DE490416C - Process for the preparation of diiodine substitution products of 2-oxypyridine and its derivatives - Google Patents
Process for the preparation of diiodine substitution products of 2-oxypyridine and its derivativesInfo
- Publication number
- DE490416C DE490416C DEC39597D DEC0039597D DE490416C DE 490416 C DE490416 C DE 490416C DE C39597 D DEC39597 D DE C39597D DE C0039597 D DEC0039597 D DE C0039597D DE 490416 C DE490416 C DE 490416C
- Authority
- DE
- Germany
- Prior art keywords
- oxypyridine
- diiodine
- derivatives
- preparation
- substitution products
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pyridine Compounds (AREA)
Description
Verfahren zur Darstellung von Dijodsubstitutionsprodukten des 2-Oxypyridins und seiner Derivate Die Jodierung des 2 - Oxypyridins geht äußerst schwer vonstatten. Beim Behandeln von 2-Oxypyridin mit Jod in Gegenwart von 3 oprozentiger Wasserstoffsup eroxydlösung und etwas Eisen bei erhöhter Temperatur erhält man nur geringe Mengen des 5-Jod-z-Oxypyridins (vgl. Berichte 58 [1925], S. 116).Process for the preparation of diiodine substitution products of 2-oxypyridine and its derivatives The iodination of 2 - oxypyridine is extremely difficult. When treating 2-oxypyridine with iodine in the presence of 3% hydrogen sup Oxide solution and a little iron at elevated temperature are only obtained in small quantities of 5-iodine-z-oxypyridine (cf. reports 58 [1925], p. 116).
Es wurde nun gefunden, daß man mit Hilfe von Chlorjod das 2-Oxypyridin oder dessen Dürivatie in mineralsaurer Lösung leicht in Dijodsubstitutionsprodukte überführen kann.It has now been found that 2-oxypyridine can be obtained with the aid of chlorine iodine or its Dürivatie in mineral acid solution easily into diiodine substitution products can convict.
Beispiel i Zog 2-Oxypyridin werden in 25 ccm verdünnter Salzsäure gelöst und mit 35 g Jodmonochlorid in verdünnter Salzsäure versetzt. Nach mehrstündigem Stehen bei: gewöhnlicher Temperatur scheidet sich das 2-Oxy-3, 5-dijodpyridin in reiner Form ab.Example i 2-Oxypyridine is dissolved in 25 cc of dilute hydrochloric acid dissolved and mixed with 35 g of iodine monochloride in dilute hydrochloric acid. After several hours Standing at: ordinary temperature, the 2-oxy-3, 5-diiodopyridine separates into pure form.
Das z-Oxy-3, 5-dijodpyridin läßt sich aus einem Alkohol-Pyridin-Gemis.ch oder aus Eisessig umkristallisieren. Es schmilzt bei a55°, bei z65° zersetzt ,es sich. In heißer Natronlauge ist es löslich, beim Erkalten kristallisiert die Natriumverbindung aus.The z-Oxy-3, 5-diiodopyridine can be obtained from an alcohol-pyridine-Gemis.ch or recrystallize from glacial acetic acid. It melts at a55 °, decomposes at z65 °, it themselves. It is soluble in hot sodium hydroxide solution; when it cools, the sodium compound crystallizes the end.
Beispiel 2 i o g 2 - Oxy - 6 - methylpyridin werden in 5o.ccm verdünnter Salzsäure mit 309 jo(dmonochlorid in 6o ccm verdünnter Salzsäure vermischt und bei Zimmertemperatur in verschlossener Flasche sich selbst überlassen. Nach ,18 Stunden hat sich das 2 - Oxy-3, 5-dijod-6-methylpyridin als graues Pulver am Boden der Flasche abgesetzt. Man saugt ab, löst in Natronlauge und fällt mit schwefliger Säure. Das rein weiße z-Oxy-3, 5-dijod-6-methylpyridin kann dann noch aus Alkohol umkristallisiert werden. Es schmilzt bei 23o° unter Zersetzung.Example 2 Two-oxy-6-methylpyridine are mixed in 50% of dilute hydrochloric acid with 309 % of monochloride in 60 cc of dilute hydrochloric acid and left to stand in a sealed bottle at room temperature. After 18 hours, the 2-oxy-3 5-diiodo-6-methylpyridine deposited as a gray powder at the bottom of the bottle. It is suctioned off, dissolved in sodium hydroxide solution and precipitated with sulphurous acid. The pure white z-oxy-3, 5-diiodo-6-methylpyridine can then still precipitate Recrystallized alcohol, which melts at 230 ° with decomposition.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEC39597D DE490416C (en) | 1927-04-01 | 1927-04-01 | Process for the preparation of diiodine substitution products of 2-oxypyridine and its derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEC39597D DE490416C (en) | 1927-04-01 | 1927-04-01 | Process for the preparation of diiodine substitution products of 2-oxypyridine and its derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE490416C true DE490416C (en) | 1930-01-27 |
Family
ID=7023804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DEC39597D Expired DE490416C (en) | 1927-04-01 | 1927-04-01 | Process for the preparation of diiodine substitution products of 2-oxypyridine and its derivatives |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE490416C (en) |
-
1927
- 1927-04-01 DE DEC39597D patent/DE490416C/en not_active Expired
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