DE602005025763D1 - Es-zellmutationsverfahren und -system - Google Patents

Es-zellmutationsverfahren und -system

Info

Publication number
DE602005025763D1
DE602005025763D1 DE602005025763T DE602005025763T DE602005025763D1 DE 602005025763 D1 DE602005025763 D1 DE 602005025763D1 DE 602005025763 T DE602005025763 T DE 602005025763T DE 602005025763 T DE602005025763 T DE 602005025763T DE 602005025763 D1 DE602005025763 D1 DE 602005025763D1
Authority
DE
Germany
Prior art keywords
mutation process
cell mutation
cell
mutation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005025763T
Other languages
English (en)
Inventor
Junji Takeda
Kosuke Yusa
Kyoji Horie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Osaka University NUC
Carna Biosciences Inc
Original Assignee
Osaka University NUC
Carna Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osaka University NUC, Carna Biosciences Inc filed Critical Osaka University NUC
Publication of DE602005025763D1 publication Critical patent/DE602005025763D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0306—Animal model for genetic diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE602005025763T 2004-06-08 2005-06-07 Es-zellmutationsverfahren und -system Active DE602005025763D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004170587 2004-06-08
PCT/JP2005/010436 WO2005121324A1 (ja) 2004-06-08 2005-06-07 Ｅｓ細胞の変異方法およびシステム

Publications (1)

Publication Number Publication Date
DE602005025763D1 true DE602005025763D1 (de) 2011-02-17

Family

ID=35503060

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005025763T Active DE602005025763D1 (de) 2004-06-08 2005-06-07 Es-zellmutationsverfahren und -system

Country Status (5)

Country Link
US (1) US20080318804A1 (de)
EP (1) EP1757682B1 (de)
JP (1) JP4732338B2 (de)
DE (1) DE602005025763D1 (de)
WO (1) WO2005121324A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7055469B2 (ja) * 2018-05-08 2022-04-18 国立大学法人大阪大学 ホモ接合型細胞の作製方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0999273B1 (de) * 1997-07-25 2006-11-22 Agene Research Institute, Co., Ltd. Menschliches recq4 gen, das für eine helikase kodiert
JPH11276173A (ja) * 1998-03-27 1999-10-12 Eijiin Kenkyusho:Kk ヘリカーゼをコードする遺伝子、ＲｅｃＱ５
AU6731300A (en) * 1999-10-05 2001-05-10 Agene Research Institute Co., Ltd. Nuclear localized recq5 type dna helicase
JP2004267001A (ja) * 2000-08-16 2004-09-30 Kansai Tlo Kk トランスジェニック哺乳動物及びその作製方法並びにこれを用いた遺伝子機能の解明方法
US20040072264A1 (en) * 2000-12-22 2004-04-15 Morris David W. Novel compositions and methods for cancer

Also Published As

Publication number Publication date
WO2005121324A1 (ja) 2005-12-22
EP1757682A4 (de) 2007-12-19
EP1757682A1 (de) 2007-02-28
JP4732338B2 (ja) 2011-07-27
US20080318804A1 (en) 2008-12-25
JPWO2005121324A1 (ja) 2008-04-10
EP1757682B1 (de) 2011-01-05

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