DE60128011D1 - Abgabesystem für antineoplastische arzneistoffe auf basis dendritischer polymere - Google Patents

Abgabesystem für antineoplastische arzneistoffe auf basis dendritischer polymere

Info

Publication number
DE60128011D1
DE60128011D1 DE60128011T DE60128011T DE60128011D1 DE 60128011 D1 DE60128011 D1 DE 60128011D1 DE 60128011 T DE60128011 T DE 60128011T DE 60128011 T DE60128011 T DE 60128011T DE 60128011 D1 DE60128011 D1 DE 60128011D1
Authority
DE
Germany
Prior art keywords
dendritic polymer
antineoplastic
functional groups
antineoplastic agent
dispensing system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60128011T
Other languages
English (en)
Other versions
DE60128011T2 (de
Inventor
Navid Malik
Ruth Duncan
Donald A Tomalia
Roseita Esfand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dendritic Nanotechnologies Inc
Original Assignee
Dendritic Nanotechnologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dendritic Nanotechnologies Inc filed Critical Dendritic Nanotechnologies Inc
Publication of DE60128011D1 publication Critical patent/DE60128011D1/de
Application granted granted Critical
Publication of DE60128011T2 publication Critical patent/DE60128011T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/595—Polyamides, e.g. nylon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60128011T 2001-10-29 2001-10-29 Abgabesystem für antineoplastische arzneistoffe auf basis dendritischer polymere Expired - Lifetime DE60128011T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2001/048568 WO2003037383A1 (en) 2001-10-29 2001-10-29 An antineoplastic- dendritic polymer drug delivery system

Publications (2)

Publication Number Publication Date
DE60128011D1 true DE60128011D1 (de) 2007-05-31
DE60128011T2 DE60128011T2 (de) 2007-12-27

Family

ID=21743124

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60128011T Expired - Lifetime DE60128011T2 (de) 2001-10-29 2001-10-29 Abgabesystem für antineoplastische arzneistoffe auf basis dendritischer polymere

Country Status (6)

Country Link
EP (1) EP1439859B1 (de)
JP (1) JP2005507933A (de)
CN (1) CN1558777A (de)
AT (1) ATE359828T1 (de)
DE (1) DE60128011T2 (de)
WO (1) WO2003037383A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1930304B (zh) * 2003-11-21 2016-01-06 Anp技术公司 不对称支化的聚合物缀合物和微阵列检测
DE102004039875A1 (de) 2004-08-17 2006-03-09 Universität Dortmund Nanotransportsystem mit dendritischer Architektur
CN1332716C (zh) * 2005-05-25 2007-08-22 北京市海格里斯科技有限公司 一种高分子抗肿瘤顺铂药物及其制备方法
JP5264492B2 (ja) 2005-10-25 2013-08-14 エボニック デグサ ゲーエムベーハー 超分岐ポリマーを含有する調製物
DE102007026397A1 (de) 2007-06-06 2008-12-11 Fu Berlin Nanokomplexe mit dendritischer Struktur zur Einlagerung und/oder zum Transport von monovalenten Metallionen
FR2922452B1 (fr) * 2007-10-19 2010-01-22 Coatex Sas Formulations de composes organoplatiniques en presence de polymeres associatifs, produits obtenus et leurs utilisations
CN101965201B (zh) * 2008-01-30 2013-10-23 堪萨斯大学 淋巴管内化疗药物载体
DE102008042923A1 (de) 2008-10-17 2010-04-22 Evonik Goldschmidt Gmbh Präparate zur gesteuerten Freisetzung von Wirkstoffen
EP2493291B1 (de) * 2009-10-26 2019-05-22 Dendritic Nanotechnologies, Inc. Peham-dendrimere für landwirtschaftliche nutzung
WO2015170573A1 (ja) * 2014-05-08 2015-11-12 公立大学法人大阪府立大学 リンパ節イメージング剤
GR1009107B (el) * 2016-07-11 2017-09-08 Εκεφε Δημοκριτος Καινοτομα λειτουργικα συστηματα μεταφορας αμινοκινολινων και παραγωγων τους βασισμενα σε δενδριτικα πολυμερη με ικανοτητα στοχευσης μιτοχονδριων
CN111116928B (zh) * 2019-10-28 2021-11-12 西北工业大学 一种以双药物分子为基元的超分子超支化聚合物及制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5938934A (en) * 1998-01-13 1999-08-17 Dow Corning Corporation Dendrimer-based nanoscopic sponges and metal composites
ITFO990015A1 (it) * 1999-07-23 2001-01-23 Verdini Antonio "dendrimeri polipeptidici quali trasportatori unimolecolari di farmaci e sostanze biologicamente attive".
EP1118333A1 (de) * 2000-01-18 2001-07-25 Eurand International S.P.A. Zusammensetzungen mit erhöhter oraler Bioverfügbarkeit

Also Published As

Publication number Publication date
EP1439859B1 (de) 2007-04-18
JP2005507933A (ja) 2005-03-24
WO2003037383A1 (en) 2003-05-08
ATE359828T1 (de) 2007-05-15
EP1439859A1 (de) 2004-07-28
DE60128011T2 (de) 2007-12-27
CN1558777A (zh) 2004-12-29

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