DE601647C - Process for the production of a radioactive salt mixture effective against animal diseases from the Heidelberg thermal radium brine - Google Patents

Process for the production of a radioactive salt mixture effective against animal diseases from the Heidelberg thermal radium brine

Info

Publication number
DE601647C
DE601647C DEL73205D DEL0073205D DE601647C DE 601647 C DE601647 C DE 601647C DE L73205 D DEL73205 D DE L73205D DE L0073205 D DEL0073205 D DE L0073205D DE 601647 C DE601647 C DE 601647C
Authority
DE
Germany
Prior art keywords
brine
heidelberg
radium
thermal
salt mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DEL73205D
Other languages
German (de)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CLARA LUCHT
KAETHE LUCHT
Original Assignee
CLARA LUCHT
KAETHE LUCHT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CLARA LUCHT, KAETHE LUCHT filed Critical CLARA LUCHT
Priority to DEL73205D priority Critical patent/DE601647C/en
Application granted granted Critical
Publication of DE601647C publication Critical patent/DE601647C/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • A61K51/1289—Devices or containers for impregnation, for emanation, e.g. bottles or jars for radioactive water for use in radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Description

Verfahren zur Herstellung einer gegen Tierseuchen wirksamen radioaktiven Salzmischung aus der Heidelberger Thermal-Radiumsole Es ist ganz bekannt, Sole von Mineralquellen zwecks Gewinnung der in ihr enthaltenen Salze bzw. Salzgemische bis zur Trockne einzudampfen. Systematische Versuche haben nun gezeigt, daß man durch Glas vorliegende Kombinationsverfahren aus der Heidelberger Thermal-Radiumsole ein außerordentlich wirksames Mittel gegen Maul- und Klauenseuche sowie gegen Rotlauf erhalten kann, das bei keiner der zahlreichen bis j,et:tt durchgeführten Erprobungen versagt hat. Das Verfahren besteht darin, daß das Mischungsverhältnis der im Quellwasser vorhandenen Salze im Endprodukt in bestimmter Weise so abgeändert wird, daß in ihm der Gehalt an Alkalichloriden auf einen kleinen Hundertsatz herabgesetzt wird, während der Gehalt an Calciumchlorid und Radium angereichert ist. In dem Produkt sind ferner durch Zusatz von Citronensäure die vorhandenen kohlensauren Salze in citronensaure Salze übergeführt, worauf man die erhaltene Lösung gegebenenfalls auf einen Salzgehalt von 5 bis I o % verdünnt.Process for the production of a radioactive substance which is effective against animal diseases Salt mixture from the Heidelberg thermal radium brine It is well known that brine from Mineral springs for the purpose of extracting the salts or salt mixtures it contains up to evaporate to dryness. Systematic experiments have now shown that you can get through Glas uses a combination process from the Heidelberg thermal radium brine extremely effective remedy against foot-and-mouth disease and against rot can get that in none of the numerous tests carried out up to y, et: tt has failed. The method consists in that the mixing ratio of the in the spring water existing salts in the end product is modified in a certain way so that in it the content of alkali chlorides is reduced to a small percentage, while the content of calcium chloride and radium is enriched. In the product are also by adding citric acid, the existing carbonic acid salts are converted into citric acid Salts transferred, whereupon the resulting solution, if necessary, to a salt content diluted from 5 to 10%.

je I 1 der Sole enthält im wesentlichen 7,5,-, Kaliumchlorid, 52,O g Natriumchlorid, I9, I g Calciumchlorid, 1,9 g Magnesiumchlorid, o,2 g Ammoniunichlorid sowie Hydroca.rbonate des Magnesiums, des Strontiums, Bariums, Eisens und Mangans.Each I 1 of the brine contains essentially 7.5, potassium chloride, 52.0 g sodium chloride, 19.1 g calcium chloride, 1.9 g magnesium chloride, 0.2 g ammonium chloride and hydrocarbonates of magnesium, strontium and barium , Iron and manganese.

Das Verfahren zur Gewinnung der gewünschten Salzmischung aus dieser Sole wird in folgender Weise ausgeführt: Die Sole wird zunächst in bekannter Weise bis zur Trockne eingedampft und dann das Salzgemisch bei etwa 8o° mit Alkohol von etwa 69 bis 95 % ausgewaschen, wobei der größte Teil des Kochsalzes und des Kaliumchlorids ungelöst zurückbleibt. Aus der erhaltenen alkoholischen Lösung wird der Alkohol zwecks Wiedergewinnung abdestillieM worauf die dann zurückbleibenden Salze mit Wasser aufgenommen und zur Überführung der kohlensauren Salze in citronensaure Salze mit Citronensäure versetzt werden. Die Lösung wird gegebenenfalls weiter verdünnt, beispielsweise auf einen Salzgehalt von 5 bis 1o %.The process of obtaining the desired salt mixture from it Brine is carried out in the following way: The brine is initially carried out in a known manner evaporated to dryness and then the salt mixture at about 8o ° with alcohol from about 69 to 95% washed out, with most of the table salt and potassium chloride remains unsolved. The alcoholic solution obtained becomes the alcohol for recovery, distill off and then add the remaining salts with water added and used to convert the carbonic acid salts into citric acid salts Citric acid are added. The solution is optionally further diluted, for example to a salt content of 5 to 1o%.

Claims (1)

PATLNTA NSPRUCII Verfahren zur Herstellung einer gegen Tierseuchen wirksamen radioaktiven Salzmischung aus der Heidelberger Therm.al;-Radiumsole, dadurch- gekennzeichnet, daß die natürliche Sole der Heidelberger Thermalquelle bis zur Trockne eingedampft, der Salzrückstand zwecks Entfernung des. größeren Teiles der Alkalichloride mit Alkohol ausgelaugt, die @erhaltene alkoholische Lösung dann durch Destillation vom Alkohol befreit, der verbleibende Salzrückstand mit Wasser aufgenommen und mit Citronensäure versetzt wird, worauf man diese Lösung gegebenenfälls. weiter verdünnt, beispielsweise auf einen Salzgehalt von 5 bis io %.PATLNTA NSPRUCII Process for the preparation of an animal disease effective radioactive salt mixture from the Heidelberg Therm.al; -radium brine, thereby- characterized that the natural brine of the Heidelberg thermal spring to dryness evaporated, the salt residue for the purpose of removing the greater part of the alkali chlorides leached with alcohol, the @ obtained alcoholic solution then by distillation freed from alcohol, the remaining salt residue taken up with water and with Citric acid is added, whereupon this solution is optionally used. further diluted, for example to a salt content of 5 to 10%.
DEL73205D 1928-08-01 1928-08-01 Process for the production of a radioactive salt mixture effective against animal diseases from the Heidelberg thermal radium brine Expired DE601647C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DEL73205D DE601647C (en) 1928-08-01 1928-08-01 Process for the production of a radioactive salt mixture effective against animal diseases from the Heidelberg thermal radium brine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEL73205D DE601647C (en) 1928-08-01 1928-08-01 Process for the production of a radioactive salt mixture effective against animal diseases from the Heidelberg thermal radium brine

Publications (1)

Publication Number Publication Date
DE601647C true DE601647C (en) 1934-08-21

Family

ID=7283178

Family Applications (1)

Application Number Title Priority Date Filing Date
DEL73205D Expired DE601647C (en) 1928-08-01 1928-08-01 Process for the production of a radioactive salt mixture effective against animal diseases from the Heidelberg thermal radium brine

Country Status (1)

Country Link
DE (1) DE601647C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3563875A1 (en) * 2018-05-04 2019-11-06 Ceské vysoké ucení technické v Praze Radium for radionuclide therapy, in combination with calcium metabolism affecting treatment

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3563875A1 (en) * 2018-05-04 2019-11-06 Ceské vysoké ucení technické v Praze Radium for radionuclide therapy, in combination with calcium metabolism affecting treatment

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