DE305722C - - Google Patents
Info
- Publication number
- DE305722C DE305722C DENDAT305722D DE305722DA DE305722C DE 305722 C DE305722 C DE 305722C DE NDAT305722 D DENDAT305722 D DE NDAT305722D DE 305722D A DE305722D A DE 305722DA DE 305722 C DE305722 C DE 305722C
- Authority
- DE
- Germany
- Prior art keywords
- thymol
- water
- menthol
- oil
- coumarin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- ZYGHJZDHTFUPRJ-UHFFFAOYSA-N Coumarin Chemical compound C1=CC=C2OC(=O)C=CC2=C1 ZYGHJZDHTFUPRJ-UHFFFAOYSA-N 0.000 claims description 14
- MGSRCZKZVOBKFT-UHFFFAOYSA-N Thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 claims description 10
- 239000005844 Thymol Substances 0.000 claims description 10
- 229960000790 thymol Drugs 0.000 claims description 10
- 229930007823 thymol Natural products 0.000 claims description 10
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims description 8
- 229960004873 LEVOMENTHOL Drugs 0.000 claims description 8
- 229940041616 Menthol Drugs 0.000 claims description 8
- 229960000956 coumarin Drugs 0.000 claims description 7
- 235000001671 coumarin Nutrition 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 229940051866 Mouthwash Drugs 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 239000002324 mouth wash Substances 0.000 claims description 3
- 239000000243 solution Substances 0.000 claims description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 239000000126 substance Substances 0.000 claims 1
- 239000003921 oil Substances 0.000 description 8
- UIIMBOGNXHQVGW-UHFFFAOYSA-M NaHCO3 Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 4
- 230000000249 desinfective Effects 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 125000003118 aryl group Chemical group 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 2
- 235000017557 sodium bicarbonate Nutrition 0.000 description 2
- 239000000341 volatile oil Substances 0.000 description 2
- -1 B. 20 g each Chemical compound 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N Carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-UUNJERMWSA-N Lactose Natural products O([C@@H]1[C@H](O)[C@H](O)[C@H](O)O[C@@H]1CO)[C@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@H](CO)O1 GUBGYTABKSRVRQ-UUNJERMWSA-N 0.000 description 1
- 235000016257 Mentha pulegium Nutrition 0.000 description 1
- 240000006217 Mentha pulegium Species 0.000 description 1
- FEWJPZIEWOKRBE-XIXRPRMCSA-N Mesotartaric acid Chemical compound OC(=O)[C@@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-XIXRPRMCSA-N 0.000 description 1
- ZQBAKBUEJOMQEX-UHFFFAOYSA-N Phenyl salicylate Chemical compound OC1=CC=CC=C1C(=O)OC1=CC=CC=C1 ZQBAKBUEJOMQEX-UHFFFAOYSA-N 0.000 description 1
- NTHWMYGWWRZVTN-UHFFFAOYSA-N Sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000001476 alcoholic Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 235000014510 cooky Nutrition 0.000 description 1
- 239000002781 deodorant agent Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 235000001050 hortel pimenta Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000004570 mortar (masonry) Substances 0.000 description 1
- 235000006678 peppermint Nutrition 0.000 description 1
- 235000015132 peppermint Nutrition 0.000 description 1
- 235000007735 peppermint Nutrition 0.000 description 1
- PNIJRIIGBGFYHF-UHFFFAOYSA-N perborate(2-) Chemical compound O[B-]1(O)OO[B-](O)(O)OO1 PNIJRIIGBGFYHF-UHFFFAOYSA-N 0.000 description 1
- 229960000969 phenyl salicylate Drugs 0.000 description 1
- 235000019353 potassium silicate Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- MWNQXXOSWHCCOZ-UHFFFAOYSA-L sodium;oxido carbonate Chemical compound [Na+].[O-]OC([O-])=O MWNQXXOSWHCCOZ-UHFFFAOYSA-L 0.000 description 1
- 229960001367 tartaric acid Drugs 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Description
KAISERLICHES'IMPERIAL '
PATENTAMT.PATENT OFFICE.
Es ist bekannt, daß Thymol ein vorzügliches und sehr wirksames Munddesinfiziens ist. Es ist jedoch so schwer dosierbar, daß sein Gebrauch für den angeführten Zweck höchst unbequem erscheint. Auch der Geschmack reinen Thymols ohne Geschmackskorrigentien wirkt zu scharf. In alkoholischer Lösung läßt Thymol sich dagegen bequem dosieren und auch mit aromatischen Prinzipien,It is known that thymol is an excellent and very effective oral disinfectant is. However, it is so difficult to dose that its use for the stated purpose seems extremely uncomfortable. Also the taste of pure thymol without taste corrections looks too sharp. On the other hand, thymol can be used comfortably in an alcoholic solution dose and also with aromatic principles,
ίο. wie Menthol und Cumarin kombinieren. Alle diese drei Körper geben, ohne direkt löslich zu sein, doch so viel von ihren Eigenschaften an. Wasser ab, daß sie demselben ihren vorzüglichen desinfizierenden und aromatischenίο. how to combine menthol and coumarin. All these three bodies give, without being directly soluble, yet so much of their properties at. Water off, that they will give them their excellent ones disinfectant and aromatic
Charakter mitteilen.. "Share character .. "
Es ist nun eine bekannte Beobachtung (s.It is now a well-known observation (see p.
Schmidt, pharmaceutische Chemie, 5 Aufl.Schmidt, pharmaceutische Chemie, 5 ed.
Bd. IL, S. 1097), daß Thymol mit Menthol und Cumarin zusammengemischt nicht pulverisier-Vol. IL, p. 1097) that thymol with menthol and Coumarin mixed together not pulverized
bar ist, sondern zu einem öl zerfließt. Hierauf gründet sich das nachfolgende Verfahren. ■·.■-■-.is bar, but melts into an oil. On that the following procedure is based. ■ ·. ■ - ■ -.
Da das erwähnte Öl in Wasser nicht lös-, lieh ist und für sich in solch kleinen Mengen nicht dosierbar wäre, muß man es, wie es bei anderen Reagentien und Ölen, auch bekannt ist, mit wasserlöslichen Körpern fein verrühren. Man kann auf diese Weise eine beliebige Verdünnung erhalten, und Thymol und Menthol.Since the mentioned oil does not dissolve in water, is borrowed and could not be dosed in such small amounts, one has to do it, as is the case with Mix other reagents and oils, also known, finely with water-soluble solids. Any dilution can be obtained in this way, and thymol and menthol.
derart in Waäser verteilen, daß es praktisch eine Lösung darstellt.Distribute in water in such a way that it is practical represents a solution.
Die Anwehdung ätherischer öle in Vermengung mit trockenen löslichen Pulvern ist an sich in der Praxis bekannt. . Zu den Produkten dieser Anwendung gehören z. B. die : bekannten Pfefferminzplätzchen, ferner gibtThe application of essential oils in blending with dry soluble powders is known per se in practice. . To the Products of this application include: B. the: well-known peppermint cookies, there are also
Gehes Codex ein Rezept an (Sick), wonach man Soda, Weinsäure und_nicht näher bezeichnete ätherische öle zur Herstellung eines trockenen löslichen Munddesinfiziens vermischt. Der Fortschritt vorliegenden neuen Verfahrens liegt aber in der Ersetzung indifferenter ätherischer öle durch mehrere an sich feste Körper, die gleichzeitig desodorierend, erfrischend und desinfizierend wirken.Go to Codex for a recipe (Sick), according to which soda, tartaric acid and_not specified essential oils mixed to make a dry soluble mouth sanitizer. The advance of the present new procedure lies in the replacement of more indifferent, ethereal ones oils through several solid bodies that are deodorant, refreshing and at the same time have a disinfectant effect.
Das Verfahren beruht darauf, daß man die an sich bekannte Tatsache, daß Thymol. Menthol und Cumarin sich verflüssigen, benutzt, sowie ferner in Kombination damit die ebenfalls bekannte Tatsache, daß man öle mit wasserlöslichen Körpern mischt. Durch die Kombination dieser beiden bekannten Maßnahmen wird das an und für sich unlösliche Öl in einen praktisch wasserlöslichen Zustand gebracht. So erzielt man einen neuen technischen Effekt in der Möglichkeit, Thymol, Menthol, Cumarin gemeinsam zu einem Mundwasser zu vereinigen, zu dessen Herstellung kein Alkohol mehr nötig ist. Als aufsaugende Körper eignen sich z. B. Milchzucker, Natriumbicarbonat, Percarbonat, Perborat, Natriumphosphat oder derartige Gemenge, die man nach bestimmten Verhältnissen mischt und nach bestimmten Mengen ins Wasser bringt.The method is based on the fact that one known per se that thymol. menthol and coumarin liquefy, used, and also in combination therewith the also known The fact that oils are mixed with water-soluble solids. By combining of these two known measures, the oil, which is in and of itself insoluble, becomes practical in one brought water-soluble state. This is how a new technical effect is achieved in the possibility of To combine thymol, menthol, coumarin together to a mouthwash, for the production of which no alcohol is necessary. as absorbent bodies are suitable for. B. lactose, sodium bicarbonate, percarbonate, perborate, Sodium phosphate or such a mixture, which one according to certain proportions mixes and brings it into the water according to certain quantities.
Gleiche Teile Thymol, Menthol, Cumarin, z. B. je 20 g, werden in einer Reibschale zusammengebracht. Sehr bald hat sich ein dickes öl gebildet; dieses Öl wird mit 1500 g Natriumbicarbonat verrieben und die erhaltene Masse in Mengen von etwa 0,3 bis 0,4 g auf einEqual parts of thymol, menthol, coumarin, e.g. B. 20 g each, are brought together in a mortar. Very soon a thick oil has formed; this oil is made with 1500 g of sodium bicarbonate rubbed and the mass obtained in amounts of about 0.3 to 0.4 g on a
Wasserglas, je1 nach Geschmack, zur Herstellung des Mundwassers verwandt.Water glass, 1 each according to taste, used to make the mouthwash.
Etwaige/andere Zusätze, wie Salol o. dgl., oder andere Aromatika kann man natürlich ohne weiteres mit zur Anwendung bringen.Any / other additives, such as Salol or the like, or other aromatics can of course be used without further ado.
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE305722C true DE305722C (en) |
Family
ID=559197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DENDAT305722D Active DE305722C (en) |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE305722C (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2554464A (en) * | 1944-02-28 | 1951-05-22 | Kraus Alfred | Oral composition |
| DE3528709A1 (en) * | 1985-08-09 | 1987-02-19 | Schleicher Peter | ORAL CARE PRODUCTS |
| EP0338978A2 (en) * | 1988-03-31 | 1989-10-25 | Warner-Lambert Company | Taste masking of thymol |
-
0
- DE DENDAT305722D patent/DE305722C/de active Active
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2554464A (en) * | 1944-02-28 | 1951-05-22 | Kraus Alfred | Oral composition |
| DE3528709A1 (en) * | 1985-08-09 | 1987-02-19 | Schleicher Peter | ORAL CARE PRODUCTS |
| EP0217041A1 (en) * | 1985-08-09 | 1987-04-08 | Schleicher, Peter, Dr. med. | Dentifrice |
| EP0338978A2 (en) * | 1988-03-31 | 1989-10-25 | Warner-Lambert Company | Taste masking of thymol |
| EP0338978A3 (en) * | 1988-03-31 | 1990-03-28 | Warner-Lambert Company | Taste masking of thymol |
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