DE60104421D1 - Prochelators von radiometall markierten molekülen - Google Patents

Prochelators von radiometall markierten molekülen

Info

Publication number
DE60104421D1
DE60104421D1 DE60104421T DE60104421T DE60104421D1 DE 60104421 D1 DE60104421 D1 DE 60104421D1 DE 60104421 T DE60104421 T DE 60104421T DE 60104421 T DE60104421 T DE 60104421T DE 60104421 D1 DE60104421 D1 DE 60104421D1
Authority
DE
Germany
Prior art keywords
sub
radiometally
prochelators
formula
radiometal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60104421T
Other languages
English (en)
Other versions
DE60104421T2 (de
Inventor
R Maecke
Klaus Eisenwiener
Pia Powell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University Hospital Basel Ch
Original Assignee
Universitaetsspital Basel USB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8168693&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60104421(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Universitaetsspital Basel USB filed Critical Universitaetsspital Basel USB
Publication of DE60104421D1 publication Critical patent/DE60104421D1/de
Application granted granted Critical
Publication of DE60104421T2 publication Critical patent/DE60104421T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
DE60104421T 2000-05-12 2001-05-11 Prochelators von radiometall markierten molekülen Expired - Lifetime DE60104421T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00110084 2000-05-12
EP00110084 2000-05-12
PCT/EP2001/005483 WO2002024235A2 (en) 2000-05-12 2001-05-11 Prochelators of radiometal labeled molecules

Publications (2)

Publication Number Publication Date
DE60104421D1 true DE60104421D1 (de) 2004-08-26
DE60104421T2 DE60104421T2 (de) 2005-09-22

Family

ID=8168693

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60104421T Expired - Lifetime DE60104421T2 (de) 2000-05-12 2001-05-11 Prochelators von radiometall markierten molekülen

Country Status (8)

Country Link
US (1) US20060233704A1 (de)
EP (1) EP1289571B1 (de)
JP (1) JP2004509152A (de)
AT (1) ATE271396T1 (de)
AU (2) AU7748801A (de)
DE (1) DE60104421T2 (de)
ES (1) ES2221903T3 (de)
WO (1) WO2002024235A2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1603598T1 (sl) * 2003-03-19 2009-02-28 Universitaetsspital Basel Radiooznačeni konjugati na osnovi substance P innjihove uporabe
US20060155120A1 (en) * 2003-05-23 2006-07-13 Amedio John C Optically pure and enriched isomers of chelating ligands and contrast agents
US8986650B2 (en) 2005-10-07 2015-03-24 Guerbet Complex folate-NOTA-Ga68
WO2007042504A2 (fr) * 2005-10-07 2007-04-19 Guerbet Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium
JP5518465B2 (ja) * 2006-03-14 2014-06-11 マリンクロッド エルエルシー テトラアザ大員環誘導体の金属錯体
US8758723B2 (en) 2006-04-19 2014-06-24 The Board Of Regents Of The University Of Texas System Compositions and methods for cellular imaging and therapy
KR101653182B1 (ko) * 2006-04-19 2016-09-01 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 세포 영상화 및 치료를 위한 조성물 및 방법
US10925977B2 (en) 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
JP2012508231A (ja) * 2008-11-11 2012-04-05 ナンヤン テクノロジカル ユニヴァーシティー 血管内造影剤
WO2010108125A2 (en) 2009-03-19 2010-09-23 The Johns Hopkins University Psma-targeting compounds and uses thereof
FR2959502B1 (fr) * 2010-04-30 2012-09-07 Nanoh Nanoparticules ultrafines a matrice polyorganosiloxane fonctionnalisee et incluant des complexes metalliques ; leur procede d'obtention et leurs applications en imagerie medicale et/ou therapie
RU2457215C1 (ru) * 2011-04-07 2012-07-27 Закрытое Акционерное Общество "Фарм-Синтез" Октапептид для получения радиофармацевтических средств, радиофармацевтическое средство на его основе и способ диагностики опухолей, экспрессирующих соматостатиновые рецепторы
KR101855509B1 (ko) * 2015-11-12 2018-05-09 한국원자력연구원 방사성 의약품의 제조를 위한 바이알 키트 및 이를 이용한 방사성 의약품의 제조 방법
KR20200004861A (ko) 2017-05-05 2020-01-14 퓨전 파마슈티칼즈 인크. Igf-1r 모노클로날 항체 및 그의 용도
JP2020518673A (ja) 2017-05-05 2020-06-25 フュージョン・ファーマシューティカルズ・インコーポレイテッド 二官能性キレートの薬物動態増強及びその使用
US10093741B1 (en) 2017-05-05 2018-10-09 Fusion Pharmaceuticals Inc. IGF-1R monoclonal antibodies and uses thereof
AU2022250323A1 (en) * 2021-03-31 2023-11-09 Nihon Medi-Physics Co., Ltd. Radioactive complex of anti-egfr antibody, and radiopharmaceutical
DE102021109246B3 (de) 2021-04-13 2022-06-09 ITM Isotope Technologies Munich SE Radiopharmaka zu unterschiedlichen ARTs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW213864B (de) * 1991-08-01 1993-10-01 Squibb & Sons Inc

Also Published As

Publication number Publication date
EP1289571B1 (de) 2004-07-21
ATE271396T1 (de) 2004-08-15
WO2002024235A2 (en) 2002-03-28
AU2001277488B2 (en) 2006-05-18
JP2004509152A (ja) 2004-03-25
AU7748801A (en) 2002-04-02
WO2002024235A3 (en) 2002-08-29
ES2221903T3 (es) 2005-01-16
DE60104421T2 (de) 2005-09-22
US20060233704A1 (en) 2006-10-19
EP1289571A2 (de) 2003-03-12

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: UNIVERSITY HOSPITAL, BASEL, CH

8364 No opposition during term of opposition