DE60044030D1 - Markerkomplexe aus konjugierten polymeren - Google Patents

Markerkomplexe aus konjugierten polymeren

Info

Publication number
DE60044030D1
DE60044030D1 DE60044030T DE60044030T DE60044030D1 DE 60044030 D1 DE60044030 D1 DE 60044030D1 DE 60044030 T DE60044030 T DE 60044030T DE 60044030 T DE60044030 T DE 60044030T DE 60044030 D1 DE60044030 D1 DE 60044030D1
Authority
DE
Germany
Prior art keywords
solid support
segment
linked
soluble polymer
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60044030T
Other languages
English (en)
Inventor
Robert C Leif
Lidia Vallarino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Virginia Commonwealth University
Original Assignee
Virginia Commonwealth University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virginia Commonwealth University filed Critical Virginia Commonwealth University
Application granted granted Critical
Publication of DE60044030D1 publication Critical patent/DE60044030D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F289/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds not provided for in groups C08F251/00 - C08F287/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/08—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated side groups
    • C08F290/14—Polymers provided for in subclass C08G
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F291/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L51/00—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L51/08—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to macromolecular compounds obtained otherwise than by reactions only involving unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
DE60044030T 1999-10-08 2000-10-07 Markerkomplexe aus konjugierten polymeren Expired - Lifetime DE60044030D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15871899P 1999-10-08 1999-10-08
PCT/US2000/027787 WO2001027625A1 (en) 1999-10-08 2000-10-07 Conjugated polymer tag complexes

Publications (1)

Publication Number Publication Date
DE60044030D1 true DE60044030D1 (de) 2010-04-29

Family

ID=22569392

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60044030T Expired - Lifetime DE60044030D1 (de) 1999-10-08 2000-10-07 Markerkomplexe aus konjugierten polymeren

Country Status (6)

