DE410937C - Process for the preparation of a measles protection serum - Google Patents
Process for the preparation of a measles protection serumInfo
- Publication number
- DE410937C DE410937C DED41608D DED0041608D DE410937C DE 410937 C DE410937 C DE 410937C DE D41608 D DED41608 D DE D41608D DE D0041608 D DED0041608 D DE D0041608D DE 410937 C DE410937 C DE 410937C
- Authority
- DE
- Germany
- Prior art keywords
- measles
- serum
- preparation
- protection
- protection serum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title claims description 6
- 210000002966 serum Anatomy 0.000 title claims description 6
- 201000005505 Measles Diseases 0.000 title claims description 4
- 241001465754 Metazoa Species 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 210000004369 blood Anatomy 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 229960005486 vaccine Drugs 0.000 description 3
- 239000012530 fluid Substances 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 206010013023 diphtheria Diseases 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229940041323 measles vaccine Drugs 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
Description
Verfahren zur Herstellung eines lV(asernschutzserums. Das Hauptpatent betrifft ein Verfahren zur Herstellung eines Masemschutzimpfstoffes aus bakteriendicht filtriertem Nasen-, Rachensekret oder Blut Masernkranker, wobei das Filtrat auf einen Nährboden verimpft und im Brutschrank zum Wachsen gebracht wird.Process for the production of an IV (asern protection serum. The main patent relates to a method for producing a measles protection vaccine from bacteria-tight filtered nasal secretions, throat secretions or blood from measles sufferers, with the filtrate on a nutrient medium is inoculated and made to grow in the incubator.
Zur Durchführung des Verfahrens wird dort ein Nährboden vorgeschlagen, der sich dadurch kennzeichnet, daß man vorteilhaft unveränderte Blutflüssigkeit, die zweckmäßig frei von Formbestandteilen ist, mit einer Flüssigkeit verdünnt, welche die gleichen Ionen im gleichen Verhältnis enthält wie die Blutflüssigkeit und imstande ist, diese Verhältnisse auch während des Keimwachstums aufrechtzuerhalten.To carry out the process, a nutrient medium is proposed there, which is characterized by the fact that one advantageously uses unchanged blood fluid, which is expediently free of mold components, diluted with a liquid which contains the same ions in the same proportion as the blood fluid and capable of is to maintain these conditions also during the germ growth.
Mit diesem Impfstoff werden gesunde, noch urigemaserte Kinder geimpft, wodurch sie nach einiger Zeit eine Immunität gegen virulente, vollgiftige Erreger erwerben.This vaccine is used to vaccinate healthy, still grainy children, which after some time gives them immunity to virulent, fully toxic pathogens acquire.
Der im Hauptpatent vorgeschlagene Weg kann nun erfindungsgemäß auch zur Herstellung eines Masernschutzimpfstoffes angewendet werden, dem das Prinzip der Behringschen Diphterieprophylaxe zugrunde liegt, nämlich mit spezifischen. Erregergiften Tiere vorzubehandeln und durch das Serum solcher vorbehandelten Tiere Schutzstoffe auf gefährdete oder schon infizierte, noch in der Inkubation befindliche Menschen zu übertragen. Damit werden die ersteren vor Infektion geschützt, während bei den letzteren die schon stattgehabte Infektion sich nicht zur Krankheit weiterentwickeln kann.The way proposed in the main patent can now also be used according to the invention to produce a measles vaccine based on the principle Behring's diphtheria prophylaxis is based, namely with specific. Pathogen toxins To pretreat animals and protective substances through the serum of such pretreated animals to people who are at risk or who are already infected and who are still being incubated transferred to. This protects the former from infection, while the in the latter, the infection that has already taken place does not develop into disease can.
Mit dem nach dem Verfahren des Hauptpatentes hergestellten Impfstoff werden in diesem Falle also zunächst gesunde Tiere geimpft, worauf nach gewisser Zeit aus diesen das Serum in bekannter Weise gewonnen wird.With the vaccine produced according to the process of the main patent In this case, healthy animals are first vaccinated, after which a certain Time from these the serum is obtained in a known manner.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DED41608D DE410937C (en) | 1922-04-22 | 1922-04-22 | Process for the preparation of a measles protection serum |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DED41608D DE410937C (en) | 1922-04-22 | 1922-04-22 | Process for the preparation of a measles protection serum |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE410937C true DE410937C (en) | 1925-03-20 |
Family
ID=7046220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DED41608D Expired DE410937C (en) | 1922-04-22 | 1922-04-22 | Process for the preparation of a measles protection serum |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE410937C (en) |
-
1922
- 1922-04-22 DE DED41608D patent/DE410937C/en not_active Expired
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