DE60117211D1 - Nachweis von Liganden unter Verwendung von lichtbrechenden Oberflächen-Verfahren - Google Patents

Nachweis von Liganden unter Verwendung von lichtbrechenden Oberflächen-Verfahren

Info

Publication number
DE60117211D1
DE60117211D1 DE60117211T DE60117211T DE60117211D1 DE 60117211 D1 DE60117211 D1 DE 60117211D1 DE 60117211 T DE60117211 T DE 60117211T DE 60117211 T DE60117211 T DE 60117211T DE 60117211 D1 DE60117211 D1 DE 60117211D1
Authority
DE
Germany
Prior art keywords
ligands
detection
refractive surface
surface methods
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60117211T
Other languages
English (en)
Other versions
DE60117211T2 (de
Inventor
Helen V Hsieh
J Bruce Pitner
Jason E Gestwicki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Application granted granted Critical
Publication of DE60117211D1 publication Critical patent/DE60117211D1/de
Publication of DE60117211T2 publication Critical patent/DE60117211T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/808Optical sensing apparatus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/964Chemistry: molecular biology and microbiology including enzyme-ligand conjugate production, e.g. reducing rate of nonproductive linkage
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/805Optical property
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/24Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE60117211T 2000-11-20 2001-10-29 Nachweis von Liganden unter Verwendung von lichtbrechenden Oberflächen-Verfahren Expired - Lifetime DE60117211T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US716566 2000-11-20
US09/716,566 US6576430B1 (en) 2000-11-20 2000-11-20 Detection of ligands by refractive surface methods

Publications (2)

Publication Number Publication Date
DE60117211D1 true DE60117211D1 (de) 2006-04-20
DE60117211T2 DE60117211T2 (de) 2006-08-17

Family

ID=24878522

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60117211T Expired - Lifetime DE60117211T2 (de) 2000-11-20 2001-10-29 Nachweis von Liganden unter Verwendung von lichtbrechenden Oberflächen-Verfahren

Country Status (6)

Country Link
US (1) US6576430B1 (de)
EP (1) EP1209468B1 (de)
JP (1) JP4040287B2 (de)
CA (1) CA2361248C (de)
DE (1) DE60117211T2 (de)
ES (1) ES2257373T3 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7064103B2 (en) * 2002-01-04 2006-06-20 Becton, Dickinson And Company Binding protein as biosensors
EP1563067A4 (de) * 2002-11-04 2006-06-07 Icogenex Corp Verfahren zur identifizierung von agentien, die die struktur und die prozessierung eines membrangebundenen vorläuferproteins modulieren
US6898337B2 (en) * 2003-03-19 2005-05-24 Luna Innovations, Incorporated Fiber-optic apparatus and method for making simultaneous multiple parameter measurements
US7019847B1 (en) 2003-12-09 2006-03-28 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Ring-interferometric sol-gel bio-sensor
US20050148277A1 (en) * 2004-01-02 2005-07-07 Stephen Lister Interactive command-repeater toy system
DE102004026711B4 (de) 2004-05-28 2009-10-08 Airbus Deutschland Gmbh Flugzustands-Sensor für elektronische Komponenten zum Einsatz in Flugzeugen, Verfahren zur Steuerung elektronischer Komponenten an Bord von Flugzeugen und elektronische Komponente
US8158340B2 (en) * 2005-12-28 2012-04-17 Corning Incorporated Methods for detecting conformational changes in bioentities
WO2007124464A2 (en) 2006-04-20 2007-11-01 Becton, Dickinson And Company Thermostable proteins and methods of making and using thereof
JP2009063335A (ja) * 2007-09-05 2009-03-26 Fujifilm Corp 生理活性物質と被験物質との相互作用の測定方法
WO2009039466A1 (en) 2007-09-20 2009-03-26 Vanderbilt University Free solution measurement of molecular interactions by backscattering interferometry
JP5804951B2 (ja) 2009-01-12 2015-11-04 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company 柔軟な特徴部を備える内在の硬いカテーテル及び/又は柔軟なカテーテルアタッチメントの少なくとも1つを有する輸液セット及び/又はパッチポンプ
US9375529B2 (en) * 2009-09-02 2016-06-28 Becton, Dickinson And Company Extended use medical device
US20100316764A1 (en) * 2009-06-10 2010-12-16 Engrain, LLC Flour supplement compositions and methods for preparing wheat flour
US8939928B2 (en) 2009-07-23 2015-01-27 Becton, Dickinson And Company Medical device having capacitive coupling communication and energy harvesting
US10092691B2 (en) * 2009-09-02 2018-10-09 Becton, Dickinson And Company Flexible and conformal patch pump
US8741591B2 (en) 2009-10-09 2014-06-03 The Research Foundation For The State University Of New York pH-insensitive glucose indicator protein
WO2011156713A1 (en) 2010-06-11 2011-12-15 Vanderbilt University Multiplexed interferometric detection system and method
US9950109B2 (en) 2010-11-30 2018-04-24 Becton, Dickinson And Company Slide-activated angled inserter and cantilevered ballistic insertion for intradermal drug infusion
US8795230B2 (en) 2010-11-30 2014-08-05 Becton, Dickinson And Company Adjustable height needle infusion device
US8814831B2 (en) 2010-11-30 2014-08-26 Becton, Dickinson And Company Ballistic microneedle infusion device
US9562853B2 (en) 2011-02-22 2017-02-07 Vanderbilt University Nonaqueous backscattering interferometric methods
EP2831583B1 (de) 2012-03-28 2019-12-18 Becton, Dickinson and Company Hydrogelhaftung an geformten polymeren
US9273949B2 (en) 2012-05-11 2016-03-01 Vanderbilt University Backscattering interferometric methods
US10004845B2 (en) 2014-04-18 2018-06-26 Becton, Dickinson And Company Split piston metering pump
US9416775B2 (en) 2014-07-02 2016-08-16 Becton, Dickinson And Company Internal cam metering pump
EP3247988A4 (de) 2015-01-23 2018-12-19 Vanderbilt University Robustes interferometer und verfahren zur verwendung davon
EP3408649B1 (de) 2016-01-29 2023-06-14 Vanderbilt University Interferometrie mit antwortfunktion in freier lösung

