for producing isoprene
KR20110003367A (ko) 2008-04-14 2011-01-11 다우 코닝 코포레이션 붕소 가교결합된 오가노폴리실록산 에멀젼
MY153871A (en) 2008-04-23 2015-03-31 Danisco Us Inc Isoprene synthase variants for improved microbial production of isoprene
EP2334788A1 (de) 2008-09-15 2011-06-22 Danisco US Inc. Gesteigerte isoprenproduktion unter verwendung des unteren mevalonatwegs von archaea
CN102656265A (zh) 2009-04-23 2012-09-05 丹尼斯科美国公司 异戊二烯合酶的三维结构及其用于产生变体的用途
EP2336310A1 (de) 2009-12-16 2011-06-22 Isobionics B.V. Valencensynthase
BR122021005283B1 (pt) 2010-06-02 2022-02-22 Evolva, Inc Hospedeiro recombinante que compreende genes recombinantes para produção deesteviol ou glicosídeo de esteviol, método para produzir esteviol, glicosídeo de esteviol ou composição de glicosídeo de esteviol e método para sintetizar esteviol ou glicosídeo de esteviol
WO2012058494A2 (en) 2010-10-27 2012-05-03 Danisco Us Inc. Isoprene synthase variants for improved production of isoprene
EP2537926A1 (de) 2011-06-21 2012-12-26 Isobionics B.V. Valencensynthase
KR20200057799A (ko) 2011-08-08 2020-05-26 에볼바 에스아 스테비올 글리코시드의 재조합 생산
CN102392032A (zh) * 2011-11-28 2012-03-28 山东省农业科学院作物研究所 小麦甲羟戊酸激酶基因TaMVK及其分离克隆、酶活性测定方法
CN103205432B (zh) * 2012-01-11 2015-06-10 安徽医科大学第一附属医院 弥散型浅表性光线性汗孔角化症(dsap)相关基因
US9163263B2 (en) 2012-05-02 2015-10-20 The Goodyear Tire & Rubber Company Identification of isoprene synthase variants with improved properties for the production of isoprene
CA2899276C (en) 2013-02-06 2022-11-01 Evolva Sa Methods for improved production of rebaudioside d and rebaudioside m
EP2954061B1 (de) 2013-02-11 2023-11-22 Evolva SA Effiziente herstellung von steviolglycosiden in rekombinanten wirtszellen
RU2014112066A (ru) 2014-03-28 2015-10-10 Адзиномото Ко., Инк. Способ получения мономерного изопрена
CN106572688B (zh) 2014-08-11 2022-01-25 埃沃尔瓦公司 在重组宿主中生产甜菊醇糖苷
JP2017528134A (ja) 2014-09-09 2017-09-28 エヴォルヴァ エスアー．Ｅｖｏｌｖａ Ｓａ． 組み換え宿主におけるステビオールグリコシドの生産
WO2016120486A1 (en) 2015-01-30 2016-08-04 Evolva Sa Production of steviol glycosides in recombinant hosts
BR112017019625A2 (pt) 2015-03-16 2018-05-08 Dsm Ip Assets Bv udp-glicosiltransferases
WO2017025362A1 (en) 2015-08-07 2017-02-16 Evolva Sa Production of steviol glycosides in recombinant hosts
SG11201808856TA (en) 2016-04-13 2018-11-29 Evolva Sa Production of steviol glycosides in recombinant hosts
EP3458599A1 (de) 2016-05-16 2019-03-27 Evolva SA Herstellung von steviolglycosiden in rekombinanten wirten
US11396669B2 (en) 2016-11-07 2022-07-26 Evolva Sa Production of steviol glycosides in recombinant hosts
NL2018457B1 (en) 2017-03-02 2018-09-21 Isobionics B V Santalene Synthase
NL2019473B1 (en) 2017-09-01 2019-03-11 Isobionics B V Terpene Synthase producing patchoulol and elemol, and preferably also pogostol
CA3084263A1 (en) 2017-12-07 2019-06-13 Zymergen Inc. Engineered biosynthetic pathways for production of (6e)-8-hydroxygeraniol by fermentation
EP3728212A1 (de) 2017-12-21 2020-10-28 Zymergen Inc. Nepetalactol-oxidoreduktasen, nepetalactol-synthasen und nebalacton produzierende mikroben
CN113621631A (zh) * 2021-08-11 2021-11-09 昆明理工大学 一种甲羟戊酸激酶基因rkmk及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI250210B (en) 1998-05-06 2006-03-01 Dsm Ip Assets Bv An isolated DNA sequence coding for an enzyme involved in the mevalonate pathway or the pathway from isopentenyl pyrophosphate to farnesyl pyrophosphate
EP1095034A1 (de) 1998-07-06 2001-05-02 Eastman Chemical Company Darstellung von tocoferolen
US6410755B1 (en) 1998-07-06 2002-06-25 Dcv, Inc. Method of vitamin production
ATE405638T1 (de) 2001-06-06 2008-09-15 Dsm Ip Assets Bv Verbesserte isoprenoid herstellung
EP1592797A1 (de) * 2003-02-05 2005-11-09 Basf Aktiengesellschaft Mevalonat kinase als target fur fungizide
DE602004020218D1 (de) * 2003-06-12 2009-05-07 Dsm Ip Assets Bv Feedback resistante mevalonate kinase

Also Published As

Publication number Publication date
JP4841562B2 (ja) 2011-12-21
WO2006063752A1 (en) 2006-06-22
US20070286850A1 (en) 2007-12-13
CN101080490B (zh) 2012-08-15
ATE500321T1 (de) 2011-03-15
EP1824969B1 (de) 2011-03-02
CN101080490A (zh) 2007-11-28
JP2008522635A (ja) 2008-07-03
US8338155B2 (en) 2012-12-25
EP1824969A1 (de) 2007-08-29

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