DE499078C - Process for converting salt brines into a therapeutically effective paste or cream form - Google Patents

Process for converting salt brines into a therapeutically effective paste or cream form

Info

Publication number
DE499078C
DE499078C DEB120822D DEB0120822D DE499078C DE 499078 C DE499078 C DE 499078C DE B120822 D DEB120822 D DE B120822D DE B0120822 D DEB0120822 D DE B0120822D DE 499078 C DE499078 C DE 499078C
Authority
DE
Germany
Prior art keywords
therapeutically effective
cream
cream form
salt brines
effective paste
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DEB120822D
Other languages
German (de)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PHARMAPORT GES fur CHEMISCH P
Original Assignee
PHARMAPORT GES fur CHEMISCH P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PHARMAPORT GES fur CHEMISCH P filed Critical PHARMAPORT GES fur CHEMISCH P
Priority to DEB120822D priority Critical patent/DE499078C/en
Application granted granted Critical
Publication of DE499078C publication Critical patent/DE499078C/en
Expired legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

Verfahren zur Überführung von Salzsolen in eine therapeutisch wirksame Pasten- oder Kremform Die Erfindung betrifft ein Verfahren zur Leberführung von Salzsolen in eine therapeutisch wirksame Pasten- oder Kremform.Process for converting brine into a therapeutically effective one Paste or cream form The invention relates to a method for liver guidance of Salt brines in a therapeutically effective paste or cream form.

Es ist bekannt, daß man durch teilweise Versei.fung von Fetten bei Gegemvart von Glycerin haltbare Emulsionen darstellen kann, die heute z. B. als Toilettekrem allgemeine Anwendung finden. Wenn man beispielsweise io Teile Stearinsäüre zu 1/3 verseift und mit 2o Teilen Glycerin vermischt, kann man dieser Mischung zur Erzeugung eines Kretnes ca.7o Teile Wasser einverleiben, ohne Abtrennung von Wasser befürchten zu müssen. Desgleichen erhält man haltbare Emulsionen unter Verwendung von. 20 v. H. Glycerin, wenn man die Stearinsäure in ihr Ammoniumsalz verwandelt.It is known that by partial saponification of fats Gegemvart of glycerine can represent durable emulsions that today z. B. as Toilet creams find general use. For example, if you have 10 parts stearic acid saponified to 1/3 and mixed with 20 parts glycerine, this mixture can be used To create a crete, incorporate about 70 parts of water without separating off water to fear. Durable emulsions are also obtained using them from. 20 BC H. glycerine, if the stearic acid is converted into its ammonium salt.

Macht man dagegen solche Versuche mit konzentrierten wäßrigen Salzlösungen an Stelle von Wasser, z. B. mit einer 2o°/oigen Kochsalzlösung, so bleibt die Emulsion nicht bestehen. Es scheidet sich Salzlösung ab trotz hohen Gehaltes von etwa 2o v. H. Glycerin.On the other hand, such experiments are carried out with concentrated aqueous salt solutions instead of water, e.g. B. with a 20% saline solution, the emulsion remains not pass. Salt solution separates out in spite of the high content of about 2o v. H. Glycerin.

Nach vorliegender Erfindung werden. haltbare Emulsionen selbst mit sehr konzentrierten Salzlösungen dadurch erzielt, daß die Fette durch Zugabe von Saponin beneizbar gemacht werden. Die Verwendung des Saponins zum Emulgieren verschiedener Stoffe ist an und für sich bbkannt. Desgleichen ist es bekannt, die Benetzungswirkung des Saponins dazu zu benutzen, Streupulver und andere pulverförmige Stoffe, welche sich schwer benetzen lassen, in trockener Form in Fetten zu suspendieren. und auf di,esie, Weise Salben herzustellen (vgl. z. B. Patent 283728). According to the present invention. Durable emulsions are achieved even with very concentrated salt solutions by making the fats accessible by adding saponin. The use of saponin to emulsify various substances is known in and of itself. It is also known to use the wetting effect of saponin to suspend scattering powder and other powdery substances, which are difficult to wet, in dry form in fats. and in di, esie way to make ointments (see e.g. patent 283728).

Die vorliegende Erfindung beruht nun auf der neuen Erkenntnis, .daß Sapon.in auch die Möglichkeit bietet, größere Mengen von Salzen in der Form von konzentrierten Lösungen in Kreme einzuverleiben, und zwar so, daß ein dauernd haltbarer, sich nicht verändernder Krem entsteht. Man kann sogar, wie sich herausgestellt hat, bei Zugabe von Saponin .die Menge des Glycerins bedeutend herabmindern. So gelang es z. B., folgende Kombination zu einem beständigen, sich nicht scheidenden Krem zusammenzureiben: 5.4 g Fett -a- 8;g Kalilauge + 6 -Wasser + io ccm Spiritus -f- o,or - Saponin, auf dem Wasserbade verseift, werden mit einer heißen Lösung von 40 g Kochsalz in 8o g Wasser +o,oi g Saponin + io g Glycerin heiß zusammengerührt und bis zum Erkalten verrieben.The present invention is based on the new knowledge. That Sapon.in also offers the possibility of larger amounts of salts in the form of to incorporate concentrated solutions in cream, in such a way that a long-lasting, unchanging cream arises. One can even, as it turned out, when adding saponin, reduce the amount of glycerin significantly. So succeeded it z. B., the following combination to a permanent, non-separating cream rub together: 5.4 g fat -a- 8; g potassium hydroxide + 6 -water + 10 ccm spirit -f- o, or - saponin, saponified on the water bath, are mixed with a hot solution of 40 g table salt in 80 g water + o, oi g saponin + 10 g glycerin stirred together hot and rubbed in until cold.

Das erwähnte Verreiben der Bestandteile bis zum Erkalten ist für die Erzielung der gewünschten Wirkung von ausschlaggebender Bedeutung.The mentioned rubbing of the ingredients until they cool is for them Achieving the desired effect is crucial.

Der Vorgang spielt sich dabei so ab, daß die in der hochkonzentrierten wäßrigen Salzlösung in gallertartigen Klümpchen liegende Seife nach etwa 5 bis zo Minuten langem Rühren allmählich fester und zäher wird und schließlich bei fortschreitendem Erkalten unter Reiben mit dem Pistill eine kremartige Konsistenz annimmt.The process takes place in such a way that those in the highly concentrated aqueous saline solution lying in gelatinous lumps Soap after Stirring for about 5 to 10 minutes will gradually become firmer and tougher and eventually As it cools down, rub it with a pestle to get a creamy consistency accepts.

In ähnlicher Weise, wie hier die Kochsalzlösung, lassen sich alle möglichen, ihrer chemischen Zusammensetzung nach geeigneten Heilsalze in hoher Konzentration in Kremform bringen. Es ist also durch die Erfindung möglich geworden, Heilsalze in Fo= von Seifenkrem. zu verwenden und .dadurch ,die Heilwirkung des Salzes mit der die Hautdurchblutung anregenden Wirkung des Seifenkrems zu vereinigen.In a similar way to the saline solution here, all of them can be removed possible, their chemical composition according to suitable medicinal salts in high concentration put in cream form. So the invention made it possible to use healing salts in Fo = from soap cream. to use and .this way, the medicinal properties of the salt with to unite the skin blood circulation stimulating effect of the soap cream.

Claims (1)

PATENTANSPRUCH: Verfahren zur Überführung von Salzsolen in eine therapeutisch wirksame Pasten- oder Kremform, dadurch gekennzeichnet, daß hochkonzentrierte, wäßrige Salzlösungen unter Beigabe geringer Mengen Sap-onin mit überfettetem Seifenkrem in heißem Zustande zusammengebracht und bis zum Erkalten ;derMischung verrührt werden.PATENT CLAIM: Process for converting salt brines into a therapeutic one effective paste or cream form, characterized in that highly concentrated, aqueous Salt solutions with the addition of small amounts of sap-onin with over-greased soap cream brought together in a hot state and stirred into the mixture until it cools.
DEB120822D 1925-07-17 1925-07-17 Process for converting salt brines into a therapeutically effective paste or cream form Expired DE499078C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DEB120822D DE499078C (en) 1925-07-17 1925-07-17 Process for converting salt brines into a therapeutically effective paste or cream form

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEB120822D DE499078C (en) 1925-07-17 1925-07-17 Process for converting salt brines into a therapeutically effective paste or cream form

Publications (1)

Publication Number Publication Date
DE499078C true DE499078C (en) 1930-05-31

Family

ID=6995377

Family Applications (1)

Application Number Title Priority Date Filing Date
DEB120822D Expired DE499078C (en) 1925-07-17 1925-07-17 Process for converting salt brines into a therapeutically effective paste or cream form

Country Status (1)

Country Link
DE (1) DE499078C (en)

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