DE60025026D1 - Antimicrobielle wirkung des ersten kationischen cluster des menschlichen lactoferrins - Google Patents

Antimicrobielle wirkung des ersten kationischen cluster des menschlichen lactoferrins

Info

Publication number
DE60025026D1
DE60025026D1 DE60025026T DE60025026T DE60025026D1 DE 60025026 D1 DE60025026 D1 DE 60025026D1 DE 60025026 T DE60025026 T DE 60025026T DE 60025026 T DE60025026 T DE 60025026T DE 60025026 D1 DE60025026 D1 DE 60025026D1
Authority
DE
Germany
Prior art keywords
human lactoferrin
antimicrobial effect
polypeptides
cluster
cationic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60025026T
Other languages
English (en)
Other versions
DE60025026T2 (de
Inventor
Berkel Hendrikus Van
Hendrikus Nibbering
Henricus Nuijens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AM Pharma BV
Original Assignee
AM Pharma BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AM Pharma BV filed Critical AM Pharma BV
Application granted granted Critical
Publication of DE60025026D1 publication Critical patent/DE60025026D1/de
Publication of DE60025026T2 publication Critical patent/DE60025026T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE60025026T 1999-11-11 2000-11-10 Antimikrobielle Wirkung des ersten kationischen Clusters des menschlichen Lactoferrins Expired - Lifetime DE60025026T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US16497599P 1999-11-11 1999-11-11
EP99203775 1999-11-11
US164975P 1999-11-11
EP99203775 1999-11-11
PCT/NL2000/000821 WO2001034641A2 (en) 1999-11-11 2000-11-10 Antimicrobial activity of the first cationic cluster of human lactoferrin

Publications (2)

Publication Number Publication Date
DE60025026D1 true DE60025026D1 (de) 2006-01-26
DE60025026T2 DE60025026T2 (de) 2006-08-03

Family

ID=26153390

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60025026T Expired - Lifetime DE60025026T2 (de) 1999-11-11 2000-11-10 Antimikrobielle Wirkung des ersten kationischen Clusters des menschlichen Lactoferrins

Country Status (11)

Country Link
EP (1) EP1228097B1 (de)
JP (1) JP2003521483A (de)
AT (1) ATE313562T1 (de)
AU (1) AU776044B2 (de)
CA (1) CA2388910C (de)
CY (1) CY1105008T1 (de)
DE (1) DE60025026T2 (de)
DK (1) DK1228097T3 (de)
ES (1) ES2256070T3 (de)
PT (1) PT1228097E (de)
WO (1) WO2001034641A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4486501A (en) * 2000-03-27 2001-10-08 Pharming Intellectual Property Bv High dosage parenteral administration of lactoferrin
US6812221B2 (en) 2000-11-21 2004-11-02 The Texas A&M University System FGF-affinity chromatography
EP1360961A1 (de) * 2002-05-07 2003-11-12 AM-Pharma B.V. Verwendung von antimikrobiell wirkenden Peptiden zur Aktivitätssteigerung von antimikrobiellen Wirkstoffen
CN1852728A (zh) * 2003-07-16 2006-10-25 纽约州州立大学研究基金会 宿主防御因子x(hdfx)
WO2007055578A1 (en) * 2005-11-11 2007-05-18 Leids Universitair Medisch Centrum Cyclic antimicrobial peptides derived from lactoferrin
CA2657543C (en) * 2006-07-10 2017-03-07 Osterreichische Akademie Der Wissenschaften Antimicrobial peptides
EP2030980A1 (de) * 2007-08-28 2009-03-04 AM-Pharma B.V. Lactoferrin-Mutanten
EP2050461A1 (de) 2007-10-19 2009-04-22 PharmaSurgics in Sweden AB Peptide basierend auf der menschlichen Lactoferrinsequenz und ihre Verwendung
EP2060586A1 (de) * 2007-11-14 2009-05-20 PharmaSurgics in Sweden AB Neue synthetische Arginin-substituierte Peptide und ihre Verwendung
EP2481751A1 (de) 2011-01-26 2012-08-01 PharmaSurgics in Sweden AB Humanem Lactoferrin abgeleitete Peptide
JP6099055B2 (ja) * 2014-05-09 2017-03-22 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 変性病変の診断のためのリガンドとしてのフコイダン
CN107304424B (zh) 2016-05-23 2019-05-10 成都福际生物技术有限公司 改造的转铁蛋白dna结合域、重组dna聚合酶及制备方法
EP3737750B1 (de) 2018-01-09 2024-06-05 Theriva Biologics, Inc. Alkalische phosphatasemittel zur behandlung von entwicklungsstörungen des nervensystems
CA3094173A1 (en) 2018-03-20 2019-09-26 Synthetic Biologics, Inc. Intestinal alkaline phosphatase formulations
CA3094174A1 (en) 2018-03-20 2019-09-26 Synthetic Biologics, Inc. Alkaline phosphatase agents for treatment of radiation disorders
EP4137511A4 (de) * 2020-04-16 2024-01-10 Dermopartners S L Neue zusammensetzung zur verwendung zur behandlung und prävention von infektionen durch covid-19 und andere coronaviren

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993014640A1 (en) * 1992-01-23 1993-08-05 Morinaga Milk Industry Co., Ltd. Antibacterial agent and treatment of article therewith
DE69524386D1 (de) * 1994-02-16 2002-01-17 Pharming Intellectual Pty Bv Isolierung von lactoferrin aus milch
JP3506274B2 (ja) * 1994-09-01 2004-03-15 雪印乳業株式会社 新規ペプチドおよび免疫賦活剤
JPH1192375A (ja) * 1997-09-25 1999-04-06 Morinaga Milk Ind Co Ltd ニューキノロン系抗菌剤の抗菌性を増強させる抗菌剤

Also Published As

Publication number Publication date
ES2256070T3 (es) 2006-07-16
JP2003521483A (ja) 2003-07-15
WO2001034641A3 (en) 2002-02-14
EP1228097A2 (de) 2002-08-07
CA2388910A1 (en) 2001-05-17
PT1228097E (pt) 2006-05-31
ATE313562T1 (de) 2006-01-15
AU776044B2 (en) 2004-08-26
AU1901501A (en) 2001-06-06
CY1105008T1 (el) 2009-11-04
EP1228097B1 (de) 2005-12-21
DE60025026T2 (de) 2006-08-03
WO2001034641A8 (en) 2002-05-10
WO2001034641A2 (en) 2001-05-17
CA2388910C (en) 2008-10-07
DK1228097T3 (da) 2006-04-18

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