DE60043823D1 - Chemokine rezeptor - Google Patents

Chemokine rezeptor

Info

Publication number
DE60043823D1
DE60043823D1 DE60043823T DE60043823T DE60043823D1 DE 60043823 D1 DE60043823 D1 DE 60043823D1 DE 60043823 T DE60043823 T DE 60043823T DE 60043823 T DE60043823 T DE 60043823T DE 60043823 D1 DE60043823 D1 DE 60043823D1
Authority
DE
Germany
Prior art keywords
rezeptor
chemokine
methods
expression
modulate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60043823T
Other languages
English (en)
Inventor
Jennifa Gosling
Daniel J Dairaghi
Michael Hanley
Zhenhua Miao
Thomas J Schall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemocentryx Inc
Original Assignee
Chemocentryx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemocentryx Inc filed Critical Chemocentryx Inc
Application granted granted Critical
Publication of DE60043823D1 publication Critical patent/DE60043823D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
DE60043823T 1999-10-12 2000-10-10 Chemokine rezeptor Expired - Lifetime DE60043823D1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US15901599P 1999-10-12 1999-10-12
US15921099P 1999-10-13 1999-10-13
US17297999P 1999-12-20 1999-12-20
US17338999P 1999-12-28 1999-12-28
US18662600P 2000-03-03 2000-03-03
PCT/US2000/028067 WO2001027146A2 (en) 1999-10-12 2000-10-10 Chemokine receptor

Publications (1)

Publication Number Publication Date
DE60043823D1 true DE60043823D1 (en) 2010-03-25

Family

ID=27538581

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60043823T Expired - Lifetime DE60043823D1 (en) 1999-10-12 2000-10-10 Chemokine rezeptor

Country Status (9)

Country Link
EP (1) EP1224222B1 (de)
JP (1) JP4754143B2 (de)
AT (1) ATE457317T1 (de)
AU (1) AU783776B2 (de)
CA (1) CA2387018C (de)
DE (1) DE60043823D1 (de)
DK (1) DK1224222T3 (de)
ES (1) ES2339326T3 (de)
WO (1) WO2001027146A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39849E1 (en) 1999-10-12 2007-09-18 Chemocentryx, Inc. Methods for identifying modulators of CCX CKR activity
US6835547B1 (en) 1999-10-12 2004-12-28 Chemocentryx, Inc. Methods for identifying modulators of CCX CKR activity
WO2001066598A2 (en) * 2000-03-03 2001-09-13 Icos Corporation Chemoattractant receptor characterization and cell selection materials and methods and chemokine receptor ccr11 materials and methods
AU2003250221A1 (en) * 2002-08-19 2004-03-11 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with human cxc chemokine receptor 6(cxcr6)
US20050176073A1 (en) * 2004-02-06 2005-08-11 Chemocentryx, Inc. Cell proliferation associated with CCX CKR expression
US20050208595A1 (en) * 2004-03-19 2005-09-22 Brown Arthur M High throughput assay systems and methods for identifying agents that alter expression of cellular proteins
CN100342017C (zh) 2004-05-10 2007-10-10 中国医学科学院肿瘤医院肿瘤研究所 基因重组趋化抗原疫苗
CN110251674A (zh) 2012-09-06 2019-09-20 阿德莱德研究创新有限公司 预防和/或治疗转移性癌症的产品和方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US5055556A (en) 1981-10-06 1991-10-08 The Board Of Trustees Of The Leland Stanford Jr. Univ. Fluorescent conjugates for analysis of molecules and cells
US5093245A (en) 1988-01-26 1992-03-03 Applied Biosystems Labeling by simultaneous ligation and restriction
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
JPH02307059A (ja) 1989-05-23 1990-12-20 Seiko Instr Inc 反応容器
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
EP0814159B1 (de) 1990-08-29 2005-07-27 GenPharm International, Inc. Transgene Mäuse fähig zur Produktion heterologer Antikörper
US5714350A (en) 1992-03-09 1998-02-03 Protein Design Labs, Inc. Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
GB2273932A (en) 1992-11-24 1994-07-06 Stiefel Laboratories Stable oligonucleotides
US5514555A (en) 1993-03-12 1996-05-07 Center For Blood Research, Inc. Assays and therapeutic methods based on lymphocyte chemoattractants
US5563762A (en) 1994-11-28 1996-10-08 Northern Telecom Limited Capacitor for an integrated circuit and method of formation thereof, and a method of adding on-chip capacitors to an integrated circuit
EP0899332A3 (de) * 1997-08-15 2000-07-05 Smithkline Beecham Corporation G-Protein gekoppelter Rezeptor HFIAO41
US5932445A (en) * 1997-11-07 1999-08-03 Incyte Pharmaceuticals, Inc. Signal peptide-containing proteins
JP2002241399A (ja) * 1997-12-24 2002-08-28 Asahi Kasei Corp ７回膜貫通型受容体蛋白質ｅｔ２４０
AU3749499A (en) * 1998-04-16 1999-11-01 Millenium Pharmaceuticals, Inc. Novel molecules of the bgckr-related protein family and uses thereof
JP2003534765A (ja) * 1998-11-04 2003-11-25 カイロン コーポレイション 単離されたｖｓｈｋ−１レセプターポリペプチドおよびそれを使用する方法
US6620615B1 (en) * 1999-04-23 2003-09-16 Curagen Corporation G-protein coupled receptor—encoding nucleic acids
US9715915B2 (en) 2014-10-30 2017-07-25 Samsung Electronics Co., Ltd. Magneto-resistive devices including a free layer having different magnetic properties during operations

Also Published As

Publication number Publication date
AU1195901A (en) 2001-04-23
AU783776B2 (en) 2005-12-01
DK1224222T3 (da) 2010-05-17
EP1224222A2 (de) 2002-07-24
CA2387018A1 (en) 2001-04-19
JP4754143B2 (ja) 2011-08-24
WO2001027146A2 (en) 2001-04-19
JP2003512028A (ja) 2003-04-02
ATE457317T1 (de) 2010-02-15
WO2001027146A9 (en) 2002-05-10
ES2339326T3 (es) 2010-05-19
CA2387018C (en) 2008-02-12
WO2001027146A3 (en) 2001-11-22
EP1224222B1 (de) 2010-02-10

Similar Documents

Publication Publication Date Title
DE69841038D1 (de)
WO2003002717A3 (en) Biological activity of ak155
EP0668075A3 (de) Nicht-peptidische Tachykininrezeptorantagonisten.
WO2001042288A3 (en) G-protein coupled receptors
DE69709561D1 (de) Östrogen-Rezeptor
ZA9810685B (en) Thrombin receptor antagonists.
WO1999020747A3 (en) HUMAN CHECKPOINT KINASE, hCDS1, COMPOSITIONS AND METHODS
DE60043823D1 (en) Chemokine rezeptor
WO2001087937A3 (en) G-protein coupled receptors
EP1292678B8 (de) G-protein gekoppelte rezeptoren
AU2023499A (en) Pth receptor and screening assay utilizing the same
WO1999033981A3 (en) Human signal peptide-containing proteins
MX9802730A (es) Agonistas receptores hematopoyeticos multifuncionales.
AUPN646795A0 (en) Neuropeptide Y-Y5 receptor
WO2000021986A3 (en) Matrix-remodeling genes
WO2001072836A3 (en) G-protein coupled receptors
WO1999041387A3 (en) Prostate-associated serine protease
WO2002026825A3 (en) G-protein coupled receptors
WO2000003005A3 (en) Human checkpoint kinase
WO2001066742A3 (en) G-protein coupled receptors
WO2000040722A3 (en) Insulin-synthesis genes
WO2002002757A3 (en) Adenylyl and guanylyl cyclases
WO1999015659A3 (en) Human ubiquitin-conjugating enzymes
WO2000028034A3 (en) Cytokine signal regulators
WO2001094415A3 (en) Nuclear hormone receptor

Legal Events

Date Code Title Description
8364 No opposition during term of opposition