DE60003438D1 - Verfahren zur bereitung einer formulierung zur verzögerten freisetzung - Google Patents

Verfahren zur bereitung einer formulierung zur verzögerten freisetzung

Info

Publication number
DE60003438D1
DE60003438D1 DE60003438T DE60003438T DE60003438D1 DE 60003438 D1 DE60003438 D1 DE 60003438D1 DE 60003438 T DE60003438 T DE 60003438T DE 60003438 T DE60003438 T DE 60003438T DE 60003438 D1 DE60003438 D1 DE 60003438D1
Authority
DE
Germany
Prior art keywords
preparing
delayed release
release formula
formula
delayed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60003438T
Other languages
English (en)
Other versions
DE60003438T2 (de
Inventor
Thomas Ciaran Loughman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Manufacturing Ireland Ltd
Original Assignee
Kinerton Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kinerton Ltd filed Critical Kinerton Ltd
Publication of DE60003438D1 publication Critical patent/DE60003438D1/de
Application granted granted Critical
Publication of DE60003438T2 publication Critical patent/DE60003438T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6927—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Polyesters Or Polycarbonates (AREA)
DE60003438T 1999-08-18 2000-08-14 Verfahren zur bereitung einer formulierung zur verzögerten freisetzung Expired - Lifetime DE60003438T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IE19990700A IES990700A2 (en) 1999-08-18 1999-08-18 Process to make a sustained release formulation
IE990700 1999-08-18
PCT/IE2000/000099 WO2001012232A2 (en) 1999-08-18 2000-08-14 Process to make a sustained release formulation

Publications (2)

Publication Number Publication Date
DE60003438D1 true DE60003438D1 (de) 2003-07-24
DE60003438T2 DE60003438T2 (de) 2004-05-06

Family

ID=11042112

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60003438T Expired - Lifetime DE60003438T2 (de) 1999-08-18 2000-08-14 Verfahren zur bereitung einer formulierung zur verzögerten freisetzung

Country Status (26)

Country Link
US (1) US6893645B1 (de)
EP (1) EP1212095B1 (de)
JP (1) JP3730917B2 (de)
CN (2) CN1823736A (de)
AR (1) AR022647A1 (de)
AT (1) ATE243044T1 (de)
AU (1) AU755229B2 (de)
BR (1) BR0013349A (de)
CA (1) CA2380902C (de)
CZ (1) CZ294433B6 (de)
DE (1) DE60003438T2 (de)
DK (1) DK1212095T3 (de)
ES (1) ES2195925T3 (de)
HK (1) HK1044285A1 (de)
HU (1) HUP0202895A3 (de)
IE (1) IES990700A2 (de)
IL (1) IL148044A0 (de)
MX (1) MXPA02001415A (de)
NO (1) NO20020762L (de)
NZ (1) NZ517251A (de)
PL (1) PL199862B1 (de)
PT (1) PT1212095E (de)
RU (1) RU2211694C1 (de)
TW (1) TWI230069B (de)
WO (1) WO2001012232A2 (de)
ZA (1) ZA200202027B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1348444B1 (de) * 1999-08-18 2006-04-12 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Zusammensetzung mit verzögerter Abgabe in der ein Peptid mit einem Polymer komplexiert ist
EP1204429B1 (de) * 1999-08-18 2003-10-29 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Formulierung zur verzögerten freisetzung von peptiden
US7109166B1 (en) 1999-08-18 2006-09-19 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Sustained release formulation of a peptide
WO2005061088A1 (en) * 2003-12-22 2005-07-07 Finlay Warren H Powder formation by atmospheric spray-freeze drying
EP2446894A3 (de) 2004-10-27 2013-02-20 University Of Denver Analoga des adrenocorticotropen Hormons und entsprechende Verfahren

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221958B1 (en) 1993-01-06 2001-04-24 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
US5863985A (en) * 1995-06-29 1999-01-26 Kinerton Limited Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
EP0678018B1 (de) * 1993-01-06 2003-04-09 Kinerton Limited Ionische molekularkonjugate von bioabbaubaren polyestern und bioaktiven polypeptiden
ES2229045T3 (es) * 1993-08-09 2005-04-16 Sod Conseils Rech Applic Derivados de peptidos terapeuticos.
IE960308A1 (en) * 1996-04-23 1997-11-05 Kinerton Ltd Sustained release ionic conjugate
AU3215597A (en) * 1996-08-30 1998-03-19 Biomeasure Incorporated Method of inhibiting fibrosis with a somatostatin agonist
US5972893A (en) * 1997-05-06 1999-10-26 Cedars-Sinai Medical Center Method of treating hyperprolactinemia and prolactinomas
HUP0102373A2 (hu) 1998-01-29 2001-10-28 Kinerton Limited Eljárás abszorbeálódó mikrorészecskék előállítására
WO2000012232A1 (fr) 1998-08-28 2000-03-09 Mitutoyo Corporation Laveuse automatique de pieces pour intervention prealable dans un systeme de mesure et de production automatique equipe de ladite laveuse
EP1204429B1 (de) * 1999-08-18 2003-10-29 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Formulierung zur verzögerten freisetzung von peptiden

Also Published As

Publication number Publication date
WO2001012232A8 (en) 2002-06-06
ES2195925T3 (es) 2003-12-16
HK1044285A1 (en) 2002-10-18
AU6464700A (en) 2001-03-13
HUP0202895A2 (hu) 2003-02-28
CZ2002266A3 (cs) 2002-05-15
NZ517251A (en) 2003-08-29
RU2211694C1 (ru) 2003-09-10
US6893645B1 (en) 2005-05-17
IL148044A0 (en) 2002-09-12
NO20020762L (no) 2002-04-16
NO20020762D0 (no) 2002-02-15
PL354263A1 (en) 2003-12-29
JP2003507346A (ja) 2003-02-25
AU755229B2 (en) 2002-12-05
BR0013349A (pt) 2002-04-23
CA2380902A1 (en) 2001-02-22
CZ294433B6 (cs) 2005-01-12
TWI230069B (en) 2005-04-01
CN1377283A (zh) 2002-10-30
CN1246040C (zh) 2006-03-22
EP1212095B1 (de) 2003-06-18
MXPA02001415A (es) 2002-08-12
IES990700A2 (en) 2001-08-22
PT1212095E (pt) 2003-10-31
CA2380902C (en) 2008-08-05
WO2001012232A3 (en) 2002-04-04
RU2002106809A (ru) 2004-01-20
WO2001012232A2 (en) 2001-02-22
CN1823736A (zh) 2006-08-30
EP1212095A2 (de) 2002-06-12
ATE243044T1 (de) 2003-07-15
JP3730917B2 (ja) 2006-01-05
DK1212095T3 (da) 2003-10-06
DE60003438T2 (de) 2004-05-06
PL199862B1 (pl) 2008-11-28
AR022647A1 (es) 2002-09-04
ZA200202027B (en) 2002-12-24
HUP0202895A3 (en) 2003-11-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: IPSEN MANUFACTURING IRELAND LTD., DUBLIN, IE