DE602004027014D1 - Ttel und synergistischer kombinationen - Google Patents
Ttel und synergistischer kombinationenInfo
- Publication number
- DE602004027014D1 DE602004027014D1 DE602004027014T DE602004027014T DE602004027014D1 DE 602004027014 D1 DE602004027014 D1 DE 602004027014D1 DE 602004027014 T DE602004027014 T DE 602004027014T DE 602004027014 T DE602004027014 T DE 602004027014T DE 602004027014 D1 DE602004027014 D1 DE 602004027014D1
- Authority
- DE
- Germany
- Prior art keywords
- synergistic combinations
- ttel
- pathway
- experimental strategy
- novel experimental
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000011885 synergistic combination Substances 0.000 title abstract 3
- 239000013543 active substance Substances 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 238000012203 high throughput assay Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/06—Methods of screening libraries by measuring effects on living organisms, tissues or cells
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
- G16C20/30—Prediction of properties of chemical compounds, compositions or mixtures
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Computing Systems (AREA)
- Theoretical Computer Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Paper (AREA)
- Threshing Machine Elements (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45785903P | 2003-03-26 | 2003-03-26 | |
US45786003P | 2003-03-26 | 2003-03-26 | |
US45786103P | 2003-03-26 | 2003-03-26 | |
US48356403P | 2003-06-28 | 2003-06-28 | |
PCT/US2004/008957 WO2004088272A2 (en) | 2003-03-26 | 2004-03-24 | Methods to identify biologically active agents and synergistic combinations |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004027014D1 true DE602004027014D1 (de) | 2010-06-17 |
Family
ID=33136181
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004027014T Expired - Lifetime DE602004027014D1 (de) | 2003-03-26 | 2004-03-24 | Ttel und synergistischer kombinationen |
Country Status (6)
Country | Link |
---|---|
US (2) | US7264933B2 (de) |
EP (1) | EP1606759B1 (de) |
AT (1) | ATE467123T1 (de) |
DE (1) | DE602004027014D1 (de) |
ES (1) | ES2343411T3 (de) |
WO (1) | WO2004088272A2 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2672408C (en) * | 2007-03-30 | 2019-07-23 | 9898 Limited | Pharmacokinetic and pharmacodynamic modelling and methods for the development of phytocompositions or other multi-component compositions |
WO2012040313A1 (en) * | 2010-09-21 | 2012-03-29 | Lankenau Institute Of Medical Research Chemical Genomics Center | Ultra-high throughput screening methods to detect synergistic drug interactions |
EP3044712A4 (de) * | 2013-08-23 | 2017-12-13 | Elwha, Llc | Modifizierung eines kosmetikprodukts auf basis eines mikrobenprofils |
CN105224799B (zh) * | 2015-09-30 | 2018-03-02 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 联用药药效的处理方法和处理装置 |
CN109115742A (zh) * | 2018-09-05 | 2019-01-01 | 中国农业科学院农业质量标准与检测技术研究所 | 一种抗雄激素效应的检测方法 |
DE102020202529A1 (de) * | 2020-02-27 | 2021-09-02 | Robert Bosch Gesellschaft mit beschränkter Haftung | Verfahren zur Identifikation einer Wirkstoffkombination |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8928634D0 (en) | 1989-12-19 | 1990-02-21 | Unilever Plc | Method of testing |
US6780596B2 (en) * | 1998-09-17 | 2004-08-24 | Ashni Naturaceuticals, Inc. | Methods for determining the activity of complex mixtures |
AU2001268264A1 (en) * | 2000-06-20 | 2002-01-02 | Ortho-Mcneil Pharmaceutical, Inc. | Resazurin-based cytotoxicity assay |
CZ20024220A3 (cs) | 2000-06-30 | 2003-06-18 | Unilever N. V. | Prostředek pro péči o pleť |
US20020019010A1 (en) | 2000-07-07 | 2002-02-14 | Stockwell Brent R. | Methods for identifying combinations of entities as therapeutics |
US6569853B1 (en) * | 2000-11-06 | 2003-05-27 | Combinatorx, Incorporated | Combinations of chlorpromazine and pentamidine for the treatment of neoplastic disorders |
US6693125B2 (en) * | 2001-01-24 | 2004-02-17 | Combinatorx Incorporated | Combinations of drugs (e.g., a benzimidazole and pentamidine) for the treatment of neoplastic disorders |
WO2002061073A2 (en) * | 2001-01-30 | 2002-08-08 | Thomas Jefferson University | Mutwnt fish for genetic screebibg of lipid and cholesterol metabolism |
KR20040026680A (ko) | 2001-07-09 | 2004-03-31 | 콤비네이토릭스, 인코포레이티드 | 염증 질환 치료용 조합 |
TW573125B (en) | 2001-08-29 | 2004-01-21 | Combinatorx Inc | A screening system for identifying drug-drug interactions and methods of use thereof |
EP1448205B1 (de) | 2001-10-05 | 2011-03-23 | Zalicus Inc. | Kombinationen für die behandlung von immun-entzündlichen erkrankungen |
-
2004
- 2004-03-24 WO PCT/US2004/008957 patent/WO2004088272A2/en active Application Filing
- 2004-03-24 ES ES04758254T patent/ES2343411T3/es not_active Expired - Lifetime
- 2004-03-24 DE DE602004027014T patent/DE602004027014D1/de not_active Expired - Lifetime
- 2004-03-24 AT AT04758254T patent/ATE467123T1/de not_active IP Right Cessation
- 2004-03-24 US US10/807,811 patent/US7264933B2/en not_active Expired - Fee Related
- 2004-03-24 EP EP04758254A patent/EP1606759B1/de not_active Expired - Lifetime
-
2007
- 2007-08-17 US US11/893,401 patent/US20080026400A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1606759A2 (de) | 2005-12-21 |
WO2004088272A3 (en) | 2005-08-18 |
US20080026400A1 (en) | 2008-01-31 |
WO2004088272A2 (en) | 2004-10-14 |
EP1606759A4 (de) | 2007-11-28 |
ATE467123T1 (de) | 2010-05-15 |
US7264933B2 (en) | 2007-09-04 |
EP1606759B1 (de) | 2010-05-05 |
ES2343411T3 (es) | 2010-07-30 |
US20040203043A1 (en) | 2004-10-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EA200702568A1 (ru) | Гетеробициклические ингибиторы металлопротеазы и их применение | |
NO20100145L (no) | Forbindelser med serin-protease-inhiberende virkning, spesielt hepatitt C-NS3-inhiberende virkning | |
DE60327148D1 (de) | Schnelle thermische Behandlung von schweren Kohlenwasserstoffeinsätzen in Anwesenheit von Kalziumverbindungen | |
ECSP055708A (es) | Sales bencenosulfonato de derivadosde 4-fluoro-2-cianopirrolidina | |
CR9761A (es) | Reduccion de celulas b utilizando moleculas de union especificas cd37 y cd20 | |
DE60325567D1 (de) | Matrix für die modifizierte freigabe von aktiven substanzen | |
DE60330541D1 (de) | System zum Verfolgen von Poststücken | |
DE60023266D1 (de) | Serinprotease-inhibitoren | |
DE60329983D1 (de) | Wachsestersynthase-dna-sequenz, protein und verwendungen davon | |
BRPI0600777A (pt) | método e sistema para a criação, armazenamento, gerenciamento e consumo de dados especìficos de cultura | |
NL1023157A1 (nl) | Stabilisatormengsels. | |
EA200800357A1 (ru) | Новые фармацевтические соединения | |
ATE267396T1 (de) | Identifizierung von zellen während kinetischer versuchsreihen | |
ATE555119T1 (de) | Expression von proteaseinhibitoren und varianten davon in filamentösen pilzen | |
RS50671B (sr) | Kristalisan polietilen tereftalat, koji sadrži silicijum, i postupak za njegovo dobijanje | |
ATE475961T1 (de) | Kennzeichnungsschildersatz | |
DE602004027014D1 (de) | Ttel und synergistischer kombinationen | |
BRPI0411988A (pt) | substrato para admissão e crioconservação de uma multiplicidade de amostras, respectivos empregos e processo de crioconservação de amostra de substrato | |
NL1030253A1 (nl) | Elektronenmicroscoop. | |
EA200401032A1 (ru) | Антиинфарктные молекулы | |
JP2013017402A5 (de) | ||
DE10290563D2 (de) | Mittel zur Hemmung von Tumorzellen | |
NO20044186L (no) | Peptid-deformylaseinhibitorer | |
ITPR20030089A1 (it) | Valvola di omogeneizzazione. | |
DE50308413D1 (de) | Kontaktierung von nanoröhren |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |