DE60100080D1 - Derivate von Aryl- oder Heteroaryl-Quinolinylphosphonsäuren, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel - Google Patents

Derivate von Aryl- oder Heteroaryl-Quinolinylphosphonsäuren, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel

Info

Publication number
DE60100080D1
DE60100080D1 DE60100080T DE60100080T DE60100080D1 DE 60100080 D1 DE60100080 D1 DE 60100080D1 DE 60100080 T DE60100080 T DE 60100080T DE 60100080 T DE60100080 T DE 60100080T DE 60100080 D1 DE60100080 D1 DE 60100080D1
Authority
DE
Germany
Prior art keywords
quinolinylphosphonic
heteroaryl
aryl
derivatives
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60100080T
Other languages
English (en)
Other versions
DE60100080T2 (de
Inventor
Alex Cordi
Patrice Desos
Pierre Lestage
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Application granted granted Critical
Publication of DE60100080D1 publication Critical patent/DE60100080D1/de
Publication of DE60100080T2 publication Critical patent/DE60100080T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/60—Quinoline or hydrogenated quinoline ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE60100080T 2000-02-18 2001-02-16 Derivate von Aryl- oder Heteroaryl-Quinolinylphosphonsäuren, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel Expired - Fee Related DE60100080T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0002013A FR2805262A1 (fr) 2000-02-18 2000-02-18 Nouveaux derives d'acides aryle ou heteroaryle quinolinyl phosphoniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
DE60100080D1 true DE60100080D1 (de) 2003-02-20
DE60100080T2 DE60100080T2 (de) 2003-11-20

Family

ID=8847124

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60100080T Expired - Fee Related DE60100080T2 (de) 2000-02-18 2001-02-16 Derivate von Aryl- oder Heteroaryl-Quinolinylphosphonsäuren, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel

Country Status (23)

Country Link
US (1) US6420386B1 (de)
EP (1) EP1125940B1 (de)
JP (1) JP2001278890A (de)
KR (1) KR20010082704A (de)
CN (1) CN1317489A (de)
AR (1) AR027431A1 (de)
AT (1) ATE231154T1 (de)
AU (1) AU2303901A (de)
BR (1) BR0100600A (de)
CA (1) CA2337301A1 (de)
DE (1) DE60100080T2 (de)
DK (1) DK1125940T3 (de)
EA (1) EA200100157A3 (de)
ES (1) ES2190426T3 (de)
FR (1) FR2805262A1 (de)
HK (1) HK1039943A1 (de)
HU (1) HUP0100751A3 (de)
MX (1) MXPA01001559A (de)
NO (1) NO20010802L (de)
NZ (1) NZ510003A (de)
PL (1) PL345917A1 (de)
SI (1) SI1125940T1 (de)
ZA (1) ZA200101337B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2805260A1 (fr) * 2000-02-18 2001-08-24 Adir Nouveaux derives d'acides 6-sulfamoyl-3-quinolinyl phosphoniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP2348018A4 (de) 2008-09-25 2012-04-25 Kyorin Seiyaku Kk Heterocyclisches biarylderivat und dieses als wirkstoff enthaltender pde-hemmer
US20110224250A1 (en) * 2008-10-09 2011-09-15 Yasushi Kohno Isoquinoline derivative, and pde inhibitor comprising same as active ingredient

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2683818B1 (fr) * 1991-11-14 1993-12-31 Adir Cie Nouveaux derives de 3-sulfonylamino-2-(1h)-quinoleinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5342946A (en) * 1992-12-02 1994-08-30 Guilford Pharmaceuticals Inc. Phosphonoalkylquinolin-2-ones as novel antagonists of non-NMDA ionotropic excitatory amino acid receptors
FR2709489B1 (fr) * 1993-08-31 1995-10-20 Adir Nouveaux dérivés de 2-(1H)-quinoléinone, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2750988B1 (fr) * 1996-07-11 1998-09-18 Adir Nouveaux derives de 2-(1h)-quinoleinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
HUP0100751A3 (en) 2002-09-30
HUP0100751A2 (hu) 2002-01-28
FR2805262A1 (fr) 2001-08-24
CA2337301A1 (fr) 2001-08-18
ZA200101337B (en) 2001-08-21
EA200100157A3 (ru) 2001-10-22
DE60100080T2 (de) 2003-11-20
EP1125940B1 (de) 2003-01-15
HU0100751D0 (en) 2001-04-28
CN1317489A (zh) 2001-10-17
NZ510003A (en) 2001-09-28
AR027431A1 (es) 2003-03-26
PL345917A1 (en) 2001-08-27
ATE231154T1 (de) 2003-02-15
EA200100157A2 (ru) 2001-08-27
MXPA01001559A (es) 2002-08-06
SI1125940T1 (en) 2003-04-30
NO20010802L (no) 2001-08-20
KR20010082704A (ko) 2001-08-30
HK1039943A1 (zh) 2002-05-17
US6420386B1 (en) 2002-07-16
JP2001278890A (ja) 2001-10-10
NO20010802D0 (no) 2001-02-16
AU2303901A (en) 2001-08-23
ES2190426T3 (es) 2003-08-01
EP1125940A1 (de) 2001-08-22
DK1125940T3 (da) 2003-05-05
BR0100600A (pt) 2001-09-18

Similar Documents

Publication Publication Date Title
LTC1345910I2 (lt) Chinazolidino dariniai, minėtus junginius turintys vaistai, jų panaudojimas ir jų gavimo būdas
ATE252562T1 (de) Pyrazolcarbonsäurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE60100186D1 (de) Orale pharmazeutische formulierungen von benzimidazolderivaten und verfahren zu ihrer herstellung
HUP9801044A3 (en) Sulfonylamino-carboxylic acid derivatives, process for their preparation, their use and pharmaceutical compositions containing them
HUP0203142A3 (en) Benzodiazepine derivatives, process for preparation of the compounds, pharmaceutical compositions containing them and their use
HUP0204226A3 (en) Quinazoline derivatives, pharmaceutical compositions containing them, their use and process for the preparation of the compounds
ATE215951T1 (de) Tetracyclische campothecineanalogue, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel und diese enthaltende pharmazeutische zubereitungen
DE60016863D1 (de) Wässrige Emulsion und Verfahren zu ihrer Herstellung
DE60301570D1 (de) 1,2,3-substituierte indolizinderivate, fgf inhibitoren, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
ATE355062T1 (de) Retard-zubereitungen von chinolon-antibiotika und verfahren zu ihrer herstellung
ATE294175T1 (de) 4-sulfonamid-piperidin-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen
HUP0202233A3 (en) Derivatives and analogues of galanthamin, their use, pharmaceutical compositions containing them and process for the preparation of them
DE60100015T2 (de) Benzolsulfonamidderivate und Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
DE60100080T2 (de) Derivate von Aryl- oder Heteroaryl-Quinolinylphosphonsäuren, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
NO975680D0 (no) Oralt, farmasöytisk preparat av piperidinoalkanol-forbindelser i opplösningsform
DE69623491D1 (de) Neue säurederivate des pyrazols, verfahren zu ihrer herstellung, ihre anwendung als medikamente, ihre neue anwendung und die sie enthaltende pharmazeutische zusammensetzungen
DE60100690D1 (de) Benzothiadiazinderivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
DE60200041D1 (de) Indenoindolon-Derivate, Verfahren zu ihrer Herstellung und die enthaltenden pharmazeutischen Zusammensetzungen
DE60200023D1 (de) Isoindoloindolon-Derivate, Verfahren zu ihrer Herstellung und die enthaltende pharmazeutische Zusammensetzungen
DE60000646T2 (de) Pyrrolo[3,4-b]chinolinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE60019763D1 (de) Verfahren zur herstellung von thiazolderivaten
DE60100166D1 (de) 6-Amino oder 6-Hydrazinosulfonyl-3-quinolylphosphonsäurederivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
DE60222515D1 (de) BenzoÄbÜpyranoÄ3,2-hÜacridin-7-on Derivative, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
HUP0303110A3 (en) 5-amino-1-pentene-3-ol substituted derivatives, process for their preparation and pharmaceutical compositions containing them and their use
EE05038B1 (et) B-grupi streptogramiinide derivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja segu

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee