DE60044090D1 - Vitamin-d-derivate mit substituenten an der 2-alpha-position - Google Patents

Vitamin-d-derivate mit substituenten an der 2-alpha-position

Info

Publication number
DE60044090D1
DE60044090D1 DE60044090T DE60044090T DE60044090D1 DE 60044090 D1 DE60044090 D1 DE 60044090D1 DE 60044090 T DE60044090 T DE 60044090T DE 60044090 T DE60044090 T DE 60044090T DE 60044090 D1 DE60044090 D1 DE 60044090D1
Authority
DE
Germany
Prior art keywords
group
vitamin
saturated aliphatic
derivatives
substitutes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60044090T
Other languages
English (en)
Inventor
Hiroaki Takayama
Toshie Fujishima
Yoshitomo Suhara
Ken-Ichi Nihei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE60044090D1 publication Critical patent/DE60044090D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60044090T 1999-08-27 2000-08-25 Vitamin-d-derivate mit substituenten an der 2-alpha-position Expired - Lifetime DE60044090D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP24165099 1999-08-27
PCT/JP2000/005743 WO2001016099A1 (fr) 1999-08-27 2000-08-25 DÉRIVÉS DE VITAMINE D AYANT DES SUBSTITUANTS À LA POSITION 2$g(a)

Publications (1)

Publication Number Publication Date
DE60044090D1 true DE60044090D1 (de) 2010-05-12

Family

ID=17077481

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60044090T Expired - Lifetime DE60044090D1 (de) 1999-08-27 2000-08-25 Vitamin-d-derivate mit substituenten an der 2-alpha-position

Country Status (7)

Country Link
US (1) US20050113349A1 (de)
EP (1) EP1219599B1 (de)
AT (1) ATE462689T1 (de)
AU (1) AU6730600A (de)
DE (1) DE60044090D1 (de)
DK (1) DK1219599T3 (de)
WO (1) WO2001016099A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4443933B2 (ja) * 2002-02-25 2010-03-31 中外製薬株式会社 蛍光偏光法を用いたビタミンｄ３受容体結合活性測定方法
JP2011241170A (ja) * 2010-05-18 2011-12-01 Mercian Corp ビタミンｄ誘導体およびその製造方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0184112B1 (de) * 1984-11-27 1990-05-09 Chugai Seiyaku Kabushiki Kaisha Vitamin D-Derivate und Verfahren zu deren Herstellung
US5401732A (en) * 1989-02-23 1995-03-28 Leo Pharmaceutical Products Ltd. A/S Kemiske Fabrik Produkionsaktiese Skab Vitamin D analogues
US5378695A (en) * 1989-02-23 1995-01-03 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Vitamin D analogues
JP3213092B2 (ja) * 1991-11-01 2001-09-25 中外製薬株式会社 ２β位に置換基を有するビタミンＤ誘導体
JP3493037B2 (ja) * 1991-12-18 2004-02-03 中外製薬株式会社 ２２−オキサコレカルシフェロール誘導体とその製造方法
JP2898882B2 (ja) * 1993-04-05 1999-06-02 ウイスコンシン アラムナイ リサーチ フオンデーシヨン ２−位に置換基を有する１９−ノル−ビタミンｄ３ 化合物
WO1995027697A1 (fr) * 1994-04-11 1995-10-19 Chugai Seiyaku Kabushiki Kaisha Derive de la 22-thiavitamine d¿3?
WO1996001811A1 (en) * 1994-07-11 1996-01-25 The Johns-Hopkins University 2-substituted 1,25-dihydroxyvitamin d3 derivatives
AU4459296A (en) * 1995-01-23 1996-08-14 Chugai Seiyaku Kabushiki Kaisha 2-substituted vitamin d3 derivatives
US5877168A (en) * 1995-02-10 1999-03-02 Chugai Seiyaku Kabushiki Kaisha Vitamin D derivative with substituent at the 2β-position
EP0771789B1 (de) * 1995-10-30 2000-02-16 F. Hoffmann-La Roche Ag 1-Alpha, 26-dihydroxy-D-homo-vitamin D3
US5716946A (en) * 1996-02-13 1998-02-10 Wisconsin Alumni Research Foundation Multiple sclerosis treatment
US5891865A (en) * 1996-10-04 1999-04-06 Wisconsin Alumni Research Foundation Treatment of arthritic disease induced by infectious agents
AU7817298A (en) * 1997-06-06 1998-12-21 Wisconsin Alumni Research Foundation Use of vitamin d compounds to prevent transplant rejection
US5939406A (en) * 1997-07-21 1999-08-17 Wisconsin Alumni Research Foundation 18-substituted-19-nor-vitamin D compounds
WO2000066548A1 (fr) * 1999-04-28 2000-11-09 Chugai Seiyaku Kabushiki Kaisha Derives 2-alkyles de vitamine d
EP1286962B1 (de) * 2000-05-31 2008-06-25 Wisconsin Alumni Research Foundation 2-ethyl und 2-ethyliden-19-nor-vitamin d-verbindungen

Also Published As

Publication number Publication date
WO2001016099A1 (fr) 2001-03-08
AU6730600A (en) 2001-03-26
US20050113349A1 (en) 2005-05-26
DK1219599T3 (da) 2010-05-25
EP1219599B1 (de) 2010-03-31
EP1219599A1 (de) 2002-07-03
ATE462689T1 (de) 2010-04-15
EP1219599A4 (de) 2002-09-11

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Legal Events

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