DE60115063D1 - Verfahren zur herstellung von menschlichen thrombopoietin-polypeptiden durch säugetierzellkulturen - Google Patents

Verfahren zur herstellung von menschlichen thrombopoietin-polypeptiden durch säugetierzellkulturen

Info

Publication number
DE60115063D1
DE60115063D1 DE60115063T DE60115063T DE60115063D1 DE 60115063 D1 DE60115063 D1 DE 60115063D1 DE 60115063 T DE60115063 T DE 60115063T DE 60115063 T DE60115063 T DE 60115063T DE 60115063 D1 DE60115063 D1 DE 60115063D1
Authority
DE
Germany
Prior art keywords
mammali
manufacture
cell cultures
human thrombopoietin
polypeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60115063T
Other languages
English (en)
Other versions
DE60115063T2 (de
Inventor
Guzikovsky Alfonso Cayota
Porto Alberto Robello
Albisu Franz Pritsch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE60115063D1 publication Critical patent/DE60115063D1/de
Publication of DE60115063T2 publication Critical patent/DE60115063T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/524—Thrombopoietin, i.e. C-MPL ligand
DE60115063T 2000-08-30 2001-08-23 Verfahren zur herstellung von thrombopoietin-polypeptiden Expired - Lifetime DE60115063T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
UY26317A UY26317A1 (es) 2000-08-30 2000-08-30 Sistema de produccion de trombopoyetina humana por celulas de mamiferos en cultivo
UY2631700 2000-08-30
PCT/IB2001/001518 WO2002018569A2 (en) 2000-08-30 2001-08-23 Methods for preparing human thrombopoietin polypeptides by mammalian cell cultures

Publications (2)

Publication Number Publication Date
DE60115063D1 true DE60115063D1 (de) 2005-12-22
DE60115063T2 DE60115063T2 (de) 2006-08-03

Family

ID=25546891

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60115063T Expired - Lifetime DE60115063T2 (de) 2000-08-30 2001-08-23 Verfahren zur herstellung von thrombopoietin-polypeptiden

Country Status (19)

Country Link
US (1) US7371569B2 (de)
EP (1) EP1315805B1 (de)
JP (1) JP2004507269A (de)
KR (1) KR20030029894A (de)
CN (1) CN1451040A (de)
AR (1) AR035341A1 (de)
AT (1) ATE310081T1 (de)
AU (2) AU2001282376B9 (de)
BR (1) BR0113789A (de)
CA (1) CA2457165A1 (de)
DE (1) DE60115063T2 (de)
DK (1) DK1315805T3 (de)
ES (1) ES2253411T3 (de)
IL (1) IL154690A0 (de)
MX (1) MXPA03002762A (de)
NZ (1) NZ524924A (de)
UY (1) UY26317A1 (de)
WO (1) WO2002018569A2 (de)
ZA (1) ZA200302414B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2310501B1 (de) * 2008-07-23 2013-07-03 Boehringer Ingelheim Pharma GmbH & Co. KG Neue regulationselemente
WO2021083366A1 (en) * 2019-11-01 2021-05-06 Biocytogen Pharmaceuticals (Beijing) Co., Ltd. Genetically modified non-human animals with human or chimeric thpo

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1297434C (en) * 1986-04-14 1992-03-17 Kenji Murakami Method of producing peptides, recombinant plasmid for use in the same and animal cells transformed with the same
GB2285446B (en) * 1994-01-03 1999-07-28 Genentech Inc Thrombopoietin
US5766581A (en) * 1994-03-31 1998-06-16 Amgen Inc. Method for treating mammals with monopegylated proteins that stimulates megakaryocyte growth and differentiation
DE19541450C2 (de) * 1995-11-07 1997-10-02 Gsf Forschungszentrum Umwelt Genkonstrukt und dessen Verwendung
US6015662A (en) * 1996-01-23 2000-01-18 Abbott Laboratories Reagents for use as calibrators and controls

Also Published As

Publication number Publication date
UY26317A1 (es) 2000-10-31
DK1315805T3 (da) 2006-03-27
ES2253411T3 (es) 2006-06-01
EP1315805B1 (de) 2005-11-16
CN1451040A (zh) 2003-10-22
US20040072326A1 (en) 2004-04-15
DE60115063T2 (de) 2006-08-03
US7371569B2 (en) 2008-05-13
CA2457165A1 (en) 2002-03-07
ZA200302414B (en) 2004-07-05
WO2002018569A3 (en) 2003-01-09
AU2001282376B9 (en) 2006-12-07
KR20030029894A (ko) 2003-04-16
WO2002018569A2 (en) 2002-03-07
BR0113789A (pt) 2004-08-17
NZ524924A (en) 2005-09-30
JP2004507269A (ja) 2004-03-11
ATE310081T1 (de) 2005-12-15
AU8237601A (en) 2002-03-13
AR035341A1 (es) 2004-05-12
AU2001282376B2 (en) 2006-11-09
EP1315805A2 (de) 2003-06-04
IL154690A0 (en) 2003-09-17
MXPA03002762A (es) 2005-06-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition