DE60116733D1 - Peptide mit antibakterieller wirkung - Google Patents

Peptide mit antibakterieller wirkung

Info

Publication number
DE60116733D1
DE60116733D1 DE60116733T DE60116733T DE60116733D1 DE 60116733 D1 DE60116733 D1 DE 60116733D1 DE 60116733 T DE60116733 T DE 60116733T DE 60116733 T DE60116733 T DE 60116733T DE 60116733 D1 DE60116733 D1 DE 60116733D1
Authority
DE
Germany
Prior art keywords
inhibiting
peptides
antibacterial effect
endotoxemia
tnf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60116733T
Other languages
English (en)
Other versions
DE60116733T2 (de
Inventor
H Mayo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Minnesota
Original Assignee
University of Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Minnesota filed Critical University of Minnesota
Publication of DE60116733D1 publication Critical patent/DE60116733D1/de
Application granted granted Critical
Publication of DE60116733T2 publication Critical patent/DE60116733T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE60116733T 2000-01-20 2001-01-19 Peptide mit antibakterieller wirkung Expired - Lifetime DE60116733T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US17725500P 2000-01-20 2000-01-20
US177255P 2000-01-20
US21029700P 2000-06-08 2000-06-08
US210297P 2000-06-08
PCT/US2001/001916 WO2001053335A2 (en) 2000-01-20 2001-01-19 Peptides with antibacterial activity

Publications (2)

Publication Number Publication Date
DE60116733D1 true DE60116733D1 (de) 2006-04-06
DE60116733T2 DE60116733T2 (de) 2006-11-02

Family

ID=26873090

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60116733T Expired - Lifetime DE60116733T2 (de) 2000-01-20 2001-01-19 Peptide mit antibakterieller wirkung

Country Status (8)

Country Link
US (1) US7144982B2 (de)
EP (1) EP1252181B1 (de)
AT (1) ATE316097T1 (de)
AU (1) AU2001231016A1 (de)
CA (1) CA2397835A1 (de)
DE (1) DE60116733T2 (de)
ES (1) ES2252187T3 (de)
WO (1) WO2001053335A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2255865C (en) * 1996-05-24 2008-10-14 The Regents Of The University Of Minnesota Synthesis of soluble beta-sheet forming peptides
DE60116733T2 (de) 2000-01-20 2006-11-02 Regents Of The University Of Minnesota, Minneapolis Peptide mit antibakterieller wirkung
US7056514B2 (en) 2002-02-20 2006-06-06 Regents Of The University Of Minnesota Partial peptide mimetics and methods
EP1380290A1 (de) 2002-07-09 2004-01-14 Universitair Medisch Centrum Utrecht Cross-Beta-Strukturweg und seine therapeutische Relevanz
CN1711074B (zh) * 2002-11-15 2010-10-06 尼普洛株式会社 脂质体
ES2287687T3 (es) * 2003-01-09 2007-12-16 Genentech, Inc. Purificacion de polipeptidos.
WO2005009457A1 (en) * 2003-05-15 2005-02-03 Sangstat Medical Corporation Rdp58 compositions and methods for inhibiting vascularization of cell populations
EP1689851A2 (de) * 2003-10-17 2006-08-16 Regents Of The University Of Minnesota Modifizierte polypeptide mit therapeutischer aktivität sowie verwendungsverfahren
SI1725580T1 (sl) * 2004-03-17 2009-06-30 Aplagen Gmbh Izosterična transformacija
CA2583092C (en) 2004-10-04 2014-12-30 Regents Of The University Of Minnesota Antiangiogenic calixarene-based peptide mimetics
EP2386861A3 (de) 2005-07-13 2012-07-18 Crossbeta Biosciences B.V. Cross-Beta-Struktur-bindende Verbindungen
US8114832B2 (en) 2005-07-13 2012-02-14 Crossbeta Biosciences B.V. Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition
US10611799B2 (en) * 2017-03-03 2020-04-07 National Tsing Hua University Anti-endotoxin polypeptide
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4938949A (en) 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
US5595887A (en) 1990-07-16 1997-01-21 Bionebraska, Inc. Purification directed cloning of peptides using carbonic anhydrase as the affinity binding segment
US5348942A (en) 1993-03-12 1994-09-20 Xoma Corporation Therapeutic uses of bactericidal/permeability increasing protein products
US5447913A (en) 1994-03-11 1995-09-05 Xoma Corporation Therapeutic uses of bactericidal/permeability-increasing protein dimer products
US5830860A (en) 1994-03-24 1998-11-03 Regents Of The University Of Minnesota Peptides with bactericidal activity and endotoxin neutralizing activity for gram negative bacteria and methods for their use
US5786324A (en) * 1994-03-24 1998-07-28 Regents Of The University Of Minnesota Synthetic peptides with bactericidal activity and endotoxin neutralizing activity for gram negative bacteria and methods for their use
US5955577A (en) 1996-06-27 1999-09-21 Regents Of The University Of Minnesota Method for synthesizing a water-soluble β-sheet forming peptide
WO1999017616A1 (en) 1997-10-07 1999-04-15 New England Medical Center Hospitals, Inc. Structure-based rational design of compounds to inhibit papillomavirus infection
JP4037525B2 (ja) 1998-03-25 2008-01-23 生化学工業株式会社 新規抗菌性ペプチド
DE60116733T2 (de) 2000-01-20 2006-11-02 Regents Of The University Of Minnesota, Minneapolis Peptide mit antibakterieller wirkung

Also Published As

Publication number Publication date
WO2001053335A3 (en) 2001-12-13
WO2001053335A2 (en) 2001-07-26
ES2252187T3 (es) 2006-05-16
EP1252181B1 (de) 2006-01-18
US7144982B2 (en) 2006-12-05
WO2001053335A9 (en) 2002-10-31
CA2397835A1 (en) 2001-07-26
ATE316097T1 (de) 2006-02-15
US20020146406A1 (en) 2002-10-10
AU2001231016A1 (en) 2001-07-31
EP1252181A2 (de) 2002-10-30
DE60116733T2 (de) 2006-11-02

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