DE60142553D1 - Isolierung und transplantation von retinalen stammzellen - Google Patents
Isolierung und transplantation von retinalen stammzellenInfo
- Publication number
- DE60142553D1 DE60142553D1 DE60142553T DE60142553T DE60142553D1 DE 60142553 D1 DE60142553 D1 DE 60142553D1 DE 60142553 T DE60142553 T DE 60142553T DE 60142553 T DE60142553 T DE 60142553T DE 60142553 D1 DE60142553 D1 DE 60142553D1
- Authority
- DE
- Germany
- Prior art keywords
- transplantation
- stem cells
- insulation
- retinal stem
- vivo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/027—New breeds of vertebrates
- A01K67/0271—Chimeric animals, e.g. comprising exogenous cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/135—Platelet-derived growth factor [PDGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18172300P | 2000-02-11 | 2000-02-11 | |
PCT/US2001/004419 WO2001058460A1 (en) | 2000-02-11 | 2001-02-12 | Isolation and transplantation of retinal stem cells |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60142553D1 true DE60142553D1 (de) | 2010-08-26 |
Family
ID=22665510
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60142553T Expired - Lifetime DE60142553D1 (de) | 2000-02-11 | 2001-02-12 | Isolierung und transplantation von retinalen stammzellen |
Country Status (8)
Country | Link |
---|---|
US (2) | US7514259B2 (de) |
EP (1) | EP1261357B1 (de) |
JP (1) | JP2003521910A (de) |
AT (1) | ATE473751T1 (de) |
AU (2) | AU3499801A (de) |
CA (1) | CA2399434C (de) |
DE (1) | DE60142553D1 (de) |
WO (1) | WO2001058460A1 (de) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020098167A1 (en) | 2000-07-31 | 2002-07-25 | Piero Anversa | Methods and compositions for the repair and/or regeneration of damaged myocardium |
US7862810B2 (en) | 2000-07-31 | 2011-01-04 | New York Medical College | Methods and compositions for the repair and/or regeneration of damaged myocardium |
US7547674B2 (en) * | 2001-06-06 | 2009-06-16 | New York Medical College | Methods and compositions for the repair and/or regeneration of damaged myocardium |
US7312025B2 (en) | 2002-07-12 | 2007-12-25 | University Of Washington | Methods and systems for extended in vitro culture of neuronal cells |
DE602004028768D1 (de) | 2003-06-11 | 2010-09-30 | Japan Science & Tech Agency | Verfahren zur Herstellung von Netzhautneurozyten aus neutralen Stammzellen aus dem Irisgewebe und in dem Verfahren hergestelltes Netzhautneurozyt |
US8790637B2 (en) | 2003-06-27 | 2014-07-29 | DePuy Synthes Products, LLC | Repair and regeneration of ocular tissue using postpartum-derived cells |
US7875272B2 (en) | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
US9572840B2 (en) | 2003-06-27 | 2017-02-21 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
EP1641915B1 (de) | 2003-06-27 | 2016-07-27 | DePuy Synthes Products, Inc. | Reparatur und regenerierung von augengewebe mit postpartum abgeleiteten zellen |
US8491883B2 (en) | 2003-06-27 | 2013-07-23 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of amyotrophic lateral sclerosis using umbilical derived cells |
US8518390B2 (en) | 2003-06-27 | 2013-08-27 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells |
GB0328021D0 (en) | 2003-12-03 | 2004-01-07 | Inst Of Ophthalmology | Method |
JP5340599B2 (ja) | 2004-12-23 | 2013-11-13 | エシコン・インコーポレイテッド | 臍帯組織由来産褥細胞ならびにその製造方法および使用方法 |
WO2006071778A2 (en) | 2004-12-23 | 2006-07-06 | Ethicon Incorporated | Treatment of parkinson's disease and related disorders using postpartum derived cells |
PL1971681T3 (pl) | 2005-12-16 | 2018-01-31 | Depuy Synthes Products Inc | Kompozycje oraz sposoby do hamowania niepożądanej odpowiedzi immunologicznej w przypadku transplantacji z brakiem zgodności tkankowej |
WO2007073552A1 (en) | 2005-12-19 | 2007-06-28 | Ethicon, Inc. | In vitro expansion of postpartum derived cells in roller bottles |
US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
US9061017B2 (en) * | 2006-05-03 | 2015-06-23 | The Schepens Eye Research Institute, Inc. | Isolation and therapeutic application of adult retinal stem cells collected from extra-retinal tissues |
WO2007130060A2 (en) | 2006-05-03 | 2007-11-15 | Schepens Eye Research | Isolation and therapeutic application of adult retinal stem cells collected from extra-retinal tissues |
JP2009544313A (ja) * | 2006-07-24 | 2009-12-17 | インターナショナル ステム セル コーポレイション | 網膜幹細胞由来の合成角膜 |
UA99152C2 (ru) | 2007-10-05 | 2012-07-25 | Этикон, Инкорпорейтед | Восстановление и регенерация почечной ткани с использованием клеток, полученных с человеческой ткани пупочного канатика |
US8236538B2 (en) | 2007-12-20 | 2012-08-07 | Advanced Technologies And Regenerative Medicine, Llc | Methods for sterilizing materials containing biologically active agents |
WO2009132156A1 (en) * | 2008-04-22 | 2009-10-29 | Regenerative Research Foundation | Retinal pigment epithelial stem cells |
US20100098675A1 (en) * | 2008-05-30 | 2010-04-22 | Nikolai Tankovich | Methods for reducing the side effects of ophthalmic laser surgery |
GB0822246D0 (en) * | 2008-12-05 | 2009-01-14 | Reneuron Ltd | Composition |
US10557116B2 (en) | 2008-12-19 | 2020-02-11 | DePuy Synthes Products, Inc. | Treatment of lung and pulmonary diseases and disorders |
US10179900B2 (en) | 2008-12-19 | 2019-01-15 | DePuy Synthes Products, Inc. | Conditioned media and methods of making a conditioned media |
GB0902034D0 (en) | 2009-02-06 | 2009-03-11 | Reneuron Ltd | Method |
WO2010111663A1 (en) | 2009-03-26 | 2010-09-30 | Ethicon, Inc. | Human umbilical cord tissue cells as therapy for alzheimer' s disease |
CN105349492B (zh) * | 2011-05-18 | 2019-04-16 | 加利福尼亚大学董事会 | 用于治疗视网膜疾病的组合物及方法 |
US8563304B2 (en) | 2011-06-14 | 2013-10-22 | The Schepens Eye Research Institute | Low oxygen culture conditions for maintaining retinal progenitor cell multipotency |
CN104837987B (zh) | 2011-12-23 | 2018-10-02 | 德普伊新特斯产品公司 | 人脐带组织来源的细胞的检测 |
US10758572B2 (en) * | 2012-02-17 | 2020-09-01 | The Schepens Eye Research Institute | Phenotype profile of human retinal progenitor cells |
EP2833893B1 (de) | 2012-04-03 | 2018-08-29 | Reneuron Limited | Stammzellenmikropartikel |
GB201302468D0 (en) | 2013-02-12 | 2013-03-27 | Reneuron Ltd | Stem cell product |
RU2494712C1 (ru) * | 2012-05-18 | 2013-10-10 | Федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения и социального развития Российской Федерации | Способ лечения атрофии зрительного нерва различной этиологии |
CA2879322A1 (en) | 2012-07-19 | 2014-01-23 | Reneuron Limited | Stem cell microparticles |
