DE602004027714D1 - Anti-tumor effekt von bik-mutanten - Google Patents
Anti-tumor effekt von bik-mutantenInfo
- Publication number
- DE602004027714D1 DE602004027714D1 DE602004027714T DE602004027714T DE602004027714D1 DE 602004027714 D1 DE602004027714 D1 DE 602004027714D1 DE 602004027714 T DE602004027714 T DE 602004027714T DE 602004027714 T DE602004027714 T DE 602004027714T DE 602004027714 D1 DE602004027714 D1 DE 602004027714D1
- Authority
- DE
- Germany
- Prior art keywords
- bik
- tumor effect
- administered
- polynucleotide
- cancer therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 238000011275 oncology therapy Methods 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 239000002502 liposome Substances 0.000 abstract 1
- 230000026731 phosphorylation Effects 0.000 abstract 1
- 238000006366 phosphorylation reaction Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 230000000861 pro-apoptotic effect Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Marine Sciences & Fisheries (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45990103P | 2003-04-02 | 2003-04-02 | |
PCT/US2004/010342 WO2004089981A2 (en) | 2003-04-02 | 2004-04-02 | Antitumor effect of mutant bik |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004027714D1 true DE602004027714D1 (de) | 2010-07-29 |
Family
ID=33159707
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004027714T Expired - Lifetime DE602004027714D1 (de) | 2003-04-02 | 2004-04-02 | Anti-tumor effekt von bik-mutanten |
Country Status (8)
Country | Link |
---|---|
US (3) | US20050118154A1 (de) |
EP (1) | EP1611153B1 (de) |
JP (1) | JP2007524380A (de) |
CN (1) | CN100497382C (de) |
AT (1) | ATE471337T1 (de) |
DE (1) | DE602004027714D1 (de) |
DK (1) | DK1611153T3 (de) |
WO (1) | WO2004089981A2 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007535315A (ja) | 2004-04-02 | 2007-12-06 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 癌特異的プロモーター |
CA2523032A1 (en) | 2005-10-07 | 2007-04-07 | Immunovaccine Technologies Inc. | Vaccines for cancer therapy |
US20090192101A1 (en) * | 2006-11-22 | 2009-07-30 | Mien-Chie Hung | Cancer-specific promoters |
US8642067B2 (en) | 2007-04-02 | 2014-02-04 | Allergen, Inc. | Methods and compositions for intraocular administration to treat ocular conditions |
CN101827613A (zh) | 2007-09-27 | 2010-09-08 | 免疫疫苗技术有限公司 | 在包括连续疏水相的载体中的脂质体在体内输送多核苷酸中的应用 |
US20100209452A1 (en) * | 2007-10-03 | 2010-08-19 | Immunovaccine Technologies, Inc | Compositions comprising an antigen, an amphipathic compound and a hydrophobic carrier, and uses thereof |
US8809392B2 (en) | 2008-03-28 | 2014-08-19 | Ecolab Usa Inc. | Sulfoperoxycarboxylic acids, their preparation and methods of use as bleaching and antimicrobial agents |
EP2296696B1 (de) * | 2008-06-05 | 2014-08-27 | ImmunoVaccine Technologies Inc. | Zusammensetzungen mit liposomen, einem antigen, einem polynucleotid und einem träger mit einer kontinuierlichen phase einer hydrophoben substanz |
AU2012321022B2 (en) | 2011-10-06 | 2017-03-23 | Immunovaccine Technologies Inc. | Liposome compositions comprising an adjuvant that activates or increases the activity of TLR2 and uses thereof |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4879236A (en) | 1984-05-16 | 1989-11-07 | The Texas A&M University System | Method for producing a recombinant baculovirus expression vector |
US4797368A (en) | 1985-03-15 | 1989-01-10 | The United States Of America As Represented By The Department Of Health And Human Services | Adeno-associated virus as eukaryotic expression vector |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
US5284760A (en) | 1989-04-03 | 1994-02-08 | Feinstone Stephen M | Techniques for producing site-directed mutagenesis of cloned DNA |
US5220007A (en) | 1990-02-15 | 1993-06-15 | The Worcester Foundation For Experimental Biology | Method of site-specific alteration of RNA and production of encoded polypeptides |
US5149797A (en) | 1990-02-15 | 1992-09-22 | The Worcester Foundation For Experimental Biology | Method of site-specific alteration of rna and production of encoded polypeptides |
US5670488A (en) | 1992-12-03 | 1997-09-23 | Genzyme Corporation | Adenovirus vector for gene therapy |
DE69112207T2 (de) | 1990-04-05 | 1996-03-28 | Roberto Crea | "walk-through"-mutagenese. |
US5641484A (en) | 1990-12-04 | 1997-06-24 | Board Of Regents, The University Of Texas System | Methods for the suppression of neu mediated tumors by adenoviral E1A and SV40 large T antigen |
WO1993013216A1 (en) | 1991-12-24 | 1993-07-08 | The President And Fellows Of Harvard College | Site-directed mutagenesis of dna |
US5389514A (en) | 1992-08-28 | 1995-02-14 | Fox Chase Cancer Center | Method for specifically altering the nucleotide sequence of RNA |
US6638762B1 (en) * | 1994-11-28 | 2003-10-28 | Genetic Therapy, Inc. | Tissue-vectors specific replication and gene expression |
US5789166A (en) | 1995-12-08 | 1998-08-04 | Stratagene | Circular site-directed mutagenesis |
AU9402898A (en) * | 1997-09-26 | 1999-04-23 | Washington University | Cell death agonists |
US6190912B1 (en) * | 1998-03-31 | 2001-02-20 | Thomas Jefferson University | Blk genes and uses thereof in apoptosis |
-
2004
- 2004-04-02 JP JP2006509677A patent/JP2007524380A/ja active Pending
- 2004-04-02 DK DK04749717.7T patent/DK1611153T3/da active
- 2004-04-02 US US10/816,698 patent/US20050118154A1/en not_active Abandoned
- 2004-04-02 CN CNB2004800092987A patent/CN100497382C/zh not_active Expired - Fee Related
- 2004-04-02 EP EP04749717A patent/EP1611153B1/de not_active Expired - Lifetime
- 2004-04-02 WO PCT/US2004/010342 patent/WO2004089981A2/en active Application Filing
- 2004-04-02 DE DE602004027714T patent/DE602004027714D1/de not_active Expired - Lifetime
- 2004-04-02 AT AT04749717T patent/ATE471337T1/de not_active IP Right Cessation
-
2008
- 2008-07-28 US US12/180,730 patent/US20090075885A1/en not_active Abandoned
-
2010
- 2010-07-02 US US12/829,651 patent/US8304526B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1611153B1 (de) | 2010-06-16 |
WO2004089981A3 (en) | 2005-01-20 |
WO2004089981A2 (en) | 2004-10-21 |
US20090075885A1 (en) | 2009-03-19 |
US8304526B2 (en) | 2012-11-06 |
ATE471337T1 (de) | 2010-07-15 |
US20110020431A1 (en) | 2011-01-27 |
US20050118154A1 (en) | 2005-06-02 |
DK1611153T3 (da) | 2010-10-18 |
EP1611153A2 (de) | 2006-01-04 |
CN1771259A (zh) | 2006-05-10 |
CN100497382C (zh) | 2009-06-10 |
JP2007524380A (ja) | 2007-08-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TW200612918A (en) | Lonidamine analogs | |
WO2004087068A3 (en) | Cxcr4 antagonists and methods of their use | |
DE60221234D1 (de) | Verwendung von füllstoffe als sättigungsmittel | |
DE60231439D1 (de) | Mitotische kinesinhemmer | |
BR9811956B1 (pt) | naftiridinonas e composição farmacêutica compreendendo as mesmas. | |
SI1663242T1 (sl) | 2,4-pirimidindiaminske spojine in uporabe kot antiproliferativna sredstva | |
MX349188B (es) | Sns - 595 y metodos para utilizar el mismo. | |
NO20055130L (no) | Aminocykloheksyleter-forbindelser og deres anvendelse | |
ATE443724T1 (de) | Antikrebs-antikörper mit reduzierter komplementfixierung | |
WO2003103581A3 (en) | COMPOSITIONS AND METHODS FOR LIVER GROWTH AND PROTECTION | |
DE60025812D1 (de) | Jak-3 hemmer zur behandlung von allergischen störungen | |
IL190796A0 (en) | Compositions and their uses for gene therapy of bone conditions | |
ATE471337T1 (de) | Anti-tumor effekt von bik-mutanten | |
NO20050640L (no) | Rutenium anticancer komplekser | |
DK1390371T3 (da) | Oxazolo- og furopyrimidiner samt deres anvendelse i lægemidler mod tumorer | |
DE60128701D1 (en) | Claudin polypeptide | |
ATE356810T1 (de) | Polysubstituted 6-phenylphenanthridines mit pde- iv hemmender wirkung | |
ATE294793T1 (de) | Phenantrhridin-n-oxides mit pde-iv hemmender wirkung | |
NO20053903D0 (no) | Nukleotidlipidesterderivater. | |
ATE315029T1 (de) | 6-arylphenanthridine mit pde-iv hemmender wirkung | |
DE60026046D1 (de) | 5-hydroxysapogenin derivate mit aktivität gegen demenz | |
IL149416A0 (en) | Human enzymes of the metalloprotease family | |
ATE411036T1 (de) | Verwendung von aplidine in der behandlung von pankreaskrebs | |
HK1074840A1 (en) | Novel dithiolopyrrolones with therapeutic activity | |
ZA98420B (en) | Use of pramipexole in the treatment of restless legs syndrome. |