DE60115032D1 - Verwendung von spermatophyte pflanzenextrakte mit immunomoduelierender wirkung - Google Patents
Verwendung von spermatophyte pflanzenextrakte mit immunomoduelierender wirkungInfo
- Publication number
- DE60115032D1 DE60115032D1 DE60115032T DE60115032T DE60115032D1 DE 60115032 D1 DE60115032 D1 DE 60115032D1 DE 60115032 T DE60115032 T DE 60115032T DE 60115032 T DE60115032 T DE 60115032T DE 60115032 D1 DE60115032 D1 DE 60115032D1
- Authority
- DE
- Germany
- Prior art keywords
- res
- spermatophyte
- glucosidated
- viniferine
- immuno
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000002519 immonomodulatory effect Effects 0.000 title abstract 2
- 239000000419 plant extract Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- XAXVWWYPKOGXSY-UHFFFAOYSA-N (+)-cis-Vitisin A Natural products C1=CC(O)=CC=C1C1C(C=2C=C(O)C=C(O)C=2)C2=C(C=CC=3C=C(C(O)=CC=3)C3C=4C=C(O)C=C5OC(C(C=45)C4=CC(O)=CC(O)=C4C3C=3C=CC(O)=CC=3)C=3C=CC(O)=CC=3)C=C(O)C=C2O1 XAXVWWYPKOGXSY-UHFFFAOYSA-N 0.000 abstract 1
- FQWLMRXWKZGLFI-YVYUXZJTSA-N (-)-trans-epsilon-viniferin Chemical compound C1=CC(O)=CC=C1\C=C\C1=CC(O)=CC2=C1[C@@H](C=1C=C(O)C=C(O)C=1)[C@H](C=1C=CC(O)=CC=1)O2 FQWLMRXWKZGLFI-YVYUXZJTSA-N 0.000 abstract 1
- PHIHHTIYURVLDB-UHFFFAOYSA-N H-gnetine Natural products C1=CC(O)=CC=C1C=CC1=C(C(C(O2)C=3C=CC(O)=CC=3)C=3C=C(O)C=C(O)C=3)C2=CC2=C1C(C=1C=C(O)C=C(O)C=1)C(C=1C=CC(O)=CC=1)O2 PHIHHTIYURVLDB-UHFFFAOYSA-N 0.000 abstract 1
- LHUHHURKGTUZHU-UHFFFAOYSA-N ampelopsin A Natural products C12=C(O)C=C(O)C=C2C(C=23)C(C=4C=CC(O)=CC=4)OC3=CC(O)=CC=2C(O)C1C1=CC=C(O)C=C1 LHUHHURKGTUZHU-UHFFFAOYSA-N 0.000 abstract 1
- FQWLMRXWKZGLFI-UHFFFAOYSA-N cis epsilon-viniferine Natural products C1=CC(O)=CC=C1C=CC1=CC(O)=CC2=C1C(C=1C=C(O)C=C(O)C=1)C(C=1C=CC(O)=CC=1)O2 FQWLMRXWKZGLFI-UHFFFAOYSA-N 0.000 abstract 1
- WZKKRZSJTLGPHH-UHFFFAOYSA-N cis-vitisin B Natural products Oc1ccc(cc1)C2Oc3cc(O)cc(C=C/c4ccc5OC(C(c5c4)c6cc(O)cc7OC(C(c8cc(O)cc(O)c8)c67)c9ccc(O)cc9)c%10ccc(O)cc%10)c3C2c%11cc(O)cc(O)c%11 WZKKRZSJTLGPHH-UHFFFAOYSA-N 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- YQQUILZPDYJDQJ-KGDQSQJYSA-N hopeaphenol Chemical compound C1=CC(O)=CC=C1[C@H](O1)[C@@H]2C3=CC(O)=CC(O)=C3[C@@H](C=3C=CC(O)=CC=3)[C@H]([C@@H]3C=4C=C(O)C=C5O[C@H]([C@@H](C=45)C4=CC(O)=CC(O)=C4[C@H]3C=3C=CC(O)=CC=3)C=3C=CC(O)=CC=3)C3=C2C1=CC(O)=C3 YQQUILZPDYJDQJ-KGDQSQJYSA-N 0.000 abstract 1
- YQQUILZPDYJDQJ-PLGGFYDZSA-N hopeaphenol Natural products Oc1ccc(cc1)[C@@H]2Oc3cc(O)cc4[C@H]([C@@H]5[C@@H](c6ccc(O)cc6)c7c(O)cc(O)cc7[C@@H]8[C@H](Oc9cc(O)cc5c89)c%10ccc(O)cc%10)[C@@H](c%11ccc(O)cc%11)c%12c(O)cc(O)cc%12[C@@H]2c34 YQQUILZPDYJDQJ-PLGGFYDZSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- DQRZXILSJKXVQV-UHFFFAOYSA-N nepalensinol G Natural products Oc1ccc(cc1)C2OC3=CC(=O)C(=O)C4=C3C2c5cc(O)cc(O)c5C(C4C6C(c7ccc(O)cc7)c8c(O)cc(O)cc8C9C(Oc%10cc(O)cc6c9%10)c%11ccc(O)cc%11)c%12ccc(O)cc%12 DQRZXILSJKXVQV-UHFFFAOYSA-N 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical group C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 abstract 1
- 150000003436 stilbenoids Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Transplantation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM000294 | 2000-05-30 | ||
| IT2000RM000294A IT1317034B1 (it) | 2000-05-30 | 2000-05-30 | Metodo di estrazione di prodotti ad attivita' farmaceutica da piantespermatofite, prodotti cosi' ottenuti e loro impiego in medicina, in |
| PCT/IB2001/000983 WO2001091764A2 (en) | 2000-05-30 | 2001-05-29 | Extracts from spermatophyte plants with immunomodulating activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60115032D1 true DE60115032D1 (de) | 2005-12-22 |
| DE60115032T2 DE60115032T2 (de) | 2006-07-20 |
Family
ID=11454759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60115032T Expired - Lifetime DE60115032T2 (de) | 2000-05-30 | 2001-05-29 | Verwendung von spermatophyte pflanzenextrakte mit immunomoduelierender wirkung |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20040014682A1 (de) |
| EP (1) | EP1292320B1 (de) |
| AT (1) | ATE309843T1 (de) |
| AU (1) | AU2001260542A1 (de) |
| DE (1) | DE60115032T2 (de) |
| DK (1) | DK1292320T3 (de) |
| ES (1) | ES2253379T3 (de) |
| IT (1) | IT1317034B1 (de) |
| WO (1) | WO2001091764A2 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7811996B2 (en) * | 2001-11-02 | 2010-10-12 | The Regents Of The University Of California | Methods and compositions for prevention and treatment of inflammatory disease, autoimmune disease, and transplant rejection |
| KR20030084271A (ko) * | 2002-04-26 | 2003-11-01 | 김영수 | 알파비니페린을 포함하는 관절염 예방 및 치료용 조성물 |
| FR2842103B1 (fr) * | 2002-07-10 | 2005-12-09 | Nouvelles applications cosmetiques de polyphenoles et de leurs derives | |
| US7977049B2 (en) | 2002-08-09 | 2011-07-12 | President And Fellows Of Harvard College | Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms |
| FR2844715B1 (fr) * | 2002-09-20 | 2007-04-27 | Af Consulting | Composition pour des soins de la peau, et contenant un ou des oligomeres de resveratrol, en particulier de l'epsilone-viniferine, et ou certains de leurs derives |
| US20060025337A1 (en) * | 2003-07-01 | 2006-02-02 | President And Fellows Of Harvard College | Sirtuin related therapeutics and diagnostics for neurodegenerative diseases |
| US20060084135A1 (en) * | 2003-07-01 | 2006-04-20 | Howitz Konrad T | Compositions for manipulating the lifespan and stress response of cells and organisms |
| US20050042314A1 (en) * | 2003-08-22 | 2005-02-24 | National Yang-Ming University | Extracts of Polygonum multiflorum Thunb., and preparation process and uses of the same |
| US8017634B2 (en) * | 2003-12-29 | 2011-09-13 | President And Fellows Of Harvard College | Compositions for treating obesity and insulin resistance disorders |
| JP2007527418A (ja) | 2003-12-29 | 2007-09-27 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 肥満及びインシュリン耐性障害を治療又は防止するための組成物 |
| US20060084085A1 (en) * | 2004-06-16 | 2006-04-20 | Sinclair David A | Methods and compositions for modulating Bax-mediated apoptosis |
| WO2006004722A2 (en) * | 2004-06-30 | 2006-01-12 | Biomol Research Laboratories, Inc. | Compositions and methods for selectively activating human sirtuins |
| KR20060029714A (ko) * | 2004-09-02 | 2006-04-07 | 주식회사 유니젠 | 포도나무 수피 추출물을 함유하는 아세틸콜린에스터라제저해제 |
| WO2006076681A2 (en) * | 2005-01-13 | 2006-07-20 | Sirtris Pharmaceuticals, Inc. | Novel compositions for preventing and treating neurodegenerative and blood coagulation disorders |
| WO2006138418A2 (en) * | 2005-06-14 | 2006-12-28 | President And Fellows Of Harvard College | Improvement of cognitive performance with sirtuin activators |
| US20070149466A1 (en) * | 2005-07-07 | 2007-06-28 | Michael Milburn | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
| US7744937B2 (en) | 2005-08-09 | 2010-06-29 | Kraft Foods Global Brands Llc | Chemoprotectants from crucifer seeds and sprouts |
| US20070065623A1 (en) * | 2005-09-21 | 2007-03-22 | Vladek Kasperchik | Laser-imageable coating based on exothermic decomposition |
| EP1844784B1 (de) * | 2006-03-28 | 2010-04-21 | Epitech Group S.r.l. | Eine Pharmazeutische Zusammensetzung zur Behandlung von Pathologien, die durch die allgemeine Immunantwort verursacht werden |
| US20080103103A1 (en) * | 2006-10-30 | 2008-05-01 | Bahram Memarzadeh | Reagents and methods to treat ocular diseases and infection |
| EP2124984B1 (de) * | 2007-01-30 | 2016-06-29 | União Brasileira De Educacão E Assistência - Sponsor Of Da Pucrs | Verfahren zur gewinnung von trans-resveratrol und dieses enthaltende zusammensetzung |
| WO2009012910A1 (en) * | 2007-07-20 | 2009-01-29 | Universita'degli Studi Di Milano | Biologically-active stilbene derivatives and compositions thereof |
| ITFI20080019A1 (it) | 2008-02-11 | 2009-08-12 | Glures S R L | Formulazioni comprendenti piceide e resveratrolo atte a prevenire e inibire la perossidazione lipidica. |
| US7824714B2 (en) * | 2008-06-13 | 2010-11-02 | Development Center For Biotechnology | Chinese herb extract for treating dementia and preparation method thereof |
| JP6009467B2 (ja) | 2011-02-22 | 2016-10-19 | コーディル・シード・カンパニー・インコーポレイテッドＣａｕｄｉｌｌ Ｓｅｅｄ Ｃｏｍｐａｎｙ， Ｉｎｃ． | 噴霧乾燥ミロシナーゼ、及びイソチオシアネートを製造するための使用 |
| WO2012156917A2 (fr) * | 2011-05-19 | 2012-11-22 | Caudalie | Procede d'obtention d'epsilon-viniferine et/ou de resveratrol et produits correspondants |
| CN102627677A (zh) * | 2012-03-22 | 2012-08-08 | 聊城大学 | 从虎杖中分离纯化单体化合物的方法 |
| EP2890499A4 (de) * | 2012-08-29 | 2016-05-25 | Snow Logic Inc | Modulare doppelvektor-fluidsprühdüsen |
| WO2014138823A1 (en) * | 2013-03-15 | 2014-09-18 | Griffith University | Compounds and uses thereof in the treatment/prevention of gram-negative bacterial infections |
| CN104231020B (zh) * | 2013-06-14 | 2016-05-11 | 天津大学 | 抗氧化活性的化合物及用途 |
| CN110172373B (zh) * | 2019-06-14 | 2022-08-05 | 中国农业科学院农产品加工研究所 | 白藜芦醇在花生油中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1276225B1 (it) * | 1995-10-17 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per |
| US6414037B1 (en) * | 1998-01-09 | 2002-07-02 | Pharmascience | Pharmaceutical formulations of resveratrol and methods of use thereof |
| US6022901A (en) * | 1998-05-13 | 2000-02-08 | Pharmascience Inc. | Administration of resveratrol to prevent or treat restenosis following coronary intervention |
| FR2795965B1 (fr) * | 1999-07-08 | 2002-12-27 | Actichem | Procede de fabrication d'un extrait naturel de la vigne concentre en reseratrol et produits |
-
2000
- 2000-05-30 IT IT2000RM000294A patent/IT1317034B1/it active
-
2001
- 2001-05-29 ES ES01934247T patent/ES2253379T3/es not_active Expired - Lifetime
- 2001-05-29 AU AU2001260542A patent/AU2001260542A1/en not_active Abandoned
- 2001-05-29 DK DK01934247T patent/DK1292320T3/da active
- 2001-05-29 WO PCT/IB2001/000983 patent/WO2001091764A2/en active IP Right Grant
- 2001-05-29 AT AT01934247T patent/ATE309843T1/de active
- 2001-05-29 US US10/297,157 patent/US20040014682A1/en not_active Abandoned
- 2001-05-29 EP EP01934247A patent/EP1292320B1/de not_active Expired - Lifetime
- 2001-05-29 DE DE60115032T patent/DE60115032T2/de not_active Expired - Lifetime
-
2007
- 2007-09-21 US US11/859,672 patent/US20080070851A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001091764A3 (en) | 2002-08-15 |
| DE60115032T2 (de) | 2006-07-20 |
| ATE309843T1 (de) | 2005-12-15 |
| WO2001091764A2 (en) | 2001-12-06 |
| AU2001260542A1 (en) | 2001-12-11 |
| ITRM20000294A1 (it) | 2001-11-30 |
| ES2253379T3 (es) | 2006-06-01 |
| ITRM20000294A0 (it) | 2000-05-30 |
| US20080070851A1 (en) | 2008-03-20 |
| DK1292320T3 (da) | 2006-03-27 |
| EP1292320A2 (de) | 2003-03-19 |
| EP1292320B1 (de) | 2005-11-16 |
| US20040014682A1 (en) | 2004-01-22 |
| IT1317034B1 (it) | 2003-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: UNIVERSITA CA'FOSCARI, VENICE, IT Owner name: CONSIGLIO NAZIONALE DELLE RICERCHE, ROM/ROMA, IT Owner name: ISTITUTO AGRARIO DI S. MICHELLE ALL'ADIGE, S. , IT |
|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: CONSIGLIO NAZIONALE DELLE RICERCHE, ROM/ROMA, IT Owner name: FONDAZIONE EDMUND MACH, SAN MICHELE ALL'ADIGE, IT Owner name: UNIVERSITA CA'FOSCARI, VENICE, IT |