DE60008415D1 - Zusammensetzung die mindestens ein stickstoffmonoxid-synthase inhibitor und mindestens ein phospholipase a2 inhibitor enthält zur herstellung eines medikamentes - Google Patents

Zusammensetzung die mindestens ein stickstoffmonoxid-synthase inhibitor und mindestens ein phospholipase a2 inhibitor enthält zur herstellung eines medikamentes

Info

Publication number
DE60008415D1
DE60008415D1 DE60008415T DE60008415T DE60008415D1 DE 60008415 D1 DE60008415 D1 DE 60008415D1 DE 60008415 T DE60008415 T DE 60008415T DE 60008415 T DE60008415 T DE 60008415T DE 60008415 D1 DE60008415 D1 DE 60008415D1
Authority
DE
Germany
Prior art keywords
inhibitor
phospholipase
nitrogen monoxide
production
composition containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60008415T
Other languages
English (en)
Other versions
DE60008415T2 (de
Inventor
Michel Auguet
De Lassauniere Pierre Chabrier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Application granted granted Critical
Publication of DE60008415D1 publication Critical patent/DE60008415D1/de
Publication of DE60008415T2 publication Critical patent/DE60008415T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/12—Antivirals
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Otolaryngology (AREA)
  • Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
DE60008415T 1999-11-05 2000-11-03 Zusammensetzung, die mindestens eine Stickstoffmonoxid-Synthase hemmende Substanz in Verbindung mit mindestens einer Phospholipase A2 hemmenden Substanz enthält zur Herstellung eines Medikaments Expired - Lifetime DE60008415T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9913859A FR2800615B1 (fr) 1999-11-05 1999-11-05 Produit comprenant au moins une substance inhibitrice des no synthases en association avec au moins une substance inhibitrice des phospholipases a2
FR9913859 1999-11-05
PCT/FR2000/003066 WO2001032216A2 (fr) 1999-11-05 2000-11-03 Produit comprenant au moins une substance inhibitrice des no synthases en association avec au moins une substance inhibitrice des phospholipases a2

Publications (2)

Publication Number Publication Date
DE60008415D1 true DE60008415D1 (de) 2004-03-25
DE60008415T2 DE60008415T2 (de) 2004-12-16

Family

ID=9551744

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60008415T Expired - Lifetime DE60008415T2 (de) 1999-11-05 2000-11-03 Zusammensetzung, die mindestens eine Stickstoffmonoxid-Synthase hemmende Substanz in Verbindung mit mindestens einer Phospholipase A2 hemmenden Substanz enthält zur Herstellung eines Medikaments

Country Status (16)

Country Link
US (1) US6872738B1 (de)
EP (1) EP1233786B1 (de)
JP (1) JP2003513050A (de)
AT (1) ATE259659T1 (de)
AU (1) AU1287001A (de)
CA (1) CA2389661A1 (de)
CZ (1) CZ20021549A3 (de)
DE (1) DE60008415T2 (de)
DK (1) DK1233786T3 (de)
ES (1) ES2215746T3 (de)
FR (1) FR2800615B1 (de)
HU (1) HUP0203348A3 (de)
PL (1) PL202997B1 (de)
PT (1) PT1233786E (de)
RU (1) RU2256465C2 (de)
WO (1) WO2001032216A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU228783B1 (en) * 2001-07-26 2013-05-28 Greenearth Cleaning Dry cleaning apparatus and method capable of utilizing a siloxane solvent
US8586516B2 (en) * 2007-01-19 2013-11-19 Afton Chemical Corporation High TBN / low phosphorus economic STUO lubricants
CN113730409B (zh) * 2021-11-01 2022-06-14 济南市中心医院 奎纳克林在制备治疗肺纤维化药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6335445B1 (en) * 1997-03-24 2002-01-01 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DK1233786T3 (da) 2004-06-21
HUP0203348A3 (en) 2005-03-29
DE60008415T2 (de) 2004-12-16
EP1233786A2 (de) 2002-08-28
WO2001032216A3 (fr) 2002-03-28
JP2003513050A (ja) 2003-04-08
WO2001032216A2 (fr) 2001-05-10
EP1233786B1 (de) 2004-02-18
CA2389661A1 (fr) 2001-05-10
FR2800615B1 (fr) 2002-05-03
RU2256465C2 (ru) 2005-07-20
AU1287001A (en) 2001-05-14
PL355285A1 (en) 2004-04-05
ATE259659T1 (de) 2004-03-15
US6872738B1 (en) 2005-03-29
HUP0203348A2 (hu) 2003-02-28
CZ20021549A3 (cs) 2002-11-13
PL202997B1 (pl) 2009-08-31
RU2002114694A (ru) 2004-01-10
FR2800615A1 (fr) 2001-05-11
PT1233786E (pt) 2004-07-30
ES2215746T3 (es) 2004-10-16

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Owner name: IPSEN PHARMA S.A.S., BOULOGNE-BILLANCOURT, FR