DE602004014189D1 - Zusammensetzungen und verfahren zur behandlung von hepatitis-c-virus (hcv) infektion - Google Patents
Zusammensetzungen und verfahren zur behandlung von hepatitis-c-virus (hcv) infektionInfo
- Publication number
- DE602004014189D1 DE602004014189D1 DE602004014189T DE602004014189T DE602004014189D1 DE 602004014189 D1 DE602004014189 D1 DE 602004014189D1 DE 602004014189 T DE602004014189 T DE 602004014189T DE 602004014189 T DE602004014189 T DE 602004014189T DE 602004014189 D1 DE602004014189 D1 DE 602004014189D1
- Authority
- DE
- Germany
- Prior art keywords
- compound
- methods
- compositions
- hcv
- infection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 241000711549 Hepacivirus C Species 0.000 title 2
- 150000001875 compounds Chemical class 0.000 abstract 4
- 230000002503 metabolic effect Effects 0.000 abstract 2
- 230000009466 transformation Effects 0.000 abstract 2
- 102000013392 Carboxylesterase Human genes 0.000 abstract 1
- 108010051152 Carboxylesterase Proteins 0.000 abstract 1
- 102000004308 Carboxylic Ester Hydrolases Human genes 0.000 abstract 1
- 108090000863 Carboxylic Ester Hydrolases Proteins 0.000 abstract 1
- 102000004157 Hydrolases Human genes 0.000 abstract 1
- 108090000604 Hydrolases Proteins 0.000 abstract 1
- 238000013459 approach Methods 0.000 abstract 1
- 230000002779 inactivation Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 210000002429 large intestine Anatomy 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 210000000813 small intestine Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53154303P | 2003-12-19 | 2003-12-19 | |
| PCT/US2004/042717 WO2005063225A1 (en) | 2003-12-19 | 2004-12-18 | Compositions and methods for treating hepatitis c virus (hcv) infection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602004014189D1 true DE602004014189D1 (de) | 2008-07-10 |
Family
ID=34738664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004014189T Expired - Fee Related DE602004014189D1 (de) | 2003-12-19 | 2004-12-18 | Zusammensetzungen und verfahren zur behandlung von hepatitis-c-virus (hcv) infektion |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20050249805A1 (enExample) |
| EP (1) | EP1699446B1 (enExample) |
| JP (1) | JP2007514763A (enExample) |
| AT (1) | ATE396718T1 (enExample) |
| DE (1) | DE602004014189D1 (enExample) |
| ES (1) | ES2308302T3 (enExample) |
| WO (1) | WO2005063225A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7971730B2 (en) | 2005-08-10 | 2011-07-05 | The Regents Of The University Of California | Collection tubes apparatus, systems and methods |
| JP2010528666A (ja) * | 2007-06-08 | 2010-08-26 | エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント | カルボキシエステラーゼ−１多型およびその使用方法 |
| US20090017108A1 (en) * | 2007-07-11 | 2009-01-15 | Alexander Yuzhakov | Liposome compositions for treatment of hepatitis C |
| US8182826B2 (en) * | 2007-09-11 | 2012-05-22 | Whitmire A Jeffrey | Refreshment towel and applied solution |
| US10966431B2 (en) * | 2007-09-11 | 2021-04-06 | Freedom Towel Holdings, LLC. | Refreshment towel and applied solution |
| US9669405B2 (en) | 2012-10-22 | 2017-06-06 | The Regents Of The University Of California | Sterilizable photopolymer serum separator |
| US10154947B2 (en) | 2016-01-06 | 2018-12-18 | The Procter & Gamble Company | Antiperspirant composition |
| US9730867B2 (en) | 2016-01-06 | 2017-08-15 | The Procter & Gamble Company | Methods of forming a slurry with microcapsules formed from phosphate esters |
| US9732303B2 (en) | 2016-01-06 | 2017-08-15 | The Procter & Gamble Company | Microcapsules formed from phosphate esters and compositions containing same |
| CN110220757B (zh) * | 2019-06-05 | 2021-08-24 | 浙江龙传生物医药科技有限公司 | 用于药物代谢检测的血液保存剂 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4971618A (en) * | 1971-04-16 | 1990-11-20 | Ici Americas Inc. | Herbicide compositions |
| EP1348706B1 (en) * | 2000-12-08 | 2009-08-19 | Takeda Pharmaceutical Company Limited | Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparing the same and use thereof |
| PL374536A1 (en) * | 2002-08-23 | 2005-10-31 | Rigel Pharmaceuticals, Inc. | Pyridyl substituted heterocycles useful for treating or preventing hcv infection |
-
2004
- 2004-12-18 US US11/017,531 patent/US20050249805A1/en not_active Abandoned
- 2004-12-18 WO PCT/US2004/042717 patent/WO2005063225A1/en not_active Ceased
- 2004-12-18 JP JP2006545542A patent/JP2007514763A/ja active Pending
- 2004-12-18 AT AT04814853T patent/ATE396718T1/de not_active IP Right Cessation
- 2004-12-18 EP EP04814853A patent/EP1699446B1/en not_active Expired - Lifetime
- 2004-12-18 ES ES04814853T patent/ES2308302T3/es not_active Expired - Lifetime
- 2004-12-18 DE DE602004014189T patent/DE602004014189D1/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2308302T3 (es) | 2008-12-01 |
| US20050249805A1 (en) | 2005-11-10 |
| EP1699446B1 (en) | 2008-05-28 |
| WO2005063225A8 (en) | 2005-08-25 |
| ATE396718T1 (de) | 2008-06-15 |
| JP2007514763A (ja) | 2007-06-07 |
| WO2005063225A1 (en) | 2005-07-14 |
| EP1699446A1 (en) | 2006-09-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |