DE59912399D1 - Durchfluss-scheranalysator für biologisch aktive moleküle in flüssigkeitsschichten auf oberflächen, verfahren zur analyse einer flüssigkeit und verfahren zur bestimmung der dicke einer ultradünnen flüssigkeitsschicht - Google Patents

Durchfluss-scheranalysator für biologisch aktive moleküle in flüssigkeitsschichten auf oberflächen, verfahren zur analyse einer flüssigkeit und verfahren zur bestimmung der dicke einer ultradünnen flüssigkeitsschicht

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Publication number
DE59912399D1
DE59912399D1 DE59912399T DE59912399T DE59912399D1 DE 59912399 D1 DE59912399 D1 DE 59912399D1 DE 59912399 T DE59912399 T DE 59912399T DE 59912399 T DE59912399 T DE 59912399T DE 59912399 D1 DE59912399 D1 DE 59912399D1
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Germany
Prior art keywords
liquid
thickness
flow
ultra
analyzer
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Expired - Lifetime
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DE59912399T
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German (de)
English (en)
Inventor
Peter Jennissen
Thomas Zumbrink
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/648Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/405Concentrating samples by adsorption or absorption
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/11Automated chemical analysis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/11Automated chemical analysis
    • Y10T436/117497Automated chemical analysis with a continuously flowing sample or carrier stream
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/11Automated chemical analysis
    • Y10T436/117497Automated chemical analysis with a continuously flowing sample or carrier stream
    • Y10T436/118339Automated chemical analysis with a continuously flowing sample or carrier stream with formation of a segmented stream

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Length Measuring Devices By Optical Means (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE59912399T 1998-05-25 1999-05-25 Durchfluss-scheranalysator für biologisch aktive moleküle in flüssigkeitsschichten auf oberflächen, verfahren zur analyse einer flüssigkeit und verfahren zur bestimmung der dicke einer ultradünnen flüssigkeitsschicht Expired - Lifetime DE59912399D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19823301 1998-05-25
PCT/DE1999/001529 WO1999061896A1 (de) 1998-05-25 1999-05-25 Durchfluss-scheranalysator für biologisch aktive moleküle in flüssigkeitsschichten auf oberflächen

Publications (1)

Publication Number Publication Date
DE59912399D1 true DE59912399D1 (de) 2005-09-15

Family

ID=7868841

Family Applications (2)

Application Number Title Priority Date Filing Date
DE59912399T Expired - Lifetime DE59912399D1 (de) 1998-05-25 1999-05-25 Durchfluss-scheranalysator für biologisch aktive moleküle in flüssigkeitsschichten auf oberflächen, verfahren zur analyse einer flüssigkeit und verfahren zur bestimmung der dicke einer ultradünnen flüssigkeitsschicht
DE19980961T Expired - Lifetime DE19980961D2 (de) 1998-05-25 1999-05-25 Durchfluss-Scheranalysator für biologisch aktive Moleküle in Flüssigkeitsschichten auf Oberflächen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19980961T Expired - Lifetime DE19980961D2 (de) 1998-05-25 1999-05-25 Durchfluss-Scheranalysator für biologisch aktive Moleküle in Flüssigkeitsschichten auf Oberflächen

Country Status (9)

Country Link
US (1) US6843963B1 (https=)
EP (1) EP1082601B1 (https=)
JP (1) JP3935317B2 (https=)
AT (1) ATE301831T1 (https=)
AU (1) AU760704B2 (https=)
CA (1) CA2333391C (https=)
DE (2) DE59912399D1 (https=)
ES (1) ES2247820T3 (https=)
WO (1) WO1999061896A1 (https=)

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ATE337094T1 (de) * 2001-04-26 2006-09-15 Univ Bruxelles Verfahren zur beschleunigung und verstärkung der bindung von zielkomponenten an rezeptoren und vorrichtung dafür
DE10258048A1 (de) 2002-12-11 2004-06-24 Man Roland Druckmaschinen Ag Gummituchzylinder für Offset-Druckmaschinen
US7417737B2 (en) * 2003-12-02 2008-08-26 Fujilfilm Corporation Method for measuring surface plasmon resonance
EP1795886A4 (en) 2004-08-24 2010-04-07 Fujifilm Corp METHOD FOR CALCULATING THE DISSOCIATION CONSTANT IN SURFACE PLASMON RESONANCE ANALYSIS
US7449343B2 (en) 2004-09-07 2008-11-11 Fujifilm Corporation Method for measuring surface plasmon resonance
US20070202609A1 (en) * 2004-11-09 2007-08-30 Roper D K Apparatus and methods for increasing lateral mass transfer over molecule sensors
WO2007024800A2 (en) * 2005-08-22 2007-03-01 Applera Corporation Device and method for making discrete volumes of a first fluid in contact with a second fluid, which are immiscible with each other
DE102007012866A1 (de) 2007-03-09 2008-09-18 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Flusskanalsystem und Verfahren zum Anbinden von Analyten an Liganden
JP5033820B2 (ja) * 2009-02-03 2012-09-26 株式会社日立ハイテクノロジーズ 全反射顕微鏡装置、及び蛍光試料分析方法
DE102010041426A1 (de) * 2010-09-27 2012-05-03 Siemens Aktiengesellschaft Messeinheit und Verfahren zur optischen Untersuchung einer Flüssigkeit zur Bestimmung einer Analyt-Konzentration
DE102012102983A1 (de) 2012-04-05 2013-10-10 Carl Zeiss Microscopy Gmbh Verfahren und Vorrichtung zum Bestimmen eines kritischen Winkels eines Anregungslichtstrahls
EP2677037B1 (en) * 2012-06-21 2016-04-13 Synapse B.V. Simultaneous measurement of thrombin generation and clot strength in plasma and whole blood
WO2018021238A1 (ja) * 2016-07-28 2018-02-01 コニカミノルタ株式会社 検出チップ、検出システムおよび検出方法
ES2947300T3 (es) * 2017-02-15 2023-08-04 Otsuka Pharma Co Ltd Chip de inspección y sistema de inspección
DE102017115661A1 (de) 2017-07-12 2019-01-17 Endress+Hauser Conducta Gmbh+Co. Kg Optischer Sensor
CN109580482A (zh) * 2018-12-04 2019-04-05 华北电力大学 一种纳米颗粒强化气液传质过程中微观状态观测装置及其方法
JP7482887B2 (ja) * 2019-09-24 2024-05-14 大塚製薬株式会社 検出方法および検出装置

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4028056A (en) * 1976-04-20 1977-06-07 Technicon Instruments Corporation Substance separation technique
US4413505A (en) * 1981-03-09 1983-11-08 Environmental Sciences Associates, Inc. Electrochemical flow cell, particularly use with liquid chromatography
DE3168903D1 (en) * 1980-08-28 1985-03-28 Du Pont Flow analysis
AU557816B2 (en) * 1981-09-18 1987-01-08 Prutec Ltd. Method for the determination of species in solution with an optical wave-guide
US4978503A (en) * 1984-06-13 1990-12-18 Ares-Serono Research & Development Limited Partnership Devices for use in chemical test procedures
GB8829942D0 (en) * 1988-12-22 1989-02-15 Isis Innovations Ltd Method
RU2095787C1 (ru) * 1994-09-27 1997-11-10 Московский областной научно-исследовательский клинический институт Оптическая кювета для исследования жидкости в тонком слое
US5716852A (en) * 1996-03-29 1998-02-10 University Of Washington Microfabricated diffusion-based chemical sensor
US6184978B1 (en) * 1996-05-15 2001-02-06 International Remote Imaging Systems, Inc. Method and apparatus for verifying uniform flow of a fluid sample through a flow cell and distribution on a slide

Also Published As

Publication number Publication date
JP2002516993A (ja) 2002-06-11
US6843963B1 (en) 2005-01-18
JP3935317B2 (ja) 2007-06-20
ATE301831T1 (de) 2005-08-15
ES2247820T3 (es) 2006-03-01
AU760704B2 (en) 2003-05-22
EP1082601B1 (de) 2005-08-10
CA2333391C (en) 2012-01-31
CA2333391A1 (en) 1999-12-02
AU5149499A (en) 1999-12-13
WO1999061896A1 (de) 1999-12-02
DE19980961D2 (de) 2002-01-03
EP1082601A1 (de) 2001-03-14

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