DE60030754D1 - Potenzierung der wirksamkeit von sn-38-prodrogen - Google Patents

Potenzierung der wirksamkeit von sn-38-prodrogen

Info

Publication number
DE60030754D1
DE60030754D1 DE60030754T DE60030754T DE60030754D1 DE 60030754 D1 DE60030754 D1 DE 60030754D1 DE 60030754 T DE60030754 T DE 60030754T DE 60030754 T DE60030754 T DE 60030754T DE 60030754 D1 DE60030754 D1 DE 60030754D1
Authority
DE
Germany
Prior art keywords
potentiating
prodrogen
efficacy
prodrug
polyanion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60030754T
Other languages
English (en)
Other versions
DE60030754T2 (de
Inventor
Sudhir Agrawal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aceragen Inc
Original Assignee
Hybridon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybridon Inc filed Critical Hybridon Inc
Application granted granted Critical
Publication of DE60030754D1 publication Critical patent/DE60030754D1/de
Publication of DE60030754T2 publication Critical patent/DE60030754T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60030754T 1999-11-09 2000-11-08 Potenzierung der wirksamkeit von sn-38-prodrogen Expired - Lifetime DE60030754T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16418299P 1999-11-09 1999-11-09
US164182P 1999-11-09
PCT/US2000/030687 WO2001034093A2 (en) 1999-11-09 2000-11-08 Potentiation of prodrug efficacy

Publications (2)

Publication Number Publication Date
DE60030754D1 true DE60030754D1 (de) 2006-10-26
DE60030754T2 DE60030754T2 (de) 2007-09-20

Family

ID=22593346

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60030754T Expired - Lifetime DE60030754T2 (de) 1999-11-09 2000-11-08 Potenzierung der wirksamkeit von sn-38-prodrogen

Country Status (7)

Country Link
EP (1) EP1229938B1 (de)
JP (1) JP2003513894A (de)
AT (1) ATE339212T1 (de)
AU (1) AU1474901A (de)
CA (1) CA2390975A1 (de)
DE (1) DE60030754T2 (de)
WO (1) WO2001034093A2 (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2207093A1 (en) * 1994-12-06 1996-06-13 Ryan Pharmaceuticals, Inc. Water soluble ubiquinone compositions, prodrugs, and methods relating thereto
GB9801902D0 (en) * 1998-01-29 1998-03-25 Cancer Res Campaign Tech A gene promoter

Also Published As

Publication number Publication date
WO2001034093A2 (en) 2001-05-17
JP2003513894A (ja) 2003-04-15
DE60030754T2 (de) 2007-09-20
CA2390975A1 (en) 2001-05-17
EP1229938A2 (de) 2002-08-14
ATE339212T1 (de) 2006-10-15
AU1474901A (en) 2001-06-06
EP1229938B1 (de) 2006-09-13
WO2001034093A3 (en) 2001-11-22

Similar Documents

Publication Publication Date Title
NO20014128D0 (no) Camptothecinderivater som har antitumoraktivitet
DE60022714D1 (de) Implantierbarer Herzschrittmacher
DK1268481T3 (da) Inaseinkibitorer som terapeutiske midler
ES2138271T3 (es) Compuestos de 6-dimetil-amino-metil-1-fenil-ciclohexano como principio activo farmaceutico.
PT1355889E (pt) Derivados diamina triazole substituidos como inibidores de cinase
DE60108581D1 (de) Implantierbarer Herzschrittmacher
DE69919787D1 (de) Multi-Ort, parameter- gesteuerter, implantierbarer Herzschrittmacher / Defribrillator
ZA200108012B (en) Method of enhancing the efficacy of anti-tumor agents.
EA199900912A1 (ru) Фармацевтические средства
IT1302682B1 (it) Composizioni farmaceutiche orali contenenti buprenorfina
MXPA03007903A (es) Sistema terapeutico transdermico altamente flexible con nicotina como ingrediente activo.
WO2001046455A3 (en) Survivin promotion of angiogenesis
DK1696911T3 (da) Intranasale sammensætninger
DE69941825D1 (de) Arzneistoffhaltiger kaugummi, dessen herstellungsverfahren und so erhaltene tablette
TR200400354T4 (tr) Fenil ikameli indolizin türevleri ve bunların histamin H3 ligandları olarak kullanımı
DE50003566D1 (de) Haftvermittler
WO2001030330A3 (en) Method to treat pain utilizing benzimidazole nmda/nr2b antagonists
EE200300129A (et) Distamütsiini alfa-halogenoakrüloüülderivaadi kasutamine
ITMI20031714A1 (it) Formazioni ad azione antitumorale.
DE59911871D1 (de) Zweikammer-Herzschrittmacher
ITPR20020027A1 (it) Ampolla nebulizzatrice, in particolare per aerosolterapia.
DE60030754D1 (de) Potenzierung der wirksamkeit von sn-38-prodrogen
DE69916133D1 (de) Elektro-neuro-adaptiver stimulator
ATE504302T1 (de) Methoden zur verminderung oder verhinderung von schmerzen mit spicamycin-derivaten
TW200501952A (en) Pirfenidone gel formulations

Legal Events

Date Code Title Description
8364 No opposition during term of opposition