DE602004031946D1 - Das künstliche cpg single strand deoxidation-oligonukleotid und dessen antivirale anwendungen - Google Patents

Das künstliche cpg single strand deoxidation-oligonukleotid und dessen antivirale anwendungen

Info

Publication number
DE602004031946D1
DE602004031946D1 DE602004031946T DE602004031946T DE602004031946D1 DE 602004031946 D1 DE602004031946 D1 DE 602004031946D1 DE 602004031946 T DE602004031946 T DE 602004031946T DE 602004031946 T DE602004031946 T DE 602004031946T DE 602004031946 D1 DE602004031946 D1 DE 602004031946D1
Authority
DE
Germany
Prior art keywords
virus
odns
deoxidation
oligonucleotide
stranded
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004031946T
Other languages
English (en)
Inventor
Yongli Yu
Liying Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Changchun Huapu Biotechnology Co Ltd
Original Assignee
Changchun Huapu Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN 03146157 external-priority patent/CN1289520C/zh
Priority claimed from CNB031562248A external-priority patent/CN1304412C/zh
Application filed by Changchun Huapu Biotechnology Co Ltd filed Critical Changchun Huapu Biotechnology Co Ltd
Publication of DE602004031946D1 publication Critical patent/DE602004031946D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
DE602004031946T 2003-07-25 2004-07-26 Das künstliche cpg single strand deoxidation-oligonukleotid und dessen antivirale anwendungen Active DE602004031946D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN 03146157 CN1289520C (zh) 2003-07-25 2003-07-25 具有抗流感病毒的含CpG单链脱氧寡核苷酸
CNB031562248A CN1304412C (zh) 2003-09-05 2003-09-05 抗单股正链RNA病毒人工合成的含CpG单链脱氧寡核苷酸
PCT/CN2004/000863 WO2005014611A1 (fr) 2003-07-25 2004-07-26 Oligodesoxyribonucleotide a simple brin cpg artificiel et utilisations antivirales

Publications (1)

Publication Number Publication Date
DE602004031946D1 true DE602004031946D1 (de) 2011-05-05

Family

ID=34137222

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004031946T Active DE602004031946D1 (de) 2003-07-25 2004-07-26 Das künstliche cpg single strand deoxidation-oligonukleotid und dessen antivirale anwendungen

Country Status (8)

Country Link
US (1) US7491706B2 (de)
EP (2) EP2264046B1 (de)
JP (1) JP4809220B2 (de)
KR (1) KR101146203B1 (de)
AT (2) ATE502949T1 (de)
CA (1) CA2533434C (de)
DE (1) DE602004031946D1 (de)
WO (1) WO2005014611A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008521385A (ja) * 2004-11-29 2008-06-26 長春華普生物技術有限公司 アジュバントとしてのCpG含有一本鎖デオキシヌクレオチド
CN1865275B (zh) 2005-05-17 2011-06-15 长春华普生物技术有限公司 对人b细胞肿瘤有治疗作用的人工合成的单链脱氧核苷酸
PT2411521E (pt) 2009-03-25 2015-04-21 Univ Texas Composições para estimulação de resistência imunitária inata de mamíferos contra patogénicos
KR101452830B1 (ko) * 2012-04-06 2014-10-21 아이진 주식회사 두 가지 항암물질을 동시에 제공하는 대장균 균주
WO2016044839A2 (en) 2014-09-19 2016-03-24 The Board Of Regents Of The University Of Texas System Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds
WO2021249116A1 (en) 2020-06-10 2021-12-16 Sichuan Clover Biopharmaceuticals, Inc. Coronavirus vaccine compositions, methods, and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002510644A (ja) * 1998-04-03 2002-04-09 ユニバーシティ オブ アイオワ リサーチ ファウンデーション 免疫治療用オリゴヌクレオチドおよびサイトカインを用いる免疫系刺激のための方法および産物
US6977245B2 (en) * 1999-04-12 2005-12-20 The United States Of America As Represented By The Department Of Health And Human Services Oligodeoxynucleotide and its use to induce an immune response
CN1280303C (zh) * 2003-05-28 2006-10-18 长春华普生物技术有限公司 人工合成的含CpG单链脱氧寡核苷酸及其抗SARS病毒作用

Also Published As

Publication number Publication date
KR20060054354A (ko) 2006-05-22
JP2006528491A (ja) 2006-12-21
EP1650218A4 (de) 2008-07-02
EP2264046B1 (de) 2011-11-09
EP1650218B1 (de) 2011-03-23
EP2264046A1 (de) 2010-12-22
KR101146203B1 (ko) 2012-05-25
US7491706B2 (en) 2009-02-17
US20070155683A1 (en) 2007-07-05
CA2533434C (en) 2011-07-05
WO2005014611A1 (fr) 2005-02-17
JP4809220B2 (ja) 2011-11-09
ATE502949T1 (de) 2011-04-15
CA2533434A1 (en) 2005-02-17
EP1650218A1 (de) 2006-04-26
ATE532792T1 (de) 2011-11-15

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