EP2956147B1 (de) | 2013-02-12 | 2022-08-24 | Reneuron Limited | Verfahren zur herstellung von mikropartikeln |
CN103409363B (zh) * | 2013-08-06 | 2015-01-21 | 中国人民解放军总医院 | 感光前体细胞与视网膜组织体外共培养方法 |
GB201317887D0 (en) | 2013-10-09 | 2013-11-20 | Reneuron Ltd | Product |
GB201317889D0 (en) | 2013-10-09 | 2013-11-20 | Reneuron Ltd | Product and use |
US20170248581A1 (en) * | 2014-10-07 | 2017-08-31 | NuTech Medical, Inc. | Mesenchymal Stem Cell Diagnostic Testing |
CH711966A2 (it) * | 2015-12-23 | 2017-06-30 | Pinelli Roberto | Cellule staminali retinali. |
WO2018220490A1 (en) * | 2017-06-02 | 2018-12-06 | Janssen Biotech, Inc. | Method of modulating müller glia cells |
JP7360583B2 (ja) * | 2017-09-14 | 2023-10-13 | 国立研究開発法人理化学研究所 | 網膜組織の製造方法 |
AU2019351134A1 (en) * | 2018-09-27 | 2021-04-15 | The Regents Of The University Of California | Methods of human retinal progenitor cell isolation and culture |
KR102196069B1 (ko) * | 2019-04-17 | 2020-12-29 | 경북대학교 산학협력단 | 망막신경절세포의 분리방법 및 그에 의해 분리된 세포의 용도 |
GB201919021D0 (en) | 2019-12-20 | 2020-02-05 | Reneuron Ltd | Nucleic acid constructs for delivering polynucleotides into exosomes |
GB202114441D0 (en) | 2021-10-08 | 2021-11-24 | Reneuron Ltd | Proteins and extracellular vesicles |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2636968B1 (fr) * | 1988-09-27 | 1992-01-03 | Inst Nat Sante Rech Med | Acide nucleique codant pour l'enzyme de conversion de l'angiotensine (eca) humaine, et ses applications, notamment pour le diagnostic in vitro de l'hypertension arterielle |
EP0732402A3 (de) | 1990-12-14 | 1997-05-21 | Cell Genesys Inc | Chimäre Ketten zur Transduktion von rezeptorverbundenen Signalwegen |
US6071889A (en) | 1991-07-08 | 2000-06-06 | Neurospheres Holdings Ltd. | In vivo genetic modification of growth factor-responsive neural precursor cells |
US5851832A (en) | 1991-07-08 | 1998-12-22 | Neurospheres, Ltd. | In vitro growth and proliferation of multipotent neural stem cells and their progeny |
US5980885A (en) | 1991-07-08 | 1999-11-09 | Neurospheres Holdings Ltd. | Growth factor-induced proliferation of neural precursor cells in vivo |
US5981165A (en) | 1991-07-08 | 1999-11-09 | Neurospheres Holdings Ltd. | In vitro induction of dopaminergic cells |
US5750376A (en) | 1991-07-08 | 1998-05-12 | Neurospheres Holdings Ltd. | In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny |
US5654183A (en) | 1992-07-27 | 1997-08-05 | California Institute Of Technology | Genetically engineered mammalian neural crest stem cells |
EP0658194A1 (de) | 1992-07-27 | 1995-06-21 | California Institute Of Technology | Multipotenten neuronalen säugetierstammzellen |
US5849553A (en) | 1992-07-27 | 1998-12-15 | California Institute Of Technology | Mammalian multipotent neural stem cells |
US5928947A (en) | 1992-07-27 | 1999-07-27 | California Institute Of Technology | Mammalian multipotent neural stem cells |
WO1994009119A1 (en) | 1992-10-16 | 1994-04-28 | Neurospheres Ltd. | Remyelination using neural stem cells |
CA2148138C (en) | 1992-10-28 | 2002-01-08 | Samuel Weiss | Biological factors and neural stem cells |
FR2699191B1 (fr) * | 1992-12-16 | 1995-02-10 | Univ Paris Curie | Nouveaux vecteurs rétroviraux, lignées cellulaires les contenant, et leur utilisation dans le traitement des tumeurs. |
DE69433661T2 (de) | 1993-01-29 | 2005-02-10 | Neurospheres Holding Ltd., Calgary | Genetische modifikation von neuralen stammzellen |
US6033906A (en) | 1993-07-26 | 2000-03-07 | California Institute Of Technology | Methods for differentiating neural stem cells to glial cells using neuregulins |
DK0728194T3 (da) | 1993-11-09 | 2003-04-22 | Neurospheres Holdings Ltd | In situ modifikation og manipulation af stamceller fra centralnervesystemet. |
US6001654A (en) | 1994-01-28 | 1999-12-14 | California Institute Of Technology | Methods for differentiating neural stem cells to neurons or smooth muscle cells using TGT-β super family growth factors |
US5853717A (en) | 1994-07-20 | 1998-12-29 | Cytotherapeutics, Inc. | Methods and compositions of growth control for cells encapsulated within bioartificial organs |
US5935849A (en) | 1994-07-20 | 1999-08-10 | Cytotherapeutics, Inc. | Methods and compositions of growth control for cells encapsulated within bioartificial organs |
JPH10505754A (ja) | 1994-09-23 | 1998-06-09 | ニューロスフィアーズ ホウルディングス リミテッド | Cns機能及び機能障害インビトロモデル |
AU716811B2 (en) | 1994-11-14 | 2000-03-09 | Neurospheres Holdings Ltd | Regulation of neural stem cell proliferation |
US5861283A (en) | 1995-03-31 | 1999-01-19 | The University Of Medicine And Dentistry Of New Jersey | DNA encoding a limbic system-associated membrane protein |
AU2019997A (en) | 1996-03-26 | 1997-10-17 | Neurospheres Holdings Ltd | Manipulation of mitotically active cells of the hippocampal region of the brain |
US5753506A (en) | 1996-05-23 | 1998-05-19 | Cns Stem Cell Technology, Inc. | Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals |
CA2216439A1 (en) | 1996-09-25 | 1998-03-25 | Derek Van Der Kooy | Pharmaceuticals containing retinal stem cells |
US5968829A (en) | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
US6093531A (en) | 1997-09-29 | 2000-07-25 | Neurospheres Holdings Ltd. | Generation of hematopoietic cells from multipotent neural stem cells |
US6165783A (en) | 1997-10-24 | 2000-12-26 | Neuro Spheres Holdings Ltd. | Erythropoietin-mediated neurogenesis |
WO1999055838A1 (en) * | 1998-04-24 | 1999-11-04 | University Of Nebraska Board Of Regents | Compositions and methods for the characterization and transplantation of mammalian retinal stem cells |
US6171610B1 (en) | 1998-04-24 | 2001-01-09 | University Of Massachusetts | Guided development and support of hydrogel-cell compositions |
US5958767A (en) | 1998-08-14 | 1999-09-28 | The Children's Medical Center Corp. | Engraftable human neural stem cells |
US6184035B1 (en) | 1998-11-18 | 2001-02-06 | California Institute Of Technology | Methods for isolation and activation of, and control of differentiation from, skeletal muscle stem or progenitor cells |
WO2000047718A1 (en) | 1999-02-11 | 2000-08-17 | The Salk Institute For Biological Studies | Isolation of stem cells and methods of use thereof |
-
2001
- 2001-02-12 AU AU3499801A patent/AU3499801A/xx active Pending
- 2001-02-12 EP EP01907195A patent/EP1261357B1/de not_active Expired - Lifetime
- 2001-02-12 CA CA2399434A patent/CA2399434C/en not_active Expired - Lifetime
- 2001-02-12 AU AU2001234998A patent/AU2001234998B2/en not_active Expired
- 2001-02-12 JP JP2001557570A patent/JP2003521910A/ja active Pending
- 2001-02-12 WO PCT/US2001/004419 patent/WO2001058460A1/en active Application Filing
- 2001-02-12 DE DE60142553T patent/DE60142553D1/de not_active Expired - Lifetime
- 2001-02-12 AT AT01907195T patent/ATE473751T1/de not_active IP Right Cessation
- 2001-02-12 US US10/203,105 patent/US7514259B2/en not_active Expired - Fee Related
-
2008
- 2008-11-06 US US12/266,116 patent/US20090104694A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2001234998B2 (en) | 2006-06-08 |
JP2003521910A (ja) | 2003-07-22 |
WO2001058460A1 (en) | 2001-08-16 |
AU3499801A (en) | 2001-08-20 |
US20030207450A1 (en) | 2003-11-06 |
EP1261357A1 (de) | 2002-12-04 |
US20090104694A1 (en) | 2009-04-23 |
ATE473751T1 (de) | 2010-07-15 |
EP1261357B1 (de) | 2010-07-14 |
CA2399434C (en) | 2010-10-19 |
US7514259B2 (en) | 2009-04-07 |
CA2399434A1 (en) | 2001-08-16 |
EP1261357A4 (de) | 2004-05-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60142553D1 (de) | Isolierung und transplantation von retinalen stammzellen | |
DK1226233T3 (da) | Multipotente voksne stamceller og fremgangsmåder til isolering heraf | |
WO2008076556A3 (en) | Generation of inner ear cells | |
ATE382681T1 (de) | Verbesserung der herzfunktion durch transplantation mesenchymaler stammzellen | |
DE60031248D1 (de) | Elektroaktive pore | |
DK1337284T3 (da) | Coatingssammensætninger med omskiftelig klæbrighed til oftalmiske implantater | |
MXPA03004793A (es) | Roedores transgenicos transcromosomales para elaborar anticuerpos humnanos. | |
MY147181A (en) | Prostaglandin derivatives. | |
MXPA02004666A (es) | Gelatinas recombinantes. | |
UY27143A1 (es) | Inhibidores de sulfonamida lactama de fxa y método | |
NO20062709L (no) | Stamceller som er egnet for transplantasjon, fremstilling derav og farmasoytiske preperater omfattende nevnte stamceller | |
ATE434639T1 (de) | Wässrige dispersionen von silikon-polyether- blockcopolymeren | |
PL356846A1 (en) | Use of interleukin-6 antagonists for the treatment of diseases characterised by high levels of aromatase | |
EA200701293A1 (ru) | Терапевтическая композиция фактора роста кератиноцитов | |
DK1492869T3 (da) | Transplantataccept-inducerende celler af monocytisk oprindelse, deres fremstilling og anvendelse | |
PL374312A1 (en) | Endothelial stem cells, populations, methods of isolation and use thereof | |
NO2019032I1 (no) | Treosulfan | |
EA200400399A1 (ru) | Способы лечения легочных заболеваний | |
ATE473730T1 (de) | Verwendung von 3-positions-cyclosporin-derivaten für haarwachstum | |
DK1411971T3 (da) | Anvendelse af lang gentraxin PTX3 til behandling af kvindelig sterilitet | |
GT200400241A (es) | Prevencion y tratamiento de enfermedades cardiacas hipertensivas mediante el uso de los estrogenos selectivos8b-vinil-estra-1,3,5,(10)-trien-3,17b-diol y 17b-fluor-9a-vinil-estra-1,3,6,(10)-trien-3, 16a-diol | |
ATE397019T1 (de) | Herstellung von f(ab')2 fragmenten in saügetierzelle | |
ATE493176T1 (de) | Verwendung von 3-positions-cyclosporin-derivaten für haarwachstum | |
EA200300468A1 (ru) | Подавление зависимости опухолевых клеток от фактора роста | |
NO20062639L (no) | Bicykliske pyraxoloncytokininhibitorer |