DE602004024540D1 - Zusammensetzungen und Methoden zur Bestimmung des - Google Patents

Zusammensetzungen und Methoden zur Bestimmung des

Info

Publication number
DE602004024540D1
DE602004024540D1 DE602004024540T DE602004024540T DE602004024540D1 DE 602004024540 D1 DE602004024540 D1 DE 602004024540D1 DE 602004024540 T DE602004024540 T DE 602004024540T DE 602004024540 T DE602004024540 T DE 602004024540T DE 602004024540 D1 DE602004024540 D1 DE 602004024540D1
Authority
DE
Germany
Prior art keywords
determination
msi
compositions
methods
length
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004024540T
Other languages
English (en)
Inventor
Peter Dr Findeisen
Sabine Merx
Matthias Dr Kloor
Knebel Doeberitz Magnus Dr Von
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche MTM Laboratories AG
Original Assignee
Roche MTM Laboratories AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche MTM Laboratories AG filed Critical Roche MTM Laboratories AG
Publication of DE602004024540D1 publication Critical patent/DE602004024540D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE602004024540T 2004-10-19 2004-10-19 Zusammensetzungen und Methoden zur Bestimmung des Active DE602004024540D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04105159A EP1650311B1 (de) 2004-10-19 2004-10-19 Zusammensetzungen und Methoden zur Bestimmung des Mikrosatelliten Instabilitäts (MSI) Status

Publications (1)

Publication Number Publication Date
DE602004024540D1 true DE602004024540D1 (de) 2010-01-21

Family

ID=34929729

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004024540T Active DE602004024540D1 (de) 2004-10-19 2004-10-19 Zusammensetzungen und Methoden zur Bestimmung des

Country Status (6)

Country Link
US (1) US7662595B2 (de)
EP (1) EP1650311B1 (de)
AT (1) ATE451476T1 (de)
DE (1) DE602004024540D1 (de)
ES (1) ES2337573T3 (de)
WO (1) WO2006042854A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120295267A1 (en) * 2011-05-16 2012-11-22 Baylor Research Institute Detecting DNA Mismatch Repair-Deficient Colorectal Cancers
GB2497510A (en) * 2011-11-10 2013-06-19 Harry Cuppens Methods for determining mononucleotide sequence repeats
US11473126B2 (en) * 2017-03-24 2022-10-18 Seasunbio Materials Method for analyzing melting curve using bi-functional PNA probe, method for diagnosing microsatellite instability using the same, and kit for diagnosing microsatellite instability
CN110800061A (zh) * 2017-11-16 2020-02-14 伊鲁米那股份有限公司 用于确定微卫星不稳定性的系统和方法
ES2958745T3 (es) * 2018-02-20 2024-02-14 Hoffmann La Roche Detección mejorada de inestabilidad microsatelital
CN113293204B (zh) * 2018-08-21 2024-05-07 元码基因科技(苏州)有限公司 基于二代测序平台检测微卫星不稳定性的引物组合物、试剂盒和方法
CN110305958A (zh) * 2018-11-23 2019-10-08 郑州海普生物医药科技有限公司 一种msi检测方法
KR102506176B1 (ko) * 2020-10-28 2023-03-03 사회복지법인 삼성생명공익재단 현미부수체 불안정성 진단용 마커 조성물 및 프라이머 세트
CN114480632B (zh) * 2020-11-16 2023-05-16 江萤 人微卫星不稳定位点的检测方法及其应用
AU2022341107A1 (en) 2021-09-08 2024-02-29 Amgen Inc. Sotorasib and an egfr antibody for treating cancer comprising a kras g12c mutation
WO2024015360A1 (en) 2022-07-11 2024-01-18 Amgen Inc. Methods of treating cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2129787A1 (en) * 1993-08-27 1995-02-28 Russell G. Higuchi Monitoring multiple amplification reactions simultaneously and analyzing same
WO2001029262A2 (en) * 1999-10-15 2001-04-26 Orchid Biosciences, Inc. Genotyping reagents, kits and methods of use thereof
WO2002010449A2 (en) * 2000-07-28 2002-02-07 Compugen Inc. Oligonucleotide library for detecting rna transcripts and splice variants that populate a transcriptome
EP1340819A1 (de) * 2002-02-28 2003-09-03 Institut National De La Sante Et De La Recherche Medicale (Inserm) Mikrosatellitenmarker

Also Published As

Publication number Publication date
US7662595B2 (en) 2010-02-16
ES2337573T3 (es) 2010-04-27
US20080096197A1 (en) 2008-04-24
WO2006042854A2 (en) 2006-04-27
EP1650311A1 (de) 2006-04-26
EP1650311B1 (de) 2009-12-09
WO2006042854A3 (en) 2006-06-15
ATE451476T1 (de) 2009-12-15

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