DE60012163D1 - Verwendung von ap-1 aktivatoren zur behandlung von glaukom und erhöhtem augenblutdruck - Google Patents

Verwendung von ap-1 aktivatoren zur behandlung von glaukom und erhöhtem augenblutdruck

Info

Publication number
DE60012163D1
DE60012163D1 DE60012163T DE60012163T DE60012163D1 DE 60012163 D1 DE60012163 D1 DE 60012163D1 DE 60012163 T DE60012163 T DE 60012163T DE 60012163 T DE60012163 T DE 60012163T DE 60012163 D1 DE60012163 D1 DE 60012163D1
Authority
DE
Germany
Prior art keywords
activators
glaucoma
treatment
blood pressure
increased eye
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60012163T
Other languages
English (en)
Other versions
DE60012163T2 (de
Inventor
L Shade
Iok-Hou Pang
F Clark
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Research LLC
Original Assignee
Alcon Manufacturing Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Manufacturing Ltd filed Critical Alcon Manufacturing Ltd
Application granted granted Critical
Publication of DE60012163D1 publication Critical patent/DE60012163D1/de
Publication of DE60012163T2 publication Critical patent/DE60012163T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
DE60012163T 1999-04-20 2000-04-07 Verwendung von ap-1 aktivatoren zur behandlung von glaukom und erhöhtem augenblutdruck Expired - Fee Related DE60012163T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13013399P 1999-04-20 1999-04-20
US130133P 1999-04-20
PCT/US2000/009503 WO2000062769A2 (en) 1999-04-20 2000-04-07 Use of ap-1 activators to treat glaucoma and ocular hypertension

Publications (2)

Publication Number Publication Date
DE60012163D1 true DE60012163D1 (de) 2004-08-19
DE60012163T2 DE60012163T2 (de) 2004-11-11

Family

ID=22443214

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60012163T Expired - Fee Related DE60012163T2 (de) 1999-04-20 2000-04-07 Verwendung von ap-1 aktivatoren zur behandlung von glaukom und erhöhtem augenblutdruck

Country Status (12)

Country Link
EP (1) EP1169026B1 (de)
JP (1) JP2002542189A (de)
AT (1) ATE270883T1 (de)
AU (1) AU766199B2 (de)
BR (1) BR0009862A (de)
CA (1) CA2369126A1 (de)
DE (1) DE60012163T2 (de)
DK (1) DK1169026T3 (de)
ES (1) ES2223502T3 (de)
HK (1) HK1039568B (de)
PT (1) PT1169026E (de)
WO (1) WO2000062769A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010000851A2 (en) * 2008-07-04 2010-01-07 Institut National De La Sante Et De La Recherche Medicale (Inserm) Methods for modulating angiogenesis via dystrophin dp71

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981568A (en) * 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
CN1169857A (zh) * 1996-07-10 1998-01-14 林东和 降眼压活性组合物

Also Published As

Publication number Publication date
DE60012163T2 (de) 2004-11-11
ES2223502T3 (es) 2005-03-01
DK1169026T3 (da) 2004-10-04
BR0009862A (pt) 2002-01-08
EP1169026B1 (de) 2004-07-14
PT1169026E (pt) 2004-10-29
JP2002542189A (ja) 2002-12-10
HK1039568A1 (en) 2002-05-03
AU4223100A (en) 2000-11-02
ATE270883T1 (de) 2004-07-15
WO2000062769A2 (en) 2000-10-26
WO2000062769A3 (en) 2001-01-04
AU766199B2 (en) 2003-10-09
EP1169026A2 (de) 2002-01-09
HK1039568B (zh) 2004-12-10
CA2369126A1 (en) 2000-10-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee