DE602004013668D1 - MPTP Affinitätsmarker - Google Patents
MPTP AffinitätsmarkerInfo
- Publication number
- DE602004013668D1 DE602004013668D1 DE602004013668T DE602004013668T DE602004013668D1 DE 602004013668 D1 DE602004013668 D1 DE 602004013668D1 DE 602004013668 T DE602004013668 T DE 602004013668T DE 602004013668 T DE602004013668 T DE 602004013668T DE 602004013668 D1 DE602004013668 D1 DE 602004013668D1
- Authority
- DE
- Germany
- Prior art keywords
- mptp
- affinity marker
- affinity
- marker
- mptp affinity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C255/47—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of rings being part of condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
- C07C49/665—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
- C07C49/683—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
- C07C2603/32—Dibenzocycloheptenes; Hydrogenated dibenzocycloheptenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/93—Spiro compounds
- C07C2603/95—Spiro compounds containing "not free" spiro atoms
- C07C2603/98—Spiro compounds containing "not free" spiro atoms containing at least one ring with more than six ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03008040 | 2003-04-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004013668D1 true DE602004013668D1 (de) | 2008-06-26 |
Family
ID=33155125
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004013668T Expired - Fee Related DE602004013668D1 (de) | 2003-04-14 | 2004-04-07 | MPTP Affinitätsmarker |
Country Status (7)
Country | Link |
---|---|
US (2) | US7101917B2 (de) |
EP (1) | EP1468995B1 (de) |
JP (1) | JP4279718B2 (de) |
CN (1) | CN1323060C (de) |
CA (1) | CA2464042C (de) |
DE (1) | DE602004013668D1 (de) |
ES (1) | ES2305604T3 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070161644A1 (en) * | 2005-01-25 | 2007-07-12 | Stockwell Brent R | Erastin analogs and uses thereof |
WO2007113837A2 (en) * | 2006-04-06 | 2007-10-11 | Ben-Gurion University Of The Negev | N-terminal vdac variants and uses thereof |
WO2007149476A2 (en) * | 2006-06-19 | 2007-12-27 | Trustees Of Columbia University In The City Of New York | Assays for non-apoptotic cell death and uses thereof |
CN106631793B (zh) * | 2016-10-19 | 2019-03-08 | 浙江师范大学 | 一种二苯并环庚烷衍生物的制备方法 |
JP7273584B2 (ja) | 2019-03-29 | 2023-05-15 | ダイハツ工業株式会社 | エンジンシステム |
CN113588768B (zh) * | 2021-05-18 | 2022-07-05 | 国家卫生健康委科学技术研究所 | 一种以分子图像方式定量组织内内源性代谢物的质谱方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4241069A (en) | 1979-09-04 | 1980-12-23 | Miles Laboratories, Inc. | 3-Methylene flavanones and 3-methylene chromanones |
EP0117412A1 (de) | 1983-01-18 | 1984-09-05 | Daicel Chemical Industries, Ltd. | Propenderivate und ihre Verwendung als Pflanzenwachstumshemmer |
EP0118685A1 (de) | 1983-02-07 | 1984-09-19 | Daicel Chemical Industries, Ltd. | Propenderivate und ihre Verwendung als Pflanzenwachstumshemmer |
JPH04225953A (ja) | 1990-05-07 | 1992-08-14 | Shionogi & Co Ltd | スピロ ジベンゾスベラン誘導体 |
US20030044776A1 (en) | 1998-09-25 | 2003-03-06 | James A. Dykens | Compositions and methods for identifying agents that alter mitochondrial permeability transition pores |
JP2003507474A (ja) | 1999-08-20 | 2003-02-25 | フレッド ハッチンソン キャンサー リサーチ センター | bcl−2ファミリーメンバータンパク質を過剰発現する細胞においてアポトーシスを調節するための組成物および方法 |
FR2808197A1 (fr) | 2000-04-28 | 2001-11-02 | Centre Nat Rech Scient | Utilisation du compose ro5-4864 et de composes derives pour la preparation de medicaments destines au traitement des pathologies tumorales |
HU228783B1 (en) | 2001-07-26 | 2013-05-28 | Greenearth Cleaning | Dry cleaning apparatus and method capable of utilizing a siloxane solvent |
-
2004
- 2004-04-05 US US10/817,975 patent/US7101917B2/en not_active Expired - Fee Related
- 2004-04-07 EP EP04008411A patent/EP1468995B1/de not_active Expired - Lifetime
- 2004-04-07 DE DE602004013668T patent/DE602004013668D1/de not_active Expired - Fee Related
- 2004-04-07 ES ES04008411T patent/ES2305604T3/es not_active Expired - Lifetime
- 2004-04-13 CA CA002464042A patent/CA2464042C/en not_active Expired - Fee Related
- 2004-04-14 CN CNB2004100338014A patent/CN1323060C/zh not_active Expired - Fee Related
- 2004-04-14 JP JP2004118943A patent/JP4279718B2/ja not_active Expired - Fee Related
-
2006
- 2006-07-14 US US11/487,119 patent/US7642283B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20040220257A1 (en) | 2004-11-04 |
EP1468995B1 (de) | 2008-05-14 |
CN1609086A (zh) | 2005-04-27 |
CA2464042C (en) | 2009-09-29 |
US7101917B2 (en) | 2006-09-05 |
CA2464042A1 (en) | 2004-10-14 |
ES2305604T3 (es) | 2008-11-01 |
JP2004339204A (ja) | 2004-12-02 |
US7642283B2 (en) | 2010-01-05 |
JP4279718B2 (ja) | 2009-06-17 |
EP1468995A1 (de) | 2004-10-20 |
US20060252822A1 (en) | 2006-11-09 |
CN1323060C (zh) | 2007-06-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |