DE60035424D1 - Neue enzyme und metabolite im skatol-stoffwechsel - Google Patents
Neue enzyme und metabolite im skatol-stoffwechselInfo
- Publication number
- DE60035424D1 DE60035424D1 DE60035424T DE60035424T DE60035424D1 DE 60035424 D1 DE60035424 D1 DE 60035424D1 DE 60035424 T DE60035424 T DE 60035424T DE 60035424 T DE60035424 T DE 60035424T DE 60035424 D1 DE60035424 D1 DE 60035424D1
- Authority
- DE
- Germany
- Prior art keywords
- metabolites
- enzymes
- skatole
- pigs
- skatole metabolism
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- ZFRKQXVRDFCRJG-UHFFFAOYSA-N skatole Chemical compound C1=CC=C2C(C)=CNC2=C1 ZFRKQXVRDFCRJG-UHFFFAOYSA-N 0.000 title abstract 13
- 102000004190 Enzymes Human genes 0.000 title abstract 7
- 108090000790 Enzymes Proteins 0.000 title abstract 7
- 239000002207 metabolite Substances 0.000 title abstract 4
- 239000004744 fabric Substances 0.000 title 1
- 229940074386 skatole Drugs 0.000 abstract 6
- 230000004060 metabolic process Effects 0.000 abstract 5
- BBZCPUCZKLTAJQ-UHFFFAOYSA-N 3-methyloxindole Chemical compound C1=CC=C2C(C)C(=O)NC2=C1 BBZCPUCZKLTAJQ-UHFFFAOYSA-N 0.000 abstract 4
- 241000282887 Suidae Species 0.000 abstract 3
- HEQOJEGTZCTHCF-UHFFFAOYSA-N 2-amino-1-phenylethanone Chemical compound NCC(=O)C1=CC=CC=C1 HEQOJEGTZCTHCF-UHFFFAOYSA-N 0.000 abstract 2
- 230000002708 enhancing effect Effects 0.000 abstract 2
- 108091023020 Aldehyde Oxidase Proteins 0.000 abstract 1
- 102000048262 Aldehyde oxidases Human genes 0.000 abstract 1
- 102100036194 Cytochrome P450 2A6 Human genes 0.000 abstract 1
- 101000875170 Homo sapiens Cytochrome P450 2A6 Proteins 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000010448 genetic screening Methods 0.000 abstract 1
- IVYPNXXAYMYVSP-UHFFFAOYSA-N indole-3-methanol Chemical compound C1=CC=C2C(CO)=CNC2=C1 IVYPNXXAYMYVSP-UHFFFAOYSA-N 0.000 abstract 1
- 238000007423 screening assay Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/108—Swine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/795—Porphyrin- or corrin-ring-containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/795—Porphyrin- or corrin-ring-containing peptides
- G01N2333/80—Cytochromes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/90245—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Chemical Or Physical Treatment Of Fibers (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15693599P | 1999-09-30 | 1999-09-30 | |
| PCT/CA2000/001129 WO2001023601A2 (en) | 1999-09-30 | 2000-09-29 | Novel enzymes and metabolites involved in skatole metabolism |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60035424D1 true DE60035424D1 (de) | 2007-08-16 |
Family
ID=22561713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60035424T Expired - Lifetime DE60035424D1 (de) | 1999-09-30 | 2000-09-29 | Neue enzyme und metabolite im skatol-stoffwechsel |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US6448028B1 (de) |
| EP (1) | EP1218534B1 (de) |
| AT (1) | ATE366322T1 (de) |
| AU (1) | AU781806B2 (de) |
| CA (1) | CA2383887A1 (de) |
| DE (1) | DE60035424D1 (de) |
| WO (1) | WO2001023601A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7329489B2 (en) | 2000-04-14 | 2008-02-12 | Matabolon, Inc. | Methods for drug discovery, disease treatment, and diagnosis using metabolomics |
| CA2443806A1 (en) | 2000-04-14 | 2002-10-25 | Metabolon, Inc. | Methods for drug discovery, disease treatment, and diagnosis using metabolomics |
| US20090221539A1 (en) * | 2005-12-15 | 2009-09-03 | University Of Guelph | Method of detecting and reducing boar taint using nuclear receptors |
| US8849577B2 (en) | 2006-09-15 | 2014-09-30 | Metabolon, Inc. | Methods of identifying biochemical pathways |
| CN107182927B (zh) * | 2017-06-20 | 2020-06-26 | 山东农业大学 | 一种优质型白猪配套系的育种方法 |
| FR3129727A1 (fr) * | 2021-11-29 | 2023-06-02 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Procédé de détection du scatol dans une solution aqueuse |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4906563A (en) * | 1987-12-28 | 1990-03-06 | Idetek, Inc. | Detection of skatole for meat quality |
| DK171085B1 (da) * | 1994-06-24 | 1996-05-28 | Slagteriernes Forskningsinst | Fremgangsmåde til at undersøge grise for at bestemme om de er egnet til avl eller formering samt anvendelse af dyr eller sæd |
| CA2234349A1 (en) * | 1998-04-08 | 1999-10-08 | University Of Guelph | Method of reducing boar taint |
-
2000
- 2000-09-29 AU AU75016/00A patent/AU781806B2/en not_active Ceased
- 2000-09-29 DE DE60035424T patent/DE60035424D1/de not_active Expired - Lifetime
- 2000-09-29 US US09/672,039 patent/US6448028B1/en not_active Expired - Lifetime
- 2000-09-29 AT AT00963835T patent/ATE366322T1/de not_active IP Right Cessation
- 2000-09-29 EP EP00963835A patent/EP1218534B1/de not_active Expired - Lifetime
- 2000-09-29 WO PCT/CA2000/001129 patent/WO2001023601A2/en active IP Right Grant
- 2000-09-29 CA CA002383887A patent/CA2383887A1/en not_active Abandoned
-
2002
- 2002-07-29 US US10/206,118 patent/US20020197663A1/en not_active Abandoned
-
2004
- 2004-04-12 US US10/555,800 patent/US20070031837A1/en not_active Abandoned
-
2006
- 2006-03-06 US US11/369,081 patent/US20060150263A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU781806B2 (en) | 2005-06-16 |
| WO2001023601A3 (en) | 2001-08-16 |
| US20070031837A1 (en) | 2007-02-08 |
| EP1218534A2 (de) | 2002-07-03 |
| AU7501600A (en) | 2001-04-30 |
| US6448028B1 (en) | 2002-09-10 |
| US20060150263A1 (en) | 2006-07-06 |
| CA2383887A1 (en) | 2001-04-05 |
| WO2001023601A2 (en) | 2001-04-05 |
| ATE366322T1 (de) | 2007-07-15 |
| EP1218534B1 (de) | 2007-07-04 |
| US20020197663A1 (en) | 2002-12-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8332 | No legal effect for de |