DE60126090D1 - Diagnostische methode zur identifizierung von fötaler dna in einer maternalen probe - Google Patents

Diagnostische methode zur identifizierung von fötaler dna in einer maternalen probe

Info

Publication number
DE60126090D1
DE60126090D1 DE60126090T DE60126090T DE60126090D1 DE 60126090 D1 DE60126090 D1 DE 60126090D1 DE 60126090 T DE60126090 T DE 60126090T DE 60126090 T DE60126090 T DE 60126090T DE 60126090 D1 DE60126090 D1 DE 60126090D1
Authority
DE
Germany
Prior art keywords
dna
foetal
identification
sample
diagnostic method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60126090T
Other languages
English (en)
Inventor
Maj Anita Hulten
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
BTG International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BTG International Ltd filed Critical BTG International Ltd
Application granted granted Critical
Publication of DE60126090D1 publication Critical patent/DE60126090D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Electrotherapy Devices (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE60126090T 2000-07-10 2001-07-09 Diagnostische methode zur identifizierung von fötaler dna in einer maternalen probe Expired - Lifetime DE60126090D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0016742.9A GB0016742D0 (en) 2000-07-10 2000-07-10 Diagnostic method
PCT/GB2001/003092 WO2002004672A2 (en) 2000-07-10 2001-07-09 Diagnostic method for the identification of foetal dna in a maternal sample

Publications (1)

Publication Number Publication Date
DE60126090D1 true DE60126090D1 (de) 2007-03-08

Family

ID=9895241

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60126090T Expired - Lifetime DE60126090D1 (de) 2000-07-10 2001-07-09 Diagnostische methode zur identifizierung von fötaler dna in einer maternalen probe

Country Status (10)

Country Link
EP (1) EP1301630B1 (de)
JP (1) JP2004502466A (de)
CN (1) CN100558908C (de)
AT (1) ATE351923T1 (de)
AU (2) AU6932301A (de)
CA (1) CA2414986A1 (de)
DE (1) DE60126090D1 (de)
GB (1) GB0016742D0 (de)
HK (1) HK1060156A1 (de)
WO (1) WO2002004672A2 (de)

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JP2006523082A (ja) 2002-03-01 2006-10-12 ラブジェン， インコーポレイテッド ゲノム内の変異の迅速分析
US6977162B2 (en) 2002-03-01 2005-12-20 Ravgen, Inc. Rapid analysis of variations in a genome
GB0214842D0 (en) * 2002-06-27 2002-08-07 Simeg Ltd Diagnostic method
AU2003268333A1 (en) * 2003-02-28 2004-09-28 Ravgen, Inc. Methods for detection of genetic disorders
WO2004078999A1 (en) * 2003-03-05 2004-09-16 Genetic Technologies Limited Identification of fetal dna and fetal cell markers in maternal plasma or serum
US20100216153A1 (en) * 2004-02-27 2010-08-26 Helicos Biosciences Corporation Methods for detecting fetal nucleic acids and diagnosing fetal abnormalities
WO2006097049A1 (en) * 2005-03-18 2006-09-21 The Chinese University Of Hong Kong A method for the detection of chromosomal aneuploidies
ATE557105T1 (de) 2005-06-23 2012-05-15 Keygene Nv Strategien für eine hohe durchsatzidentifikation und erkennung von polymorphismen
US11111543B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
US9424392B2 (en) 2005-11-26 2016-08-23 Natera, Inc. System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals
US10083273B2 (en) 2005-07-29 2018-09-25 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
US11111544B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
US10081839B2 (en) 2005-07-29 2018-09-25 Natera, Inc System and method for cleaning noisy genetic data and determining chromosome copy number
DK1929039T4 (en) 2005-09-29 2014-02-17 Keygene Nv High throughput-screening af mutageniserede populationer
US10316364B2 (en) 2005-09-29 2019-06-11 Keygene N.V. Method for identifying the source of an amplicon
JP6121642B2 (ja) * 2005-11-26 2017-04-26 ナテラ， インコーポレイテッド 予測を行うための、遺伝子データを清浄化し、そして、そのデータを使用するためのシステムおよび方法
BRPI0709545A2 (pt) * 2006-03-06 2011-07-19 Univ Columbia amplificação especìfica de seqüência de dna fetal de uma mistura de origem fetal-maternal
EP2366801B1 (de) * 2006-06-14 2016-10-19 Verinata Health, Inc Verfahren zur Diagnose fötaler Missbildungen
US8372584B2 (en) 2006-06-14 2013-02-12 The General Hospital Corporation Rare cell analysis using sample splitting and DNA tags
US20100112590A1 (en) 2007-07-23 2010-05-06 The Chinese University Of Hong Kong Diagnosing Fetal Chromosomal Aneuploidy Using Genomic Sequencing With Enrichment
PL2557520T3 (pl) * 2007-07-23 2021-10-11 The Chinese University Of Hong Kong Określanie zaburzenia równowagi sekwencji kwasu nukleinowego
JP2011510660A (ja) * 2008-01-30 2011-04-07 ノバルティス アーゲー 母体血漿中の無細胞胎児ｄｎａの二段階濃縮法
CN102171565B (zh) 2008-08-04 2015-04-29 纳特拉公司 等位基因调用和倍性调用的方法
EP2473638B1 (de) 2009-09-30 2017-08-09 Natera, Inc. Verfahren zur nichtinvasiven pränatalen ploidiezuordnung
JP5770737B2 (ja) * 2009-11-06 2015-08-26 ザ チャイニーズ ユニバーシティ オブ ホンコン サイズに基づくゲノム分析
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11332785B2 (en) 2010-05-18 2022-05-17 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11339429B2 (en) 2010-05-18 2022-05-24 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US10316362B2 (en) 2010-05-18 2019-06-11 Natera, Inc. Methods for simultaneous amplification of target loci
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
US11326208B2 (en) 2010-05-18 2022-05-10 Natera, Inc. Methods for nested PCR amplification of cell-free DNA
US9677118B2 (en) 2014-04-21 2017-06-13 Natera, Inc. Methods for simultaneous amplification of target loci
US11408031B2 (en) 2010-05-18 2022-08-09 Natera, Inc. Methods for non-invasive prenatal paternity testing
CA2798758C (en) 2010-05-18 2019-05-07 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11332793B2 (en) 2010-05-18 2022-05-17 Natera, Inc. Methods for simultaneous amplification of target loci
JP6328934B2 (ja) 2010-12-22 2018-05-23 ナテラ， インコーポレイテッド 非侵襲性出生前親子鑑定法
AU2011358564B9 (en) 2011-02-09 2017-07-13 Natera, Inc Methods for non-invasive prenatal ploidy calling
US9892230B2 (en) 2012-03-08 2018-02-13 The Chinese University Of Hong Kong Size-based analysis of fetal or tumor DNA fraction in plasma
WO2015048535A1 (en) 2013-09-27 2015-04-02 Natera, Inc. Prenatal diagnostic resting standards
US10577655B2 (en) 2013-09-27 2020-03-03 Natera, Inc. Cell free DNA diagnostic testing standards
US10262755B2 (en) 2014-04-21 2019-04-16 Natera, Inc. Detecting cancer mutations and aneuploidy in chromosomal segments
CN106460070B (zh) 2014-04-21 2021-10-08 纳特拉公司 检测染色体片段中的突变和倍性
US20170211143A1 (en) * 2014-07-25 2017-07-27 University Of Washington Methods of determining tissues and/or cell types giving rise to cell-free dna, and methods of identifying a disease or disorder using same
US11479812B2 (en) 2015-05-11 2022-10-25 Natera, Inc. Methods and compositions for determining ploidy
WO2018067517A1 (en) 2016-10-04 2018-04-12 Natera, Inc. Methods for characterizing copy number variation using proximity-litigation sequencing
US10011870B2 (en) 2016-12-07 2018-07-03 Natera, Inc. Compositions and methods for identifying nucleic acid molecules
US10894976B2 (en) 2017-02-21 2021-01-19 Natera, Inc. Compositions, methods, and kits for isolating nucleic acids
CN111867728A (zh) * 2018-01-08 2020-10-30 摇篮基因组公司 分离核酸的方法和试剂盒
US11525159B2 (en) 2018-07-03 2022-12-13 Natera, Inc. Methods for detection of donor-derived cell-free DNA

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AU647741B2 (en) * 1989-12-01 1994-03-31 Regents Of The University Of California, The Methods and compositions for chromosome-specific staining
WO1994002646A1 (en) * 1992-07-17 1994-02-03 Aprogenex Inc. Enriching and identyfying fetal cells in maternal blood for in situ hybridization
GB9704444D0 (en) * 1997-03-04 1997-04-23 Isis Innovation Non-invasive prenatal diagnosis
GB0009784D0 (en) * 2000-04-20 2000-06-07 Simeg Limited Methods for clinical diagnosis

Also Published As

Publication number Publication date
CN1452665A (zh) 2003-10-29
WO2002004672A2 (en) 2002-01-17
JP2004502466A (ja) 2004-01-29
AU6932301A (en) 2002-01-21
EP1301630A2 (de) 2003-04-16
EP1301630B1 (de) 2007-01-17
GB0016742D0 (en) 2000-08-30
WO2002004672A3 (en) 2002-09-06
CN100558908C (zh) 2009-11-11
HK1060156A1 (en) 2004-07-30
CA2414986A1 (en) 2002-01-17
ATE351923T1 (de) 2007-02-15
AU2001269323B2 (en) 2006-08-03

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