DE602004027553D1 - Polymer mit miteinander verbundenen poren zur arzneistoffzufuhr und verfahren - Google Patents
Polymer mit miteinander verbundenen poren zur arzneistoffzufuhr und verfahrenInfo
- Publication number
- DE602004027553D1 DE602004027553D1 DE602004027553T DE602004027553T DE602004027553D1 DE 602004027553 D1 DE602004027553 D1 DE 602004027553D1 DE 602004027553 T DE602004027553 T DE 602004027553T DE 602004027553 T DE602004027553 T DE 602004027553T DE 602004027553 D1 DE602004027553 D1 DE 602004027553D1
- Authority
- DE
- Germany
- Prior art keywords
- polymer
- drug
- pores
- monomer
- connected pores
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2/00—Processes of polymerisation
- C08F2/12—Polymerisation in non-solvents
- C08F2/16—Aqueous medium
- C08F2/22—Emulsion polymerisation
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/12—Esters of monohydric alcohols or phenols
- C08F220/14—Methyl esters, e.g. methyl (meth)acrylate
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/20—Esters of polyhydric alcohols or phenols, e.g. 2-hydroxyethyl (meth)acrylate or glycerol mono-(meth)acrylate
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Polymers & Plastics (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Eyeglasses (AREA)
- Materials For Medical Uses (AREA)
- Polymerisation Methods In General (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/SG2004/000237 WO2006014138A1 (en) | 2004-08-03 | 2004-08-03 | Polymer having interconnected pores for drug delivery and method |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004027553D1 true DE602004027553D1 (de) | 2010-07-15 |
Family
ID=35787372
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004027553T Active DE602004027553D1 (de) | 2004-08-03 | 2004-08-03 | Polymer mit miteinander verbundenen poren zur arzneistoffzufuhr und verfahren |
Country Status (8)
Country | Link |
---|---|
US (1) | US20070154522A1 (de) |
EP (1) | EP1773893B1 (de) |
JP (1) | JP2008509240A (de) |
CN (1) | CN101018814B (de) |
AT (1) | ATE469924T1 (de) |
DE (1) | DE602004027553D1 (de) |
TW (1) | TWI284526B (de) |
WO (1) | WO2006014138A1 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1817003B1 (de) | 2004-10-29 | 2018-02-21 | The Regents of The University of California | Poröse silicium-micropartikeln zur verabreichung von wirkstoffen ins auge |
WO2008085556A2 (en) | 2006-09-12 | 2008-07-17 | University Of South Florida | Surfactant-free nanoparticles for drug delivery |
JP2010510347A (ja) * | 2006-11-17 | 2010-04-02 | エージェンシー フォー サイエンス, テクノロジー アンド リサーチ | 架橋性湿潤剤を有する多孔質ポリマー材料 |
WO2008074153A1 (en) | 2006-12-18 | 2008-06-26 | Electronic Dietary Foods Inc. | Device for delivery of a substance |
EP2178499B1 (de) | 2007-07-10 | 2023-11-22 | The Regents of the University of California | Materialien und verfahren zur abgabe von zusammensetzungen an ausgewählte geweberegionen |
WO2010005398A1 (en) * | 2008-07-09 | 2010-01-14 | Agency For Science, Technology And Research | Trapping glucose probe in pores of polymer |
WO2010068281A2 (en) | 2008-12-11 | 2010-06-17 | Massachusetts Institute Of Technology | Contact lens drug delivery device |
EP2408828A4 (de) | 2009-03-19 | 2013-10-09 | Agency Science Tech & Res | Bildung von copolymer aus bikontinuierlicher mikroemulsion, die monomere verschiedener hydrophilie umfasst |
JP5922024B2 (ja) * | 2009-10-27 | 2016-05-24 | エージェンシー フォー サイエンス, テクノロジー アンド リサーチ | 高速応答のフォトクロミックナノ構造コンタクトレンズ |
US9298019B2 (en) | 2010-05-04 | 2016-03-29 | Johnson & Johnson Vision Care, Inc. | Surface enhanced ophthalmic lens |
US20130142858A1 (en) | 2010-05-17 | 2013-06-06 | Aerie Pharmaceuticals, Inc. | Drug delivery devices for delivery of ocular therapeutic agents |
US9394369B2 (en) | 2011-01-03 | 2016-07-19 | The Regents Of The University Of California | Luminescent porous silicon nanoparticles for targeted delivery and immunization |
US10049275B2 (en) | 2012-05-25 | 2018-08-14 | Paragon Crt Company Llc | Multicomponent optical device for visual and audible translation and recognition |
US10712588B2 (en) | 2012-05-25 | 2020-07-14 | Paragon Crt Company Llc | Contact lens having a space |
WO2013176768A1 (en) | 2012-05-25 | 2013-11-28 | Crt Technology, Inc. | Multicomponent optical device having a space |
CA2990247C (en) | 2015-07-09 | 2023-10-03 | The Regents Of The University Of California | Fusogenic liposome-coated porous silicon nanoparticles |
TW202009013A (zh) * | 2018-08-14 | 2020-03-01 | 優你康光學股份有限公司 | 具有功能性成分的隱形眼鏡及其產品 |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4741351A (en) * | 1985-03-07 | 1988-05-03 | The Modern Auto Recycling Techniques Corporation | Parts washer |
US5244799A (en) * | 1987-05-20 | 1993-09-14 | Anderson David M | Preparation of a polymeric hydrogel containing micropores and macropores for use as a cell culture substrate |
US4962178A (en) * | 1988-11-03 | 1990-10-09 | Ciba-Geigy Corporation | Novel polysiloxane-polyurethanes and contact lens thereof |
GB9006726D0 (en) * | 1990-03-26 | 1990-05-23 | Ici Plc | Micro-emulsions |
US5670557A (en) * | 1994-01-28 | 1997-09-23 | Minnesota Mining And Manufacturing Company | Polymerized microemulsion pressure sensitive adhesive compositions and methods of preparing and using same |
JP3640996B2 (ja) * | 1994-01-28 | 2005-04-20 | ミネソタ マイニング アンド マニュファクチャリング カンパニー | 高分子複合材料 |
US5840338A (en) * | 1994-07-18 | 1998-11-24 | Roos; Eric J. | Loading of biologically active solutes into polymer gels |
MX9707594A (es) * | 1995-04-04 | 1997-12-31 | Novartis Ag | Polimero de sustrato de crecimiento celular. |
AU716443B2 (en) * | 1996-03-27 | 2000-02-24 | Biocure, Inc. | Process for manufacture of a porous polymer by use of a porogen |
BR9708363A (pt) * | 1996-03-27 | 1999-08-03 | Novartis Ag | Polimero poroso com alto teor de água |
CA2248162A1 (en) * | 1996-04-04 | 1997-10-02 | Novartis Ag | Process for manufacture of a porous polymer from a mixture |
EP0907889B1 (de) * | 1996-04-25 | 2007-07-04 | BioArray Solutions Ltd. | Licht-regulierte, elektrokinetische zusammensetzung von partikeln an oberflächen |
KR0181252B1 (ko) * | 1996-12-31 | 1999-03-20 | 박원훈 | 에멀젼 방법에 의한 다공성 매트릭스형 서방성 제제의 제조방법 |
JPH10339857A (ja) * | 1997-06-05 | 1998-12-22 | Menicon Co Ltd | 薬剤徐放性コンタクトレンズの製法およびそれによってえられた薬剤徐放性コンタクトレンズ |
US6652581B1 (en) * | 1998-07-07 | 2003-11-25 | Boston Scientific Scimed, Inc. | Medical device with porous surface for controlled drug release and method of making the same |
US6039913A (en) * | 1998-08-27 | 2000-03-21 | Novartis Ag | Process for the manufacture of an ophthalmic molding |
US6284192B1 (en) * | 1998-11-02 | 2001-09-04 | Corning Incorporated | Extruding electrode material |
GB9902652D0 (en) * | 1999-02-05 | 1999-03-31 | Fermentech Med Ltd | Process |
US6715874B1 (en) * | 1999-02-08 | 2004-04-06 | Novartis Ag | Organic polymers |
US6410045B1 (en) * | 1999-02-22 | 2002-06-25 | Clyde Lewis Schultz | Drug delivery system for antiglaucomatous medication |
IT1306123B1 (it) * | 1999-04-02 | 2001-05-30 | Technopharma Sa | Soluzione oftalmica viscosizzata con azione detergente sulle lenti acontatto. |
JP3591827B2 (ja) * | 2000-08-11 | 2004-11-24 | 株式会社東芝 | 微細構造を有する成形体の製造方法 |
US6713081B2 (en) * | 2001-03-15 | 2004-03-30 | The United States Of America As Represented By The Department Of Health And Human Services | Ocular therapeutic agent delivery devices and methods for making and using such devices |
US6815074B2 (en) * | 2001-05-30 | 2004-11-09 | Novartis Ag | Polymeric materials for making contact lenses |
JP4184652B2 (ja) * | 2001-11-27 | 2008-11-19 | タキロン株式会社 | 有機−無機複合多孔体及びその製造方法 |
JP4448441B2 (ja) * | 2002-06-05 | 2010-04-07 | ユニヴァーシティ オブ フロリダ リサーチ ファウンデーション,インコーポレイテッド | 眼科用医薬のデリバリーシステム |
US8394366B2 (en) * | 2003-07-18 | 2013-03-12 | Agency For Science, Technology And Research | Thermosensitive polymers for therapeutic use and methods of preparation |
-
2004
- 2004-08-03 WO PCT/SG2004/000237 patent/WO2006014138A1/en active Application Filing
- 2004-08-03 JP JP2007524769A patent/JP2008509240A/ja not_active Ceased
- 2004-08-03 CN CN2004800432974A patent/CN101018814B/zh not_active Expired - Fee Related
- 2004-08-03 AT AT04749259T patent/ATE469924T1/de not_active IP Right Cessation
- 2004-08-03 EP EP04749259A patent/EP1773893B1/de not_active Not-in-force
- 2004-08-03 DE DE602004027553T patent/DE602004027553D1/de active Active
- 2004-08-04 US US10/585,259 patent/US20070154522A1/en not_active Abandoned
-
2005
- 2005-07-25 TW TW094125146A patent/TWI284526B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US20070154522A1 (en) | 2007-07-05 |
EP1773893A1 (de) | 2007-04-18 |
EP1773893B1 (de) | 2010-06-02 |
TWI284526B (en) | 2007-08-01 |
JP2008509240A (ja) | 2008-03-27 |
ATE469924T1 (de) | 2010-06-15 |
CN101018814B (zh) | 2011-05-04 |
EP1773893A4 (de) | 2008-02-27 |
CN101018814A (zh) | 2007-08-15 |
WO2006014138A1 (en) | 2006-02-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE602004027553D1 (de) | Polymer mit miteinander verbundenen poren zur arzneistoffzufuhr und verfahren | |
Aversa et al. | Physiologic human fluids and swelling behavior of hydrophilic biocompatible hybrid ceramo-polymeric materials | |
Mishra et al. | Time-dependent wetting behavior of PDMS surfaces with bioinspired, hierarchical structures | |
Calvert | Hydrogels for soft machines | |
CA2602905A1 (en) | Photocrosslinkable oligo(poly (ethylene glycol) fumarate) hydrogels for cell and drug delivery | |
DE60230537D1 (de) | Auf aromaten basierende silylmonomere mit hohem brechungsindex | |
ATE308570T1 (de) | Hydrogele | |
NO20072318L (no) | Okular levering av polymere leveringsformuleringer | |
ATE521656T1 (de) | Hydrophile, arylsiloxy-haltige makromonomere und polymere mit hohem brechungsindex sowie ophthalmische vorrichtungen mit solchen polymeren | |
DE602005015704D1 (de) | Flüssige dispersionspolymerzusammensetzungen, ihre herstellung und ihre verwendung | |
AU2002247154A1 (en) | Biocompatible fleece for hemostasis and tissue engineering | |
WO2005057272A3 (en) | Improved ocular lens | |
ATE396194T1 (de) | Monofunktionelle aromatische siloxan- makromonomere mit hohem brechungsindex | |
ES2137252T3 (es) | Biosensores que comprenden membranas de copolimeros acrilicos. | |
DK1077952T3 (da) | Polymeriserbare hydrofile monomerer, der absorberer ultraviolet lys | |
Fu et al. | Tough and highly efficient underwater self‐repairing hydrogels for soft electronics | |
Moreno et al. | Effect of different disinfectants on the microhardness and roughness of acrylic resins for ocular prosthesis | |
Nalampang et al. | Structural effects in photopolymerized sodium AMPS hydrogels crosslinked with poly (ethylene glycol) diacrylate for use as burn dressings | |
DE602004014537D1 (de) | Neue präpolymere zur verbesserten oberflächenmodifikation von kontaktlinsen | |
EA201100494A1 (ru) | Криогели из сополимера винилового спирта, сополимеры винилового спирта и способы их получения и продукты из них | |
CN108366960A (zh) | 药物递送装置 | |
DE602007012653D1 (de) | Siloxanvorpolymer mit hängenden kationischen und polymerisierbaren gruppen | |
Şarkaya et al. | Investigation of tribological properties of HEMA-based cryogels as potential articular cartilage biomaterials | |
CA2532493A1 (en) | Tissue substitute material | |
DE602004022384D1 (de) | Injizierbare gelbildende zusammensetzungenauf basis von vernetzten und unvernetzten polymeren und ihre verwendung |