DE60120917D1 - Kombinationspräparat zur krebstherapie - Google Patents
Kombinationspräparat zur krebstherapieInfo
- Publication number
- DE60120917D1 DE60120917D1 DE60120917T DE60120917T DE60120917D1 DE 60120917 D1 DE60120917 D1 DE 60120917D1 DE 60120917 T DE60120917 T DE 60120917T DE 60120917 T DE60120917 T DE 60120917T DE 60120917 D1 DE60120917 D1 DE 60120917D1
- Authority
- DE
- Germany
- Prior art keywords
- cancer therapy
- combination preparation
- irinotecan
- temozolomide
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000011275 oncology therapy Methods 0.000 title 1
- BPEGJWRSRHCHSN-UHFFFAOYSA-N Temozolomide Chemical compound O=C1N(C)N=NC2=C(C(N)=O)N=CN21 BPEGJWRSRHCHSN-UHFFFAOYSA-N 0.000 abstract 3
- UWKQSNNFCGGAFS-XIFFEERXSA-N irinotecan Chemical compound C1=C2C(CC)=C3CN(C(C4=C([C@@](C(=O)OC4)(O)CC)C=4)=O)C=4C3=NC2=CC=C1OC(=O)N(CC1)CCC1N1CCCCC1 UWKQSNNFCGGAFS-XIFFEERXSA-N 0.000 abstract 3
- 229960004768 irinotecan Drugs 0.000 abstract 3
- 229960004964 temozolomide Drugs 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17854100P | 2000-01-26 | 2000-01-26 | |
| US178541P | 2000-01-26 | ||
| PCT/US2001/002372 WO2001054678A2 (en) | 2000-01-26 | 2001-01-24 | Combination therapy for cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60120917D1 true DE60120917D1 (de) | 2006-08-03 |
| DE60120917T2 DE60120917T2 (de) | 2007-01-25 |
Family
ID=22652952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60120917T Expired - Fee Related DE60120917T2 (de) | 2000-01-26 | 2001-01-24 | Kombinationspräparat zur krebstherapie |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20030229112A1 (de) |
| EP (1) | EP1251850B1 (de) |
| JP (1) | JP2003521497A (de) |
| AT (1) | ATE330600T1 (de) |
| AU (1) | AU2001236529A1 (de) |
| CA (1) | CA2397523A1 (de) |
| CY (1) | CY1105564T1 (de) |
| DE (1) | DE60120917T2 (de) |
| DK (1) | DK1251850T3 (de) |
| ES (1) | ES2263591T3 (de) |
| MX (1) | MXPA02007242A (de) |
| PT (1) | PT1251850E (de) |
| WO (1) | WO2001054678A2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002328952A1 (en) * | 2001-07-23 | 2003-02-24 | Epidauros Biotechnologie Ag | Irinotecan for treatment of cancer |
| EP1909822B1 (de) | 2005-06-29 | 2013-09-25 | Yeda Research And Development Co., Ltd. | Rekombinante interferon alpha 2 (ifn alpha 2) mutanten |
| EP2066672B1 (de) * | 2006-09-29 | 2015-06-24 | Cipla Limited | Verbessertes verfahren zur herstellung von temozolomid und analoga |
| US20080319039A1 (en) * | 2007-06-25 | 2008-12-25 | Jacqueline Rose Bersch | Unit dosage forms of temozolomide |
| AR076784A1 (es) * | 2009-05-26 | 2011-07-06 | Nerviano Medical Sciences Srl | Combinacion terapeutica que comprende un inhibidor de plk1 y un agente antineoplasico |
| US20120045433A1 (en) * | 2010-08-17 | 2012-02-23 | Kapil Dhingra | Combination therapy |
| US8709419B2 (en) | 2010-08-17 | 2014-04-29 | Hoffmann-La Roche, Inc. | Combination therapy |
| US9295669B2 (en) | 2010-12-14 | 2016-03-29 | Hoffman La-Roche Inc. | Combination therapy for proliferative disorders |
| CN112263579A (zh) * | 2020-11-10 | 2021-01-26 | 天津键凯科技有限公司 | 一种抗肿瘤药物组合物及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2162092T3 (es) * | 1995-08-28 | 2001-12-16 | Schering Corp | Terapia de combinacion para canceres avanzados que comprende temozolomida y cisplatino. |
| US6251886B1 (en) * | 1998-12-07 | 2001-06-26 | Schering Corporation | Methods of using temozolomide in the treatment of cancers |
| US6346524B1 (en) * | 1999-03-30 | 2002-02-12 | Schering Corporation | Cancer treatment with temozolomide |
-
2001
- 2001-01-24 EP EP01908685A patent/EP1251850B1/de not_active Expired - Lifetime
- 2001-01-24 AT AT01908685T patent/ATE330600T1/de not_active IP Right Cessation
- 2001-01-24 DK DK01908685T patent/DK1251850T3/da active
- 2001-01-24 ES ES01908685T patent/ES2263591T3/es not_active Expired - Lifetime
- 2001-01-24 AU AU2001236529A patent/AU2001236529A1/en not_active Abandoned
- 2001-01-24 US US09/768,445 patent/US20030229112A1/en not_active Abandoned
- 2001-01-24 JP JP2001555656A patent/JP2003521497A/ja not_active Withdrawn
- 2001-01-24 PT PT01908685T patent/PT1251850E/pt unknown
- 2001-01-24 WO PCT/US2001/002372 patent/WO2001054678A2/en active IP Right Grant
- 2001-01-24 MX MXPA02007242A patent/MXPA02007242A/es active IP Right Grant
- 2001-01-24 CA CA002397523A patent/CA2397523A1/en not_active Abandoned
- 2001-01-24 DE DE60120917T patent/DE60120917T2/de not_active Expired - Fee Related
-
2006
- 2006-07-31 CY CY20061101074T patent/CY1105564T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2263591T3 (es) | 2006-12-16 |
| JP2003521497A (ja) | 2003-07-15 |
| DE60120917T2 (de) | 2007-01-25 |
| WO2001054678A2 (en) | 2001-08-02 |
| CY1105564T1 (el) | 2010-07-28 |
| ATE330600T1 (de) | 2006-07-15 |
| EP1251850A2 (de) | 2002-10-30 |
| AU2001236529A1 (en) | 2001-08-07 |
| CA2397523A1 (en) | 2001-08-02 |
| DK1251850T3 (da) | 2006-10-23 |
| EP1251850B1 (de) | 2006-06-21 |
| WO2001054678A3 (en) | 2002-01-17 |
| PT1251850E (pt) | 2006-10-31 |
| MXPA02007242A (es) | 2002-12-09 |
| US20030229112A1 (en) | 2003-12-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |