DE3888872D1 - Verfahren zur Herstellung von Kuprat-Komplexen höherer Ordnung. - Google Patents

Verfahren zur Herstellung von Kuprat-Komplexen höherer Ordnung.

Info

Publication number
DE3888872D1
DE3888872D1 DE88109047T DE3888872T DE3888872D1 DE 3888872 D1 DE3888872 D1 DE 3888872D1 DE 88109047 T DE88109047 T DE 88109047T DE 3888872 T DE3888872 T DE 3888872T DE 3888872 D1 DE3888872 D1 DE 3888872D1
Authority
DE
Germany
Prior art keywords
higher order
complex
cuprate
preparation
order cuprate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE88109047T
Other languages
English (en)
Other versions
DE3888872T2 (de
Inventor
Arthur Lee Campbell
James