DE60030850D1 - Verfahren zur behandlung von tumoren mittels antiangiogener substanzen - Google Patents

Verfahren zur behandlung von tumoren mittels antiangiogener substanzen

Info

Publication number
DE60030850D1
DE60030850D1 DE60030850T DE60030850T DE60030850D1 DE 60030850 D1 DE60030850 D1 DE 60030850D1 DE 60030850 T DE60030850 T DE 60030850T DE 60030850 T DE60030850 T DE 60030850T DE 60030850 D1 DE60030850 D1 DE 60030850D1
Authority
DE
Germany
Prior art keywords
nucleic acid
antiangiogenic protein
recombinant nucleic
antiangiogenic
tumors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60030850T
Other languages
English (en)
Other versions
DE60030850T2 (de
Inventor
K Libutti
Andrew Feldman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Publication of DE60030850D1 publication Critical patent/DE60030850D1/de
Application granted granted Critical
Publication of DE60030850T2 publication Critical patent/DE60030850T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60030850T 1999-05-07 2000-05-05 Verfahren zur behandlung von tumoren mittels antiangiogener substanzen Expired - Fee Related DE60030850T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13324399P 1999-05-07 1999-05-07
US133243P 1999-05-07
PCT/US2000/012392 WO2000068379A1 (en) 1999-05-07 2000-05-05 Methods for treating tumors using antiangiogenic compounds

Publications (2)

Publication Number Publication Date
DE60030850D1 true DE60030850D1 (de) 2006-11-02
DE60030850T2 DE60030850T2 (de) 2007-09-20

Family

ID=22457666

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60030850T Expired - Fee Related DE60030850T2 (de) 1999-05-07 2000-05-05 Verfahren zur behandlung von tumoren mittels antiangiogener substanzen

Country Status (7)

Country Link
EP (1) EP1179061B1 (de)
JP (1) JP2003510015A (de)
AT (1) ATE340260T1 (de)
AU (1) AU781134B2 (de)
CA (1) CA2372699A1 (de)
DE (1) DE60030850T2 (de)
WO (1) WO2000068379A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020115202A1 (en) * 1999-08-13 2002-08-22 Paul Hallenbeck Adenoviral vectors including dna sequences encoding angiogenic inhibitors
EP1711172A4 (de) * 2003-12-23 2008-07-16 Univ Pennsylvania Zusammensetzungen und verfahren für die kombinationstherapie von erkrankungen
CN110664996B (zh) * 2019-11-04 2023-08-25 董红燕 Pedf来源的多肽复合物在制备治疗肺癌药物中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0689551B1 (de) * 1993-03-17 2008-02-20 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Immunogene chimäre umfassend nucleinsäuresequenzen, die signalsequenzpeptide des endoplasmatischen reticulums und mindestens ein anderes peptid codieren, deren verwendung in impfstoffen und zur behandlung von krankheiten
WO1997016169A1 (en) * 1995-11-01 1997-05-09 Chiron Corporation Treatment of a cardiovascular indication by delivery of therapeutics to the pericardial space
US5904144A (en) * 1996-03-22 1999-05-18 Cytotherapeutics, Inc. Method for treating ophthalmic diseases
CN1177934C (zh) * 1997-04-28 2004-12-01 阿文蒂斯药物股份有限公司 腺病毒介导的肿瘤内投送血管生成拮抗剂用于肿瘤的治疗
AU7471098A (en) * 1997-04-30 1998-11-24 Mount Sinai School Of Medicine Of The City University Of New York, The Recombinant influenza viruses expressing tumor-associated antigens as antitum or agents

Also Published As

Publication number Publication date
EP1179061B1 (de) 2006-09-20
WO2000068379A1 (en) 2000-11-16
CA2372699A1 (en) 2000-11-16
ATE340260T1 (de) 2006-10-15
AU781134B2 (en) 2005-05-05
DE60030850T2 (de) 2007-09-20
EP1179061A1 (de) 2002-02-13
JP2003510015A (ja) 2003-03-18
AU4824900A (en) 2000-11-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee