DE602004018478D1 - Abgeschwächte stämme von vibrio cholerae und diese enthaltende lyophilisierte vakzine - Google Patents

Abgeschwächte stämme von vibrio cholerae und diese enthaltende lyophilisierte vakzine

Info

Publication number
DE602004018478D1
DE602004018478D1 DE602004018478T DE602004018478T DE602004018478D1 DE 602004018478 D1 DE602004018478 D1 DE 602004018478D1 DE 602004018478 T DE602004018478 T DE 602004018478T DE 602004018478 T DE602004018478 T DE 602004018478T DE 602004018478 D1 DE602004018478 D1 DE 602004018478D1
Authority
DE
Germany
Prior art keywords
vibrio cholerae
vaccine containing
lyophilized vaccine
weakened strains
weakened
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004018478T
Other languages
English (en)
Inventor
Gomez Javier Campos
Hernandez Tomas Marcelino Moreira
Gonzalez Boris Luis Rodriguez
Dominguez Karen Marrero
Gutierrez Eriel Martinez
Perez Talena Yamile Ledon
Larranaga Yussuan Silva
Portal Edith Suzarte
Rodriguez Herminia De Delgado
Villavicencio Caridad Urra
Calzada Rafael Alfredo Fando
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CNIC CT NAC INVESTIGACIONES
Centro Nacional de Investigaciones Cientificas
Original Assignee
CNIC CT NAC INVESTIGACIONES
Centro Nacional de Investigaciones Cientificas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CU20030039A external-priority patent/CU23209A1/es
Priority claimed from CU20030084A external-priority patent/CU23206A1/es
Application filed by CNIC CT NAC INVESTIGACIONES, Centro Nacional de Investigaciones Cientificas filed Critical CNIC CT NAC INVESTIGACIONES
Publication of DE602004018478D1 publication Critical patent/DE602004018478D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/107—Vibrio
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE602004018478T 2003-02-20 2004-02-19 Abgeschwächte stämme von vibrio cholerae und diese enthaltende lyophilisierte vakzine Expired - Lifetime DE602004018478D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CU20030039A CU23209A1 (es) 2003-02-20 2003-02-20 Candidatos vacunales vivos con indices mejorados de seguridad ambiental para inmunizar oralmente contra el colera
CU20030084A CU23206A1 (es) 2003-04-17 2003-04-17 Formulaciones para liofilizacion de vacunas vivas atenuadas de vibrio cholerae mejoradas en su seguridad ambiental
PCT/CU2004/000002 WO2004073736A1 (es) 2003-02-20 2004-02-19 Cepas atenuadas de vibrio cholerae y vacunas liofilizadas que las contienen

Publications (1)

Publication Number Publication Date
DE602004018478D1 true DE602004018478D1 (de) 2009-01-29

Family

ID=40203010

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004018478T Expired - Lifetime DE602004018478D1 (de) 2003-02-20 2004-02-19 Abgeschwächte stämme von vibrio cholerae und diese enthaltende lyophilisierte vakzine

Country Status (16)

Country Link
US (1) US7592171B2 (de)
EP (1) EP1614426B1 (de)
JP (1) JP4495143B2 (de)
CN (1) CN100569286C (de)
AP (1) AP1724A (de)
AT (1) ATE417625T1 (de)
BR (1) BRPI0407668A (de)
CA (1) CA2516581C (de)
DE (1) DE602004018478D1 (de)
DK (1) DK1614426T3 (de)
EC (1) ECSP055971A (de)
ES (1) ES2319527T3 (de)
MX (1) MXPA05008774A (de)
OA (1) OA13033A (de)
RU (1) RU2316587C2 (de)
WO (1) WO2004073736A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0325494D0 (en) * 2003-10-31 2003-12-03 Sbl Vaccin Ab Expression system
US20060233837A1 (en) * 2005-04-19 2006-10-19 Gomez Javier C Vibrio cholerae vaccine candidates, the methods of their constructing and medicinal preparations derived thereof
ES2393160T3 (es) * 2007-05-18 2012-12-19 Medimmune, Llc Conservación de materiales bioactivos con espuma liofilizada
CN101880640B (zh) * 2010-02-09 2013-05-29 北京万特尔生物制药有限公司 肺炎克雷伯氏菌(甘露糖敏感血凝)菌毛株
CN101914463B (zh) * 2010-02-09 2012-09-05 北京万特尔生物制药有限公司 普通变形菌(甘露糖敏感血凝)菌毛株
CU24188B1 (es) * 2012-12-27 2016-07-29 Ct De Ingeniería Genética Y Biotecnología Composición vacunal contra el virus dengue
WO2016113322A1 (en) * 2015-01-14 2016-07-21 Centre National De La Recherche Scientifique Genetically modified vibrio cholerae strains and uses thereof
EP3651796A4 (de) * 2017-07-12 2021-06-30 The Brigham and Women's Hospital, Inc. Abgeschwächter cholera-lebendimpfstoff mit probiotischen eigenschaften
CN110184241B (zh) * 2019-05-14 2021-01-26 菲吉乐科(南京)生物科技有限公司 耐高温溶藻弧菌噬菌体及其组合物、试剂盒和应用
CN111004759B (zh) * 2020-01-04 2023-04-07 广东环凯生物科技有限公司 一种霍乱弧菌的稳定剂及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3916304B2 (ja) * 1997-07-25 2007-05-16 三菱レイヨン株式会社 屈折率分布型光ファイバ
GB9808922D0 (en) * 1998-04-24 1998-06-24 Cantab Pharmaceuticals Res Ltd Virus preparations
CU22847A1 (es) * 1998-10-22 2003-04-28 Cnic Ct Nac Investigaciones Conservación de formulaciones vacunales de vibrio cholerae

Also Published As

Publication number Publication date
AP1724A (en) 2007-02-23
WO2004073736A8 (es) 2005-11-17
US20070071775A1 (en) 2007-03-29
RU2005125793A (ru) 2006-05-27
RU2316587C2 (ru) 2008-02-10
DK1614426T3 (da) 2009-04-06
WO2004073736A1 (es) 2004-09-02
ES2319527T3 (es) 2009-05-08
EP1614426A1 (de) 2006-01-11
MXPA05008774A (es) 2006-02-22
AP2005003378A0 (en) 2005-09-30
ECSP055971A (es) 2006-01-16
EP1614426B1 (de) 2008-12-17
CA2516581C (en) 2012-05-15
ATE417625T1 (de) 2009-01-15
OA13033A (en) 2006-11-10
JP4495143B2 (ja) 2010-06-30
CA2516581A1 (en) 2004-09-02
BRPI0407668A (pt) 2006-03-01
JP2006518196A (ja) 2006-08-10
CN1780640A (zh) 2006-05-31
US7592171B2 (en) 2009-09-22
CN100569286C (zh) 2009-12-16

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