DE602004005048D1 - 2-methoxymethyl-3-(3,4-dichlorophenyl)-8-azabicyclo ä3.2.1üoctantartrat-salze - Google Patents

2-methoxymethyl-3-(3,4-dichlorophenyl)-8-azabicyclo ä3.2.1üoctantartrat-salze

Info

Publication number
DE602004005048D1
DE602004005048D1 DE602004005048T DE602004005048T DE602004005048D1 DE 602004005048 D1 DE602004005048 D1 DE 602004005048D1 DE 602004005048 T DE602004005048 T DE 602004005048T DE 602004005048 T DE602004005048 T DE 602004005048T DE 602004005048 D1 DE602004005048 D1 DE 602004005048D1
Authority
DE
Germany
Prior art keywords
azabicyclo
dichlorophenyl
methoxymethyl
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004005048T
Other languages
English (en)
Other versions
DE602004005048T2 (de
Inventor
Brian Frostrup
Frank Waetjen
Klaus Snej Jensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NTG Nordic Transport Group AS
Original Assignee
Neurosearch AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch AS filed Critical Neurosearch AS
Publication of DE602004005048D1 publication Critical patent/DE602004005048D1/de
Application granted granted Critical
Publication of DE602004005048T2 publication Critical patent/DE602004005048T2/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE602004005048T 2003-07-31 2004-07-29 2-methoxymethyl-3-(3,4-dichlorophenyl)-8-azabicyclo ä3.2.1üoctantartrat-salze Active DE602004005048T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200301117 2003-07-31
DK200301117 2003-07-31
US49409003P 2003-08-12 2003-08-12
US494090P 2003-08-12
PCT/EP2004/051651 WO2005011694A1 (en) 2003-07-31 2004-07-29 2-methoxymethyl-3-(3,4-dichlorophenyl)-8-azabicyclo[3.2.1]octane tartrate salts

Publications (2)

Publication Number Publication Date
DE602004005048D1 true DE602004005048D1 (de) 2007-04-12
DE602004005048T2 DE602004005048T2 (de) 2007-08-16

Family

ID=36701727

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004005048T Active DE602004005048T2 (de) 2003-07-31 2004-07-29 2-methoxymethyl-3-(3,4-dichlorophenyl)-8-azabicyclo ä3.2.1üoctantartrat-salze

Country Status (22)

Country Link
US (1) US7700619B2 (de)
EP (1) EP1651223B1 (de)
JP (1) JP4711961B2 (de)
CN (1) CN100427484C (de)
AR (1) AR045141A1 (de)
AT (1) ATE355060T1 (de)
AU (1) AU2004260837C1 (de)
BR (1) BRPI0413035A (de)
CA (1) CA2534295A1 (de)
DE (1) DE602004005048T2 (de)
DK (1) DK1651223T3 (de)
ES (1) ES2281827T3 (de)
MY (1) MY140105A (de)
NZ (1) NZ544957A (de)
PL (1) PL1651223T3 (de)
PT (1) PT1651223E (de)
RU (1) RU2348631C2 (de)
SI (1) SI1651223T1 (de)
TW (1) TW200507844A (de)
UA (1) UA86025C2 (de)
WO (1) WO2005011694A1 (de)
ZA (1) ZA200600756B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1940404A2 (de) * 2005-07-12 2008-07-09 Boehringer Ingelheim International GmbH Pharmazeutische zusammensetzung mit 2,3-disubstituierten tropanen zur behandlung von störungen der libido
WO2007028769A1 (en) * 2005-09-05 2007-03-15 Neurosearch A/S Monoamine neurotransmitter re-uptake inhibitor for neuroprotection
EP1779851A1 (de) * 2005-10-31 2007-05-02 Boehringer Ingelheim Pharma GmbH & Co.KG Behandlung von Diabetes
GB0703998D0 (en) * 2007-03-01 2007-04-11 Glaxo Group Ltd Novel salt

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8923209D0 (en) * 1989-10-14 1989-11-29 Wyeth John & Brother Ltd Heterocyclic compounds
ZA971525B (en) * 1996-02-22 1997-10-21 Neurosearch As Tropane derivatives, their preparation and use.
US7381733B2 (en) * 2001-11-30 2008-06-03 Neurosearch A/S Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases

Also Published As

Publication number Publication date
MY140105A (en) 2009-11-30
NZ544957A (en) 2009-02-28
ATE355060T1 (de) 2006-03-15
RU2005141065A (ru) 2006-08-10
ZA200600756B (en) 2007-05-30
AU2004260837A1 (en) 2005-02-10
US7700619B2 (en) 2010-04-20
CN100427484C (zh) 2008-10-22
AU2004260837C1 (en) 2010-08-19
TW200507844A (en) 2005-03-01
UA86025C2 (en) 2009-03-25
RU2348631C2 (ru) 2009-03-10
JP4711961B2 (ja) 2011-06-29
EP1651223A1 (de) 2006-05-03
AR045141A1 (es) 2005-10-19
WO2005011694A1 (en) 2005-02-10
DK1651223T3 (da) 2007-06-11
PL1651223T3 (pl) 2007-07-31
PT1651223E (pt) 2007-03-30
JP2007509030A (ja) 2007-04-12
SI1651223T1 (sl) 2007-08-31
DE602004005048T2 (de) 2007-08-16
EP1651223B1 (de) 2007-02-28
BRPI0413035A (pt) 2006-10-03
US20070043075A1 (en) 2007-02-22
CA2534295A1 (en) 2005-02-10
CN1822837A (zh) 2006-08-23
ES2281827T3 (es) 2007-10-01

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