ATE451476T1 - Zusammensetzungen und methoden zur bestimmung des mikrosatelliten instabilitäts (msi) status - Google Patents

Zusammensetzungen und methoden zur bestimmung des mikrosatelliten instabilitäts (msi) status

Info

Publication number
ATE451476T1
ATE451476T1 AT04105159T AT04105159T ATE451476T1 AT E451476 T1 ATE451476 T1 AT E451476T1 AT 04105159 T AT04105159 T AT 04105159T AT 04105159 T AT04105159 T AT 04105159T AT E451476 T1 ATE451476 T1 AT E451476T1
Authority
AT
Austria
Prior art keywords
msi
status
microsatellite instability
compositions
methods
Prior art date
Application number
AT04105159T
Other languages
English (en)
Inventor
Peter Findeisen
Sabine Merx
Matthias Kloor
Knebel Doeberitz Magnus Von
Original Assignee
Mtm Lab Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mtm Lab Ag filed Critical Mtm Lab Ag
Application granted granted Critical
Publication of ATE451476T1 publication Critical patent/ATE451476T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT04105159T 2004-10-19 2004-10-19 Zusammensetzungen und methoden zur bestimmung des mikrosatelliten instabilitäts (msi) status ATE451476T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04105159A EP1650311B1 (de) 2004-10-19 2004-10-19 Zusammensetzungen und Methoden zur Bestimmung des Mikrosatelliten Instabilitäts (MSI) Status

Publications (1)

Publication Number Publication Date
ATE451476T1 true ATE451476T1 (de) 2009-12-15

Family

ID=34929729

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04105159T ATE451476T1 (de) 2004-10-19 2004-10-19 Zusammensetzungen und methoden zur bestimmung des mikrosatelliten instabilitäts (msi) status

Country Status (6)

Country Link
US (1) US7662595B2 (de)
EP (1) EP1650311B1 (de)
AT (1) ATE451476T1 (de)
DE (1) DE602004024540D1 (de)
ES (1) ES2337573T3 (de)
WO (1) WO2006042854A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012158385A1 (en) * 2011-05-16 2012-11-22 Baylor Research Institute Detecting dna mismatch repair-deficient colorectal cancers
GB2497510A (en) 2011-11-10 2013-06-19 Harry Cuppens Methods for determining mononucleotide sequence repeats
CN110621784B (zh) * 2017-03-24 2024-06-11 海阳生物材料有限公司 使用双功能pna探针诊断微卫星不稳定性的方法和诊断微卫星不稳定性的试剂盒
US20190156922A1 (en) * 2017-11-16 2019-05-23 Illumina, Inc. Systems and methods for determining microsatellite instability
CN111670254A (zh) * 2018-02-20 2020-09-15 豪夫迈·罗氏有限公司 微卫星不稳定性的改进检测
CN108949757B (zh) * 2018-08-21 2021-07-23 元码基因科技(苏州)有限公司 基于二代测序平台检测微卫星不稳定性的引物组合物、试剂盒和方法
CN110305958A (zh) * 2018-11-23 2019-10-08 郑州海普生物医药科技有限公司 一种msi检测方法
KR102506176B1 (ko) * 2020-10-28 2023-03-03 사회복지법인 삼성생명공익재단 현미부수체 불안정성 진단용 마커 조성물 및 프라이머 세트
CN114480632B (zh) * 2020-11-16 2023-05-16 江萤 人微卫星不稳定位点的检测方法及其应用
WO2023039430A1 (en) 2021-09-08 2023-03-16 Amgen Inc. Sotorasib and an egfr antibody for treating cancer comprising a kras g12c mutation
CN115132327B (zh) * 2022-05-25 2023-03-24 中国医学科学院肿瘤医院 微卫星不稳定预测系统及其构建方法、终端设备及介质
WO2024015360A1 (en) 2022-07-11 2024-01-18 Amgen Inc. Methods of treating cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2129787A1 (en) * 1993-08-27 1995-02-28 Russell G. Higuchi Monitoring multiple amplification reactions simultaneously and analyzing same
AU1085401A (en) * 1999-10-15 2001-04-30 Orchid Biosciences, Inc. Genotyping reagents, kits and methods of use thereof
JP2004508019A (ja) * 2000-07-28 2004-03-18 コンピュジェン　インコーポレイテッド トランスクリプトームの中に場所を占めるｒｎａ転写物及びスプライス変異体を検出するためのオリゴヌクレオチドライブラリー
EP1340819A1 (de) 2002-02-28 2003-09-03 Institut National De La Sante Et De La Recherche Medicale (Inserm) Mikrosatellitenmarker

Also Published As

Publication number Publication date
EP1650311A1 (de) 2006-04-26
DE602004024540D1 (de) 2010-01-21
US20080096197A1 (en) 2008-04-24
WO2006042854A2 (en) 2006-04-27
US7662595B2 (en) 2010-02-16
ES2337573T3 (es) 2010-04-27
WO2006042854A3 (en) 2006-06-15
EP1650311B1 (de) 2009-12-09

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