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112721B1 (de) * 1982-12-21 1988-05-18 Ares-Serono N.V. Testverfahren
GB8618133D0 (en) * 1986-07-24 1986-09-03 Pa Consulting Services Biosensors
EP0341927B1 (de) * 1988-05-10 1993-07-14 AMERSHAM INTERNATIONAL plc Biosensoren
US5478755A (en) * 1988-07-25 1995-12-26 Ares Serono Research & Development Ltd. Long range surface plasma resonance immunoassay
WO1991005261A1 (en) * 1989-10-04 1991-04-18 E.I. Du Pont De Nemours And Company Assay method for biological target complexes on the surface of a biosensor
US5955377A (en) * 1991-02-11 1999-09-21 Biostar, Inc. Methods and kits for the amplification of thin film based assays
GB9212416D0 (en) * 1992-06-11 1992-07-22 Medical Res Council Reversible binding substances
SE9201984D0 (sv) * 1992-06-29 1992-06-29 Pharmacia Biosensor Ab Improvement in optical assays
US5494829A (en) * 1992-07-31 1996-02-27 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US5538850A (en) * 1994-04-15 1996-07-23 Hewlett-Packard Company Apparatus and method for intracavity sensing of microscopic properties of chemicals
US5573957A (en) * 1994-09-28 1996-11-12 Spectral Diagnostics, Inc. Monoclonal antibody to human cardiac myoglobin
EP0901630B1 (de) * 1996-05-23 2003-08-20 Inverness Medical Switzerland GmbH Verbesserungen in oder in bezug auf spezifische bindungsassays
SE9604575D0 (sv) 1996-12-12 1996-12-12 Biacore Ab Method and system for analyte determination
US5955378A (en) * 1997-08-20 1999-09-21 Challener; William A. Near normal incidence optical assaying method and system having wavelength and angle sensitivity
US6432723B1 (en) * 1999-01-22 2002-08-13 Clinical Micro Sensors, Inc. Biosensors utilizing ligand induced conformation changes

Also Published As

Publication number Publication date
DE60117211T2 (de) 2006-08-17
JP4040287B2 (ja) 2008-01-30
EP1209468B1 (de) 2006-02-15
EP1209468A3 (de) 2003-05-14
EP1209468A2 (de) 2002-05-29
ES2257373T3 (es) 2006-08-01
US6576430B1 (en) 2003-06-10
JP2002350336A (ja) 2002-12-04
CA2361248C (en) 2011-06-14
CA2361248A1 (en) 2002-05-20

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