Country Link
US (1) US8048659B1 (de)
EP (1) EP1221052B1 (de)
AT (1) ATE461451T1 (de)
CA (1) CA2387380C (de)
DE (1) DE60044030D1 (de)
WO (1) WO2001027625A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004508838A (ja) * 2000-09-11 2004-03-25 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク 組合せ蛍光エネルギー移動タグ及びそれらの使用
ATE356222T1 (de) 2000-10-06 2007-03-15 Univ Columbia Massives parallelverfahren zur dekodierung von dna und rna
US9708358B2 (en) 2000-10-06 2017-07-18 The Trustees Of Columbia University In The City Of New York Massive parallel method for decoding DNA and RNA
US9156986B2 (en) 2003-04-03 2015-10-13 Enzo Life Sciences, Inc. Multisignal labeling reagents and processes and uses therefor
US9696298B2 (en) * 2003-04-03 2017-07-04 Enzo Life Sciences, Inc. Multisignal reagents for labeling analytes
CA2557818A1 (en) 2004-03-03 2005-09-15 The Trustees Of Columbia University In The City Of New York Photocleavable fluorescent nucleotides for dna sequencing on chip constructed by site-specific coupling chemistry
WO2007002204A2 (en) 2005-06-21 2007-01-04 The Trustees Of Columbia University In The City Of New York Pyrosequencing methods and related compostions
WO2008069973A2 (en) 2006-12-01 2008-06-12 The Trustees Of Columbia University In The City Of New York Four-color dna sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators
EP4310194A2 (de) 2007-10-19 2024-01-24 The Trustees of Columbia University in the City of New York Entwurf und synthese von spaltbaren fluoreszierenden nukleotiden als reversible terminatoren zur dna-sequenzierung durch synthese
WO2009054922A1 (en) 2007-10-19 2009-04-30 The Trustees Of Columbia University In The City Of New York Dna sequencing with non-fluorescent nucleotide reversible terminators and cleavable label modified nucleotide terminators
CN101397340B (zh) * 2008-10-09 2012-09-26 河北大学 碱性橙人工抗原合成及抗体制备方法
GB0917097D0 (en) 2009-09-29 2009-11-11 King S College London Micellar compositions for use in biological applications
WO2012162429A2 (en) 2011-05-23 2012-11-29 The Trustees Of Columbia University In The City Of New York Dna sequencing by synthesis using raman and infrared spectroscopy detection
CN103013494A (zh) * 2012-11-21 2013-04-03 中北大学 一种键合型聚合物-稀土三元配合物发光材料及其制备方法
CN103882532B (zh) * 2012-12-20 2015-10-21 成都先导药物开发有限公司 一种先导化合物的合成及筛选方法与试剂盒
US10648026B2 (en) 2013-03-15 2020-05-12 The Trustees Of Columbia University In The City Of New York Raman cluster tagged molecules for biological imaging
DE102013205346A1 (de) * 2013-03-26 2014-10-02 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Lanthanoidkomplexbasierte spektroskopische Hämoglobinbestimmung in einem flüssigen biologischen Medium
ES2750337T3 (es) 2014-01-31 2020-03-25 Siemens Healthcare Diagnostics Inc Soportes paramagnéticos para uso como reactivos de ensayo
US11585806B2 (en) 2014-06-13 2023-02-21 Immudex Aps General detection and isolation of specific cells by binding of labeled molecules
US10676487B2 (en) 2015-09-09 2020-06-09 On Target Laboratories, LLC Synthesis and composition of photodynamic therapeutic agents for the targeted treatment of cancer
EP3845663A1 (de) * 2016-01-21 2021-07-07 Selux Diagnostics Inc. Verfahren für schnelltest auf antimikrobielle suszeptibilität
US9834808B2 (en) 2016-01-21 2017-12-05 SeLux Diagnostics, Inc. Methods for rapid antibiotic susceptibility testing
CA3048213A1 (en) 2016-12-23 2018-06-28 Eric Stern Methods for improved rapid antimicrobial susceptibility testing
CN111172299B (zh) * 2018-11-13 2021-11-05 北京大学 Rna代谢标记探针、包含其的试剂盒及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1246789A (en) * 1984-01-13 1988-12-13 Akira Yada Process for preparing water-soluble polymers
US4876190A (en) 1987-10-21 1989-10-24 Becton Dickinson & Company Peridinin-chlorophyll complex as fluorescent label
CA1340527C (en) 1988-05-31 1999-05-04 Lidia Vallarino Macrocyclic complexes of yttrium, the lanthanides and the actinides having peripheral coupling functionalities
DE3840605A1 (de) * 1988-12-02 1990-06-07 Behringwerke Ag Mittel fuer immunchemische tests enthaltend carboxylgruppenhaltige polymere
US5147777A (en) * 1990-06-18 1992-09-15 Eastman Kodak Company Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use
CA2073511A1 (en) * 1990-11-14 1992-05-29 Matthew R. Callstrom Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins
US5696240A (en) * 1991-03-15 1997-12-09 Vallarino; Lidia M. Macrocyclic complexes of yttrium, the lanthanides and the actinides having peripheral coupling functionalities
US5965362A (en) 1992-03-04 1999-10-12 The Regents Of The University Of California Comparative genomic hybridization (CGH)
US5736410A (en) 1992-09-14 1998-04-07 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
FR2707010B1 (de) * 1993-06-25 1995-09-29 Bio Merieux
WO1995002184A1 (en) * 1993-07-06 1995-01-19 Baxter Diagnostics Inc. Water soluble polymers for use in immunoassays and dna hybridization assays
US5891741A (en) 1997-05-16 1999-04-06 Coulter International Corp. Antibody-aminodextran-phycobiliprotein conjugates

Also Published As

Publication number Publication date
CA2387380C (en) 2011-08-02
EP1221052B1 (de) 2010-03-17
WO2001027625A1 (en) 2001-04-19
EP1221052A1 (de) 2002-07-10
EP1221052A4 (de) 2005-03-16
US8048659B1 (en) 2011-11-01
ATE461451T1 (de) 2010-04-15
CA2387380A1 (en) 2001-04-19

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