DE58902111D1 - Thioverbindungen. - Google Patents
Thioverbindungen.Info
- Publication number
- DE58902111D1 DE58902111D1 DE8989810170T DE58902111T DE58902111D1 DE 58902111 D1 DE58902111 D1 DE 58902111D1 DE 8989810170 T DE8989810170 T DE 8989810170T DE 58902111 T DE58902111 T DE 58902111T DE 58902111 D1 DE58902111 D1 DE 58902111D1
- Authority
- DE
- Germany
- Prior art keywords
- lower alkyl
- halo
- unsubstituted
- nitro
- mono
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- SCVJRXQHFJXZFZ-KVQBGUIXSA-N 2-amino-9-[(2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3h-purine-6-thione Chemical compound C1=2NC(N)=NC(=S)C=2N=CN1[C@H]1C[C@H](O)[C@@H](CO)O1 SCVJRXQHFJXZFZ-KVQBGUIXSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000004802 benzothiophens Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Saccharide Compounds (AREA)
- Mechanical Coupling Of Light Guides (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH99888 | 1988-03-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE58902111D1 true DE58902111D1 (de) | 1992-10-01 |
Family
ID=4200067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8989810170T Expired - Lifetime DE58902111D1 (de) | 1988-03-16 | 1989-03-07 | Thioverbindungen. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US5051421A (show.php) |
| EP (1) | EP0336886B1 (show.php) |
| JP (1) | JPH01308276A (show.php) |
| AT (1) | ATE79876T1 (show.php) |
| DE (1) | DE58902111D1 (show.php) |
| DK (1) | DK126989A (show.php) |
| ES (1) | ES2052059T3 (show.php) |
| GR (1) | GR3005857T3 (show.php) |
| IE (1) | IE890828L (show.php) |
| PT (1) | PT90002B (show.php) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5436246A (en) * | 1992-09-17 | 1995-07-25 | Merrell Dow Pharmaceuticals Inc. | Serotonin receptor agents |
| DE69525763T2 (de) * | 1994-04-11 | 2002-10-02 | Chugai Seiyaku K.K., Tokio/Tokyo | 4,6-DI-t-BUTYL-2,3-DIHYDROBENZOTHIOPHENE, DIE LDL OXIDATION HEMMEN |
| FR2793245B1 (fr) * | 1999-05-05 | 2002-10-11 | Adir | Nouveaux composes pyridiniques ou piperidiniques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE339235B (show.php) * | 1965-06-01 | 1971-10-04 | Haessle Ab | |
| US4514415A (en) * | 1981-10-28 | 1985-04-30 | Ciba Geigy Corporation | Benzofuran-2(3H)-ones used as anti-inflammatory agents |
| US4663344A (en) * | 1985-03-11 | 1987-05-05 | Merck & Co., Inc. | Anti-inflammatory and analgesic 3-hydroxybenzo[b]thiophene derivatives, compositions, and method of use therefor |
-
1989
- 1989-03-07 DE DE8989810170T patent/DE58902111D1/de not_active Expired - Lifetime
- 1989-03-07 ES ES89810170T patent/ES2052059T3/es not_active Expired - Lifetime
- 1989-03-07 EP EP89810170A patent/EP0336886B1/de not_active Expired - Lifetime
- 1989-03-07 AT AT89810170T patent/ATE79876T1/de not_active IP Right Cessation
- 1989-03-14 PT PT90002A patent/PT90002B/pt not_active IP Right Cessation
- 1989-03-15 DK DK126989A patent/DK126989A/da not_active Application Discontinuation
- 1989-03-15 IE IE890828A patent/IE890828L/xx unknown
- 1989-03-16 JP JP1062328A patent/JPH01308276A/ja active Pending
-
1990
- 1990-01-18 US US07/467,088 patent/US5051421A/en not_active Expired - Fee Related
-
1991
- 1991-06-27 US US07/722,080 patent/US5147889A/en not_active Expired - Fee Related
-
1992
- 1992-10-01 GR GR920401776T patent/GR3005857T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0336886B1 (de) | 1992-08-26 |
| EP0336886A1 (de) | 1989-10-11 |
| ATE79876T1 (de) | 1992-09-15 |
| PT90002B (pt) | 1994-06-30 |
| DK126989A (da) | 1989-09-17 |
| PT90002A (pt) | 1989-11-10 |
| US5147889A (en) | 1992-09-15 |
| US5051421A (en) | 1991-09-24 |
| DK126989D0 (da) | 1989-03-15 |
| ES2052059T3 (es) | 1994-07-01 |
| IE890828L (en) | 1989-09-16 |
| GR3005857T3 (show.php) | 1993-06-07 |
| JPH01308276A (ja) | 1989-12-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |