DE60000556D1 - Tetrazolylalkyl-Indolderivate als entzündungshemmende und analgetische Mittel - Google Patents

Tetrazolylalkyl-Indolderivate als entzündungshemmende und analgetische Mittel

Info

Publication number
DE60000556D1
DE60000556D1 DE60000556T DE60000556T DE60000556D1 DE 60000556 D1 DE60000556 D1 DE 60000556D1 DE 60000556 T DE60000556 T DE 60000556T DE 60000556 T DE60000556 T DE 60000556T DE 60000556 D1 DE60000556 D1 DE 60000556D1
Authority
DE
Germany
Prior art keywords
alkyl
optionally substituted
tetrazolylalkyl
inflammatory
fully
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60000556T
Other languages
English (en)
Other versions
DE60000556T2 (de
Inventor
Kazunari Nakao
Rodney William Stevens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE60000556D1 publication Critical patent/DE60000556D1/de
Publication of DE60000556T2 publication Critical patent/DE60000556T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE60000556T 1999-07-02 2000-06-26 Tetrazolylalkyl-Indolderivate als entzündungshemmende und analgetische Mittel Expired - Fee Related DE60000556T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IB9901244 1999-07-02

Publications (2)

Publication Number Publication Date
DE60000556D1 true DE60000556D1 (de) 2002-11-14
DE60000556T2 DE60000556T2 (de) 2003-02-13

Family

ID=11004873

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60000556T Expired - Fee Related DE60000556T2 (de) 1999-07-02 2000-06-26 Tetrazolylalkyl-Indolderivate als entzündungshemmende und analgetische Mittel

Country Status (9)

Country Link
EP (1) EP1065206B1 (de)
JP (1) JP3337209B2 (de)
AT (1) ATE225785T1 (de)
BR (1) BR0002935A (de)
CA (1) CA2313106C (de)
DE (1) DE60000556T2 (de)
DK (1) DK1065206T3 (de)
ES (1) ES2182755T3 (de)
PT (1) PT1065206E (de)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ222878A (en) * 1986-12-17 1991-02-26 Merck Frosst Canada Inc 3-hetero-substituted-n-benzyl-indole derivatives, and pharmaceutical compositions
AP9801302A0 (en) * 1997-07-23 2000-01-23 Pfizer Indole compounds as anti-inflammatory/analgesic agents..
AP869A (en) * 1998-01-05 2000-09-04 Pfizer 2,3-Substituted indole compounds as anti-inflammatory and analgesic agents.

Also Published As

Publication number Publication date
JP2001031676A (ja) 2001-02-06
BR0002935A (pt) 2001-04-03
DE60000556T2 (de) 2003-02-13
PT1065206E (pt) 2003-01-31
EP1065206A1 (de) 2001-01-03
CA2313106C (en) 2004-07-13
EP1065206B1 (de) 2002-10-09
ATE225785T1 (de) 2002-10-15
DK1065206T3 (da) 2002-10-28
ES2182755T3 (es) 2003-03-16
CA2313106A1 (en) 2001-01-02
JP3337209B2 (ja) 2002-10-21

Similar Documents

Publication Publication Date Title
DK2314582T3 (da) Heterocykliske forbindelser som antivirusmidler
ATE215945T1 (de) Bicyclische carbonyl-indolverbindungen als entzündungshemmende/ analgetische wirkstoffe und als cox-2 inhibitoren
CY1105035T1 (el) Συγχωνευμενα με αρυλιο ή ετεροαρυλιο παραγωγα της ιμιδαζολης ως αντιφλεγμονωδεις και αναλγητικοι παραγοντες
ATE476431T1 (de) Piperidin- und azetidinderivate als glyt1- inhibitoren
SE0301446D0 (sv) New Compounds
PT992509E (pt) Novos derivados macrolidos
DE60101137D1 (de) N-Benzensulfonyl-L-Prolin Derivate und deren Verwendung als Bradykinin Antagonisten
DK1106614T3 (da) 5-leddede, heteroarylsubstituerede 1,4-dihydropyridinforbindelser som bradykininantagonister
DE60000556T2 (de) Tetrazolylalkyl-Indolderivate als entzündungshemmende und analgetische Mittel
DE60210981D1 (de) Heteroarylheteroalkylamin derivate und deren verwendung als inhibitoren der stickoxidsynthase
ATE258934T1 (de) Azaindol derivate und ihre verwendung als antithrombotische wirkstoffe
TW366283B (en) Compounds for treatment of arrhythmia
DK1106615T3 (da) Substituerede 1,4-dihydropyridinforbindelser som bradykininantagonister
DK0952157T3 (da) 9a, 11b-dehydroderivater af 9-oxim-3-keto-6-0-methylerythromycin
TH58670B (th) อนุพันธ์ 2-อะมิโน-3-(แอลคิล)-พิริมิโดน
TH65449A (th) สารยับยั้ง hiv อินทีเกรส
IT1274040B (it) Composizioni farmaceutiche per la prevenzione e/o il trattamento di disturbi gastrointestinali inclusa l'ulcera

Legal Events

Date Code Title Description
8380 Miscellaneous part iii

Free format text: DER VERTRETER IST ZU AENDERN IN: LEDERER & KELLER, 80538 MUENCHEN

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee