DE602005017131D1 - Verwendung von adefovir oder tenofovir zur hemmung von mmtv-artigen viren im zusammenhang mit brustkrebs und primärer biliärer zirrhose - Google Patents
Verwendung von adefovir oder tenofovir zur hemmung von mmtv-artigen viren im zusammenhang mit brustkrebs und primärer biliärer zirrhoseInfo
- Publication number
- DE602005017131D1 DE602005017131D1 DE602005017131T DE602005017131T DE602005017131D1 DE 602005017131 D1 DE602005017131 D1 DE 602005017131D1 DE 602005017131 T DE602005017131 T DE 602005017131T DE 602005017131 T DE602005017131 T DE 602005017131T DE 602005017131 D1 DE602005017131 D1 DE 602005017131D1
- Authority
- DE
- Germany
- Prior art keywords
- adefovir
- tenofovir
- breast cancer
- viruses
- connection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- WOZSCQDILHKSGG-UHFFFAOYSA-N adefovir depivoxil Chemical compound N1=CN=C2N(CCOCP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)C=NC2=C1N WOZSCQDILHKSGG-UHFFFAOYSA-N 0.000 title abstract 3
- 229960004556 tenofovir Drugs 0.000 title abstract 3
- 206010006187 Breast cancer Diseases 0.000 title abstract 2
- 208000026310 Breast neoplasm Diseases 0.000 title abstract 2
- 229960001997 adefovir Drugs 0.000 title abstract 2
- 230000002401 inhibitory effect Effects 0.000 title abstract 2
- 208000008439 Biliary Liver Cirrhosis Diseases 0.000 title 1
- 208000033222 Biliary cirrhosis primary Diseases 0.000 title 1
- 208000012654 Primary biliary cholangitis Diseases 0.000 title 1
- 241000700605 Viruses Species 0.000 title 1
- SGOIRFVFHAKUTI-ZCFIWIBFSA-N tenofovir (anhydrous) Chemical compound N1=CN=C2N(C[C@@H](C)OCP(O)(O)=O)C=NC2=C1N SGOIRFVFHAKUTI-ZCFIWIBFSA-N 0.000 title 1
- VCMJCVGFSROFHV-WZGZYPNHSA-N tenofovir disoproxil fumarate Chemical compound OC(=O)\C=C\C(O)=O.N1=CN=C2N(C[C@@H](C)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C)C=NC2=C1N VCMJCVGFSROFHV-WZGZYPNHSA-N 0.000 abstract 2
- MELHEUHXJKQZNC-UHFFFAOYSA-N 2-(6-aminopurin-9-yl)ethoxymethyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acid Chemical compound NC1=NC=NC2=C1N=CN2CCOCP(O)(=O)OP(O)(=O)OP(O)(O)=O MELHEUHXJKQZNC-UHFFFAOYSA-N 0.000 abstract 1
- 241000713333 Mouse mammary tumor virus Species 0.000 abstract 1
- IACQCQDWSIQSRP-ZCFIWIBFSA-N [(2r)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acid Chemical compound N1=CN=C2N(C[C@@H](C)OCP(O)(=O)OP(O)(=O)OP(O)(O)=O)C=NC2=C1N IACQCQDWSIQSRP-ZCFIWIBFSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 241001430294 unidentified retrovirus Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53806604P | 2004-01-21 | 2004-01-21 | |
| PCT/US2005/002043 WO2005072748A1 (en) | 2004-01-21 | 2005-01-21 | Use of adefovir or tenofovir for inhibiting mmtv-like viruses involved in breast cancer and primary biliary cirrhosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602005017131D1 true DE602005017131D1 (de) | 2009-11-26 |
Family
ID=34825960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602005017131T Expired - Lifetime DE602005017131D1 (de) | 2004-01-21 | 2005-01-21 | Verwendung von adefovir oder tenofovir zur hemmung von mmtv-artigen viren im zusammenhang mit brustkrebs und primärer biliärer zirrhose |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20070281911A1 (https=) |
| EP (1) | EP1732569B1 (https=) |
| JP (1) | JP2007518815A (https=) |
| AT (1) | ATE445404T1 (https=) |
| AU (1) | AU2005209256B2 (https=) |
| CA (1) | CA2553455A1 (https=) |
| DE (1) | DE602005017131D1 (https=) |
| ES (1) | ES2334149T3 (https=) |
| NZ (1) | NZ548532A (https=) |
| WO (1) | WO2005072748A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006114064A2 (en) * | 2005-04-25 | 2006-11-02 | Institute Of Organic Chemistry And Biochemistry Ofthe Academy Of Sciences Of The Czech Republic | Use of compounds to enhance processivity of telomerase |
| RU2301088C2 (ru) * | 2005-09-01 | 2007-06-20 | Ростовский научно-исследовательский онкологический институт МЗ РФ | Способ лечения рецидива рака молочной железы |
| EP2020996B1 (en) | 2006-05-16 | 2011-11-23 | Gilead Sciences, Inc. | Method and compositions for treating hematological malignancies |
| AU2010303628B2 (en) * | 2009-10-05 | 2015-07-09 | Ambergen, Inc. | A method for diagnosing primary biliary cirrhosis (PBC) using novel autoantigens |
| US20140031250A1 (en) | 2010-10-07 | 2014-01-30 | David Tsai Ting | Biomarkers of Cancer |
| EP4556010A3 (en) | 2011-11-30 | 2025-07-23 | Emory University | Jak inhibitors for use in the prevention or treatment of a viral disease caused by a coronaviridae |
| US10301624B2 (en) | 2014-06-25 | 2019-05-28 | The General Hospital Corporation | Targeting human satellite II (HSATII) |
| DK3236972T3 (en) | 2014-12-26 | 2021-10-04 | Univ Emory | Antivirale N4-hydroxycytidin-derivativer |
| GB201509431D0 (en) * | 2015-06-01 | 2015-07-15 | Equigerminal Sa | Antiviral composition |
| JP6804790B1 (ja) | 2017-12-07 | 2020-12-23 | エモリー ユニバーシティー | Ｎ４−ヒドロキシシチジンおよび誘導体ならびにそれらに関連する抗ウイルス用途 |
| KR102196711B1 (ko) * | 2018-08-30 | 2020-12-30 | 가톨릭대학교 산학협력단 | 테노포비르 디소프록실 푸마르산을 유효성분으로 함유하는, 간섬유증 예방 또는 치료용 약학적 조성물 |
| JP7663236B2 (ja) * | 2019-02-22 | 2025-04-16 | 一素 村田 | ｍＴＯＲ阻害剤 |
| EP3993873A4 (en) * | 2019-07-02 | 2023-09-20 | Virago Vax Inc. | SUPPRESSION OF BREAST TUMORS |
| US12029783B2 (en) | 2019-07-02 | 2024-07-09 | Virago Vax Inc. | Mammary tumor virus vaccine |
| US12016844B2 (en) | 2019-07-02 | 2024-06-25 | Virago Vax Inc. | Mammary tumor virus suppression |
| TW202400134A (zh) | 2022-03-15 | 2024-01-01 | 美商羅米醫療公司 | 用於治療疾病之化合物及方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1220948B1 (en) * | 1999-06-01 | 2008-05-14 | Alton Ochsner Medical Foundation | Identification of a novel retrovirus associated with primary biliary cirrhosis and autoimmune disorders |
| CA2369848C (en) * | 1999-06-30 | 2011-09-20 | Robert F. Garry | Human endogenous retrovirus in breast cancer |
| CZ304734B6 (cs) * | 2000-07-21 | 2014-09-10 | Gilead Sciences, Inc. | Způsob přípravy 9-[2-(fosfonomethoxy)propyl]adeninu a 9-[2-(fosfonomethoxy)ethyl]adeninu |
| NZ536328A (en) * | 2002-05-13 | 2007-11-30 | Metabasis Therapeutics Inc | Novel phosphonic acid based prodrugs of PMEA and its analogues |
-
2005
- 2005-01-21 EP EP05706024A patent/EP1732569B1/en not_active Expired - Lifetime
- 2005-01-21 ES ES05706024T patent/ES2334149T3/es not_active Expired - Lifetime
- 2005-01-21 US US10/586,627 patent/US20070281911A1/en not_active Abandoned
- 2005-01-21 US US11/040,929 patent/US20050239753A1/en not_active Abandoned
- 2005-01-21 NZ NZ548532A patent/NZ548532A/en unknown
- 2005-01-21 WO PCT/US2005/002043 patent/WO2005072748A1/en not_active Ceased
- 2005-01-21 DE DE602005017131T patent/DE602005017131D1/de not_active Expired - Lifetime
- 2005-01-21 AT AT05706024T patent/ATE445404T1/de not_active IP Right Cessation
- 2005-01-21 AU AU2005209256A patent/AU2005209256B2/en not_active Ceased
- 2005-01-21 CA CA002553455A patent/CA2553455A1/en not_active Abandoned
- 2005-01-21 JP JP2006551327A patent/JP2007518815A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20070281911A1 (en) | 2007-12-06 |
| EP1732569B1 (en) | 2009-10-14 |
| EP1732569A1 (en) | 2006-12-20 |
| HK1099228A1 (en) | 2007-08-10 |
| WO2005072748A1 (en) | 2005-08-11 |
| CA2553455A1 (en) | 2005-08-11 |
| AU2005209256A1 (en) | 2005-08-11 |
| ES2334149T3 (es) | 2010-03-05 |
| JP2007518815A (ja) | 2007-07-12 |
| AU2005209256B2 (en) | 2010-11-18 |
| NZ548532A (en) | 2009-09-25 |
| ATE445404T1 (de) | 2009-10-15 |
| US20050239753A1 (en) | 2005-10-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |