DE60040662D1 - Vektor zur integration von heterologen sequenzen in poxvirusgenomen - Google Patents
Vektor zur integration von heterologen sequenzen in poxvirusgenomenInfo
- Publication number
- DE60040662D1 DE60040662D1 DE60040662T DE60040662T DE60040662D1 DE 60040662 D1 DE60040662 D1 DE 60040662D1 DE 60040662 T DE60040662 T DE 60040662T DE 60040662 T DE60040662 T DE 60040662T DE 60040662 D1 DE60040662 D1 DE 60040662D1
- Authority
- DE
- Germany
- Prior art keywords
- sequences
- vector
- heterologic
- integrating
- poxvirus genomes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA199900753 | 1999-05-28 | ||
PCT/EP2000/004786 WO2000073476A1 (en) | 1999-05-28 | 2000-05-25 | Vector for integration of heterologous sequences into poxviral genomes |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60040662D1 true DE60040662D1 (de) | 2008-12-11 |
Family
ID=8097154
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60040662T Expired - Lifetime DE60040662D1 (de) | 1999-05-28 | 2000-05-25 | Vektor zur integration von heterologen sequenzen in poxvirusgenomen |
Country Status (9)
Country | Link |
---|---|
US (2) | US6682742B1 (de) |
EP (1) | EP1180155B1 (de) |
JP (2) | JP5639736B2 (de) |
AT (1) | ATE412762T1 (de) |
AU (1) | AU5397100A (de) |
CA (1) | CA2372709C (de) |
DE (1) | DE60040662D1 (de) |
DK (1) | DK1180155T3 (de) |
WO (1) | WO2000073476A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPP927599A0 (en) * | 1999-03-17 | 1999-04-15 | Curtin University Of Technology | Tinnitus rehabilitation device and method |
ATE412762T1 (de) * | 1999-05-28 | 2008-11-15 | Helmholtz Zentrum Muenchen | Vektor zur integration von heterologen sequenzen in poxvirusgenomen |
DE10143490C2 (de) * | 2001-09-05 | 2003-12-11 | Gsf Forschungszentrum Umwelt | Rekombinantes MVA mit der Fähigkeit zur Expression von HCV Struktur-Antigenen |
AU2007200016B2 (en) * | 2002-05-16 | 2010-04-22 | Bavarian Nordic A/S | Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of modified vaccinia virus ankara |
PL372091A1 (en) * | 2002-05-16 | 2005-07-11 | Bavarian Nordic A/S | Expression of genes in modified vaccinia virus ankara by using the cowpox ati promoter |
NZ536502A (en) | 2002-05-16 | 2005-10-28 | Bavarian Nordic As | Recombinant poxvirus expressing homologous genes inserted into the poxviral genome for inducing an immune response in a mammal |
US7501127B2 (en) * | 2002-05-16 | 2009-03-10 | Bavarian Nordic A/S | Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of Modified Vaccinia virus Ankara |
JP2006515170A (ja) * | 2002-11-25 | 2006-05-25 | バヴァリアン・ノルディック・アクティーゼルスカブ | 少なくとも2つの牛痘atiプロモーターを含む組換えポックスウイルス |
WO2005048957A2 (en) * | 2003-02-20 | 2005-06-02 | Therion Biologics Corporation | Novel insertion sites in pox vectors |
EP1518932A1 (de) * | 2003-09-29 | 2005-03-30 | GSF-Forschungszentrum für Umwelt und Gesundheit GmbH | Mutierte Form des Modifizierten Vaccinia Virus Ankara (MVA) sowie ihre Verwendung |
WO2008076157A2 (en) * | 2006-09-08 | 2008-06-26 | Duke University | Modified vaccinia ankara virus vaccine |
GB201006405D0 (en) | 2010-04-16 | 2010-06-02 | Isis Innovation | Poxvirus expression system |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5364773A (en) * | 1991-03-07 | 1994-11-15 | Virogenetics Corporation | Genetically engineered vaccine strain |
AU614064B2 (en) * | 1986-09-22 | 1991-08-22 | President of Kyoto University, The | Gene for A-type inclusion body of poxvirus |
JPH0795956B2 (ja) * | 1986-09-22 | 1995-10-18 | 京都大学長 | ポックスウイルス由来発現制御領域 |
US5443964A (en) | 1987-08-10 | 1995-08-22 | Duke University | Poxvirus insertion/expression vector |
CA1341245C (en) * | 1988-01-12 | 2001-06-05 | F. Hoffmann-La Roche Ag | Recombinant vaccinia virus mva |
JP2679711B2 (ja) * | 1988-02-09 | 1997-11-19 | 京都大学長 | ボックスウイルスのa型封入体(ati)遺伝子5′上流領域の改良及び当該遺伝子3′下流領域による外来遺伝子発現ベクターの改良 |
US5997878A (en) * | 1991-03-07 | 1999-12-07 | Connaught Laboratories | Recombinant poxvirus-cytomegalovirus, compositions and uses |
DE4405841C1 (de) * | 1994-02-23 | 1995-01-05 | Mayr Anton Prof Dr Med Vet Dr | Multipotente Paramunitätsinducer auf der Basis von Kombinationen von Pockenviruskomponenten, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
UA68327C2 (en) * | 1995-07-04 | 2004-08-16 | Gsf Forschungszentrum Fur Unwe | A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals |
MY150893A (en) | 1996-09-24 | 2014-03-14 | Bavarian Nordic As | Recombinant mva virus expressing dengue virus antigens, and the use thereof in vaccines |
GB9711957D0 (en) | 1997-06-09 | 1997-08-06 | Isis Innovation | Methods and reagents for vaccination |
ATE412762T1 (de) * | 1999-05-28 | 2008-11-15 | Helmholtz Zentrum Muenchen | Vektor zur integration von heterologen sequenzen in poxvirusgenomen |
-
2000
- 2000-05-25 AT AT00938684T patent/ATE412762T1/de active
- 2000-05-25 WO PCT/EP2000/004786 patent/WO2000073476A1/en active Application Filing
- 2000-05-25 US US09/980,029 patent/US6682742B1/en not_active Expired - Lifetime
- 2000-05-25 EP EP00938684A patent/EP1180155B1/de not_active Expired - Lifetime
- 2000-05-25 DK DK00938684T patent/DK1180155T3/da active
- 2000-05-25 DE DE60040662T patent/DE60040662D1/de not_active Expired - Lifetime
- 2000-05-25 JP JP2001500788A patent/JP5639736B2/ja not_active Expired - Lifetime
- 2000-05-25 AU AU53971/00A patent/AU5397100A/en not_active Abandoned
- 2000-05-25 CA CA2372709A patent/CA2372709C/en not_active Expired - Lifetime
-
2003
- 2003-09-23 US US10/668,521 patent/US7150874B2/en not_active Expired - Lifetime
-
2011
- 2011-07-22 JP JP2011160693A patent/JP2011234731A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20040228840A1 (en) | 2004-11-18 |
DK1180155T3 (da) | 2009-02-16 |
EP1180155A1 (de) | 2002-02-20 |
JP2011234731A (ja) | 2011-11-24 |
WO2000073476A1 (en) | 2000-12-07 |
CA2372709A1 (en) | 2000-12-07 |
JP2003501039A (ja) | 2003-01-14 |
US6682742B1 (en) | 2004-01-27 |
US7150874B2 (en) | 2006-12-19 |
EP1180155B1 (de) | 2008-10-29 |
JP5639736B2 (ja) | 2014-12-10 |
CA2372709C (en) | 2011-10-25 |
AU5397100A (en) | 2000-12-18 |
ATE412762T1 (de) | 2008-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |