DE602004027553D1 - Polymer mit miteinander verbundenen poren zur arzneistoffzufuhr und verfahren - Google Patents

Polymer mit miteinander verbundenen poren zur arzneistoffzufuhr und verfahren

Info

Publication number
DE602004027553D1
DE602004027553D1 DE602004027553T DE602004027553T DE602004027553D1 DE 602004027553 D1 DE602004027553 D1 DE 602004027553D1 DE 602004027553 T DE602004027553 T DE 602004027553T DE 602004027553 T DE602004027553 T DE 602004027553T DE 602004027553 D1 DE602004027553 D1 DE 602004027553D1
Authority
DE
Germany
Prior art keywords
polymer
drug
pores
monomer
connected pores
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004027553T
Other languages
English (en)
Inventor
Pei Yong Edwin Chow
Yi Yan Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agency for Science Technology and Research Singapore
Original Assignee
Agency for Science Technology and Research Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency for Science Technology and Research Singapore filed Critical Agency for Science Technology and Research Singapore
Publication of DE602004027553D1 publication Critical patent/DE602004027553D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts, ocular implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00Processes of polymerisation
    • C08F2/12Polymerisation in non-solvents
    • C08F2/16Aqueous medium
    • C08F2/22Emulsion polymerisation
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10Esters
    • C08F220/12Esters of monohydric alcohols or phenols
    • C08F220/14Methyl esters, e.g. methyl (meth)acrylate
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10Esters
    • C08F220/20Esters of polyhydric alcohols or phenols, e.g. 2-hydroxyethyl (meth)acrylate or glycerol mono-(meth)acrylate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Eyeglasses (AREA)
  • Materials For Medical Uses (AREA)
  • Polymerisation Methods In General (AREA)
DE602004027553T 2004-08-03 2004-08-03 Polymer mit miteinander verbundenen poren zur arzneistoffzufuhr und verfahren Active DE602004027553D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/SG2004/000237 WO2006014138A1 (en) 2004-08-03 2004-08-03 Polymer having interconnected pores for drug delivery and method

Publications (1)

Publication Number Publication Date
DE602004027553D1 true DE602004027553D1 (de) 2010-07-15

Family

ID=35787372

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004027553T Active DE602004027553D1 (de) 2004-08-03 2004-08-03 Polymer mit miteinander verbundenen poren zur arzneistoffzufuhr und verfahren

Country Status (8)

Country Link
US (1) US20070154522A1 (de)
EP (1) EP1773893B1 (de)
JP (1) JP2008509240A (de)
CN (1) CN101018814B (de)
AT (1) ATE469924T1 (de)
DE (1) DE602004027553D1 (de)
TW (1) TWI284526B (de)
WO (1) WO2006014138A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1817003B1 (de) 2004-10-29 2018-02-21 The Regents of The University of California Poröse silicium-micropartikeln zur verabreichung von wirkstoffen ins auge
WO2008085556A2 (en) 2006-09-12 2008-07-17 University Of South Florida Surfactant-free nanoparticles for drug delivery
JP2010510347A (ja) * 2006-11-17 2010-04-02 エージェンシー フォー サイエンス, テクノロジー アンド リサーチ 架橋性湿潤剤を有する多孔質ポリマー材料
WO2008074153A1 (en) 2006-12-18 2008-06-26 Electronic Dietary Foods Inc. Device for delivery of a substance
EP2178499B1 (de) 2007-07-10 2023-11-22 The Regents of the University of California Materialien und verfahren zur abgabe von zusammensetzungen an ausgewählte geweberegionen
WO2010005398A1 (en) * 2008-07-09 2010-01-14 Agency For Science, Technology And Research Trapping glucose probe in pores of polymer
WO2010068281A2 (en) 2008-12-11 2010-06-17 Massachusetts Institute Of Technology Contact lens drug delivery device
EP2408828A4 (de) 2009-03-19 2013-10-09 Agency Science Tech & Res Bildung von copolymer aus bikontinuierlicher mikroemulsion, die monomere verschiedener hydrophilie umfasst
JP5922024B2 (ja) * 2009-10-27 2016-05-24 エージェンシー フォー サイエンス, テクノロジー アンド リサーチ 高速応答のフォトクロミックナノ構造コンタクトレンズ
US9298019B2 (en) 2010-05-04 2016-03-29 Johnson & Johnson Vision Care, Inc. Surface enhanced ophthalmic lens
US20130142858A1 (en) 2010-05-17 2013-06-06 Aerie Pharmaceuticals, Inc. Drug delivery devices for delivery of ocular therapeutic agents
US9394369B2 (en) 2011-01-03 2016-07-19 The Regents Of The University Of California Luminescent porous silicon nanoparticles for targeted delivery and immunization
US10049275B2 (en) 2012-05-25 2018-08-14 Paragon Crt Company Llc Multicomponent optical device for visual and audible translation and recognition
US10712588B2 (en) 2012-05-25 2020-07-14 Paragon Crt Company Llc Contact lens having a space
WO2013176768A1 (en) 2012-05-25 2013-11-28 Crt Technology, Inc. Multicomponent optical device having a space
CA2990247C (en) 2015-07-09 2023-10-03 The Regents Of The University Of California Fusogenic liposome-coated porous silicon nanoparticles
TW202009013A (zh) * 2018-08-14 2020-03-01 優你康光學股份有限公司 具有功能性成分的隱形眼鏡及其產品

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US4741351A (en) * 1985-03-07 1988-05-03 The Modern Auto Recycling Techniques Corporation Parts washer
US5244799A (en) * 1987-05-20 1993-09-14 Anderson David M Preparation of a polymeric hydrogel containing micropores and macropores for use as a cell culture substrate
US4962178A (en) * 1988-11-03 1990-10-09 Ciba-Geigy Corporation Novel polysiloxane-polyurethanes and contact lens thereof
GB9006726D0 (en) * 1990-03-26 1990-05-23 Ici Plc Micro-emulsions
US5670557A (en) * 1994-01-28 1997-09-23 Minnesota Mining And Manufacturing Company Polymerized microemulsion pressure sensitive adhesive compositions and methods of preparing and using same
JP3640996B2 (ja) * 1994-01-28 2005-04-20 ミネソタ マイニング アンド マニュファクチャリング カンパニー 高分子複合材料
US5840338A (en) * 1994-07-18 1998-11-24 Roos; Eric J. Loading of biologically active solutes into polymer gels
MX9707594A (es) * 1995-04-04 1997-12-31 Novartis Ag Polimero de sustrato de crecimiento celular.
AU716443B2 (en) * 1996-03-27 2000-02-24 Biocure, Inc. Process for manufacture of a porous polymer by use of a porogen
BR9708363A (pt) * 1996-03-27 1999-08-03 Novartis Ag Polimero poroso com alto teor de água
CA2248162A1 (en) * 1996-04-04 1997-10-02 Novartis Ag Process for manufacture of a porous polymer from a mixture
EP0907889B1 (de) * 1996-04-25 2007-07-04 BioArray Solutions Ltd. Licht-regulierte, elektrokinetische zusammensetzung von partikeln an oberflächen
KR0181252B1 (ko) * 1996-12-31 1999-03-20 박원훈 에멀젼 방법에 의한 다공성 매트릭스형 서방성 제제의 제조방법
JPH10339857A (ja) * 1997-06-05 1998-12-22 Menicon Co Ltd 薬剤徐放性コンタクトレンズの製法およびそれによってえられた薬剤徐放性コンタクトレンズ
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US6713081B2 (en) * 2001-03-15 2004-03-30 The United States Of America As Represented By The Department Of Health And Human Services Ocular therapeutic agent delivery devices and methods for making and using such devices
US6815074B2 (en) * 2001-05-30 2004-11-09 Novartis Ag Polymeric materials for making contact lenses
JP4184652B2 (ja) * 2001-11-27 2008-11-19 タキロン株式会社 有機−無機複合多孔体及びその製造方法
JP4448441B2 (ja) * 2002-06-05 2010-04-07 ユニヴァーシティ オブ フロリダ リサーチ ファウンデーション,インコーポレイテッド 眼科用医薬のデリバリーシステム
US8394366B2 (en) * 2003-07-18 2013-03-12 Agency For Science, Technology And Research Thermosensitive polymers for therapeutic use and methods of preparation

Also Published As

Publication number Publication date
US20070154522A1 (en) 2007-07-05
EP1773893A1 (de) 2007-04-18
EP1773893B1 (de) 2010-06-02
TWI284526B (en) 2007-08-01
JP2008509240A (ja) 2008-03-27
ATE469924T1 (de) 2010-06-15
CN101018814B (zh) 2011-05-04
EP1773893A4 (de) 2008-02-27
CN101018814A (zh) 2007-08-15
WO2006014138A1 (en) 2006-02-09

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