DE60030587D1 - Mit bh4 fusionierte polypeptide - Google Patents

Mit bh4 fusionierte polypeptide

Info

Publication number
DE60030587D1
DE60030587D1 DE60030587T DE60030587T DE60030587D1 DE 60030587 D1 DE60030587 D1 DE 60030587D1 DE 60030587 T DE60030587 T DE 60030587T DE 60030587 T DE60030587 T DE 60030587T DE 60030587 D1 DE60030587 D1 DE 60030587D1
Authority
DE
Germany
Prior art keywords
amino acid
acid sequence
apoptosis
ischemic disease
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60030587T
Other languages
English (en)
Other versions
DE60030587T2 (de
Inventor
Shigeomi Shimizu
Yoshihide Tsujimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of DE60030587D1 publication Critical patent/DE60030587D1/de
Application granted granted Critical
Publication of DE60030587T2 publication Critical patent/DE60030587T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
DE60030587T 1999-12-27 2000-12-26 Mit bh4 fusionierte polypeptide Expired - Fee Related DE60030587T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP37144999 1999-12-27
JP37144999 1999-12-27
PCT/JP2000/009274 WO2001048014A1 (fr) 1999-12-27 2000-12-26 Polypeptides bh4-fusionnes

Publications (2)

Publication Number Publication Date
DE60030587D1 true DE60030587D1 (de) 2006-10-19
DE60030587T2 DE60030587T2 (de) 2007-05-31

Family

ID=18498735

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60030587T Expired - Fee Related DE60030587T2 (de) 1999-12-27 2000-12-26 Mit bh4 fusionierte polypeptide

Country Status (6)

Country Link
US (1) US20030152946A1 (de)
EP (1) EP1243595B1 (de)
JP (1) JP3906078B2 (de)
AT (1) ATE338770T1 (de)
DE (1) DE60030587T2 (de)
WO (1) WO2001048014A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030077826A1 (en) * 2001-02-02 2003-04-24 Lena Edelman Chimeric molecules containing a module able to target specific cells and a module regulating the apoptogenic function of the permeability transition pore complex (PTPC)
MX348062B (es) * 2003-05-16 2017-05-26 Acorda Therapeutics Inc Mutantes que degradan proteoglicanos para tratamiento del snc.
FR2860237B1 (fr) 2003-09-30 2006-03-10 Centre Nat Rech Scient Polypeptide d'interaction comprenant un motif heptapeptidique et un domaine de penetration cellulaire
US20070154962A1 (en) * 2005-12-23 2007-07-05 Giulio Taglialatela Bcl-2 promoted cell death
JP2012513218A (ja) * 2008-12-23 2012-06-14 ヴィヴォスクリプト，インコーポレイテッド 遺伝子改変を伴わずに細胞を再プログラミングするための組成物および方法
WO2016018454A2 (en) * 2014-06-18 2016-02-04 Cisthera, Inc. Compositions and methods employing bcl2 and bcl2 family members
WO2017189826A1 (en) * 2016-04-29 2017-11-02 Portage Pharmaceuticals Ltd. Use of cell-permeable peptides and non-peptide carriers conjugated with nemo binding domain cargo sequence for the treatment of dry eye disease and uveitis
MX2020001232A (es) 2017-08-01 2020-03-20 O&M Halyard Int Unlimited Co Sistema de bolsillo y manta para proporcionar campos esteriles.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646008A (en) * 1993-06-22 1997-07-08 The Regent Of The University Of Michigan Vertebrate apoptosis gene: compositions and methods

Also Published As

Publication number Publication date
WO2001048014A1 (fr) 2001-07-05
JP3906078B2 (ja) 2007-04-18
EP1243595A4 (de) 2004-08-04
EP1243595A1 (de) 2002-09-25
EP1243595B1 (de) 2006-09-06
DE60030587T2 (de) 2007-05-31
ATE338770T1 (de) 2006-09-15
US20030152946A1 (en) 2003-08-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee