DE602004018339D1 - Oxazaborolidine als bakterielle effektoren - Google Patents
Oxazaborolidine als bakterielle effektorenInfo
- Publication number
- DE602004018339D1 DE602004018339D1 DE602004018339T DE602004018339T DE602004018339D1 DE 602004018339 D1 DE602004018339 D1 DE 602004018339D1 DE 602004018339 T DE602004018339 T DE 602004018339T DE 602004018339 T DE602004018339 T DE 602004018339T DE 602004018339 D1 DE602004018339 D1 DE 602004018339D1
- Authority
- DE
- Germany
- Prior art keywords
- bacteria
- composition
- oxazaborolidines
- decreasing
- relates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000012639 bacterial effector Substances 0.000 title 1
- 241000894006 Bacteria Species 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 3
- -1 oxazaborolidine derivative compounds Chemical class 0.000 abstract 3
- 230000001580 bacterial effect Effects 0.000 abstract 2
- 230000003247 decreasing effect Effects 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 231100000433 cytotoxic Toxicity 0.000 abstract 1
- 230000001472 cytotoxic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49900503P | 2003-09-02 | 2003-09-02 | |
PCT/IL2004/000791 WO2005021559A2 (en) | 2003-09-02 | 2004-09-02 | Oxazaborolidines as bacteria effectors |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004018339D1 true DE602004018339D1 (de) | 2009-01-22 |
Family
ID=34272757
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004018339T Active DE602004018339D1 (de) | 2003-09-02 | 2004-09-02 | Oxazaborolidine als bakterielle effektoren |
Country Status (7)
Country | Link |
---|---|
US (1) | US20070155698A1 (de) |
EP (1) | EP1664064B1 (de) |
JP (1) | JP5030590B2 (de) |
AT (1) | ATE417052T1 (de) |
DE (1) | DE602004018339D1 (de) |
ES (1) | ES2319197T3 (de) |
WO (1) | WO2005021559A2 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2008015918A (es) * | 2006-06-12 | 2009-01-14 | Anacor Pharmaceuticals Inc | Compuestos para el tratamiento de enfermedad periodontal. |
EP2136800A4 (de) * | 2007-03-19 | 2011-10-05 | Wisconsin Alumni Res Found | Modulation der bakteriellen quorum-messung mit synthetischen liganden |
EP2529793B1 (de) * | 2007-06-08 | 2016-08-10 | Georgia State University Research Foundation, Inc. | Zusammensetzungen zur Regulierung oder Modulierung von Quorum-Sensing in Bakterien, Verfahren zur Verwendung der Verbindungen sowie Verfahren zur Regulierung oder Modulierung von Quorum-Sensing in Bakterien |
US8624063B2 (en) | 2009-06-30 | 2014-01-07 | Wisconsin Alumni Research Foundation | Non-lactone carbocyclic and heterocyclic antagonists and agonists of bacterial quorum sensing |
EP2459149A2 (de) * | 2009-07-28 | 2012-06-06 | QSlant Limited | Antibakterielle kombinationen mit einem knoblauchextrakt oder einem s-allyl-zystein |
WO2012137164A1 (en) | 2011-04-07 | 2012-10-11 | Biolinerx Ltd. | Antimicrobial compositions, antibiofilm compositions and uses thereof |
WO2012137166A1 (en) | 2011-04-07 | 2012-10-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | An oxoborolidine compound and uses thereof |
FR3029936B1 (fr) * | 2014-12-15 | 2020-01-24 | Biomerieux | Procede et dispositif de caracterisation du pouvoir inhibiteur d'une molecule sur un microorganisme |
US10526278B2 (en) | 2017-10-19 | 2020-01-07 | Wisconsin Alumni Research Foundation | Inhibitors of quorum sensing receptor LasR |
GB202111203D0 (en) | 2021-08-03 | 2021-09-15 | Pathway Intermediates Ltd | Novel applications for oxazaborolidines and new methods of manufacture thereof. |
GB202111761D0 (en) | 2021-08-17 | 2021-09-29 | Collins Mike | Methods for preparing oxazoborolidines |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3137723A (en) * | 1961-09-25 | 1964-06-16 | Olin Mathieson | Boron containing heterocyclic compounds and process for producing them |
JP3498332B2 (ja) * | 1993-10-07 | 2004-02-16 | 住友化学工業株式会社 | 不斉還元剤、および該不斉還元剤を用いる光学活性体の製造方法 |
US6458764B1 (en) * | 1995-05-26 | 2002-10-01 | Theratechnologies Inc. | GRF analogs with increased biological potency |
US5538829A (en) * | 1995-09-05 | 1996-07-23 | Xerox Corporation | Toner compositions with zinc and boron charge enhancing additives |
JP2003532698A (ja) * | 2000-05-10 | 2003-11-05 | プリンストン ユニバーシティ | 細菌の増殖および病理発生を調節するための化合物ならびに方法 |
US6737415B2 (en) * | 2001-08-24 | 2004-05-18 | Quorex Pharmaceuticals, Inc. | Anti-bacterial agents based upon oxoanion binding |
JP2003192596A (ja) * | 2001-12-27 | 2003-07-09 | Shionogi & Co Ltd | 有機ホウ素化合物を含有する新規な抗コクシジウム剤 |
-
2004
- 2004-09-02 EP EP04770462A patent/EP1664064B1/de not_active Not-in-force
- 2004-09-02 JP JP2006525261A patent/JP5030590B2/ja not_active Expired - Fee Related
- 2004-09-02 AT AT04770462T patent/ATE417052T1/de not_active IP Right Cessation
- 2004-09-02 ES ES04770462T patent/ES2319197T3/es active Active
- 2004-09-02 DE DE602004018339T patent/DE602004018339D1/de active Active
- 2004-09-02 WO PCT/IL2004/000791 patent/WO2005021559A2/en active Application Filing
- 2004-09-02 US US10/570,207 patent/US20070155698A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2005021559A2 (en) | 2005-03-10 |
US20070155698A1 (en) | 2007-07-05 |
JP5030590B2 (ja) | 2012-09-19 |
EP1664064B1 (de) | 2008-12-10 |
EP1664064A2 (de) | 2006-06-07 |
JP2007504214A (ja) | 2007-03-01 |
WO2005021559A3 (en) | 2005-04-07 |
ATE417052T1 (de) | 2008-12-15 |
ES2319197T3 (es) | 2009-05-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |