DE60030428D1 - 4-cyano-3-hydroxy-butanoyl hydrazine, derivate und verfahren zu ihrer herstellung - Google Patents

4-cyano-3-hydroxy-butanoyl hydrazine, derivate und verfahren zu ihrer herstellung

Info

Publication number
DE60030428D1
DE60030428D1 DE60030428T DE60030428T DE60030428D1 DE 60030428 D1 DE60030428 D1 DE 60030428D1 DE 60030428 T DE60030428 T DE 60030428T DE 60030428 T DE60030428 T DE 60030428T DE 60030428 D1 DE60030428 D1 DE 60030428D1
Authority
DE
Germany
Prior art keywords
cyano
hydroxy
butanoyl
hydrazine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60030428T
Other languages
English (en)
Other versions
DE60030428T2 (de
Inventor
Rawle I Hollingsworth
Guijun Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Michigan State University MSU
Original Assignee
Michigan State University MSU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Michigan State University MSU filed Critical Michigan State University MSU
Application granted granted Critical
Publication of DE60030428D1 publication Critical patent/DE60030428D1/de
Publication of DE60030428T2 publication Critical patent/DE60030428T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/34—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a carbon skeleton further substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/19—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton
    • C07C255/20—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60030428T 1999-05-24 2000-04-25 4-cyano-3-hydroxy-butanoyl hydrazine, derivate und verfahren zu ihrer herstellung Expired - Fee Related DE60030428T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US317398 1989-03-01
US09/317,398 US6114566A (en) 1999-05-24 1999-05-24 4-cyano-3-hydroxybutanoyl hydrazines, derivatives and process for the preparation thereof
PCT/US2000/011124 WO2000071503A1 (en) 1999-05-24 2000-04-25 4-cyano-3-hydroxy butanoyl hydrazines, derivatives and process for the preparation thereof

Publications (2)

Publication Number Publication Date
DE60030428D1 true DE60030428D1 (de) 2006-10-12
DE60030428T2 DE60030428T2 (de) 2006-12-21

Family

ID=23233465

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60030428T Expired - Fee Related DE60030428T2 (de) 1999-05-24 2000-04-25 4-cyano-3-hydroxy-butanoyl hydrazine, derivate und verfahren zu ihrer herstellung

Country Status (9)

Country Link
US (1) US6114566A (de)
EP (1) EP1180095B1 (de)
JP (1) JP3759411B2 (de)
KR (1) KR100472806B1 (de)
AT (1) ATE338026T1 (de)
AU (1) AU4662900A (de)
CA (1) CA2365859C (de)
DE (1) DE60030428T2 (de)
WO (1) WO2000071503A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100255039B1 (ko) * 1997-07-28 2000-05-01 박영구 L-카르니틴의제조방법
US6884607B2 (en) 2000-12-07 2005-04-26 Sumitomo Chemical Company, Limited Process for producing optically active 4-halo-3-hydroxybutanoate
CN1688539A (zh) * 2002-10-03 2005-10-26 Sk能量及化学公司 一种合成子的改进合成方法
CN102076331B (zh) * 2008-06-26 2013-12-18 普罗林科斯有限责任公司 具有可控的药物释放速率的前药和药物-大分子轭合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2049536C (en) * 1991-05-13 1999-07-06 Rawle I. Hollingsworth Process for the preparation of 3,4-dihydroxybutanoic acid and salts thereof
US6084131A (en) * 1998-06-01 2000-07-04 Board Of Trustees Operating Michigan State University Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof

Also Published As

Publication number Publication date
KR20010105381A (ko) 2001-11-28
EP1180095A1 (de) 2002-02-20
DE60030428T2 (de) 2006-12-21
CA2365859A1 (en) 2000-11-30
EP1180095B1 (de) 2006-08-30
ATE338026T1 (de) 2006-09-15
US6114566A (en) 2000-09-05
JP2003500379A (ja) 2003-01-07
CA2365859C (en) 2004-11-30
KR100472806B1 (ko) 2005-03-08
WO2000071503A1 (en) 2000-11-30
JP3759411B2 (ja) 2006-03-22
AU4662900A (en) 2000-12-12
EP1180095A4 (de) 2005-01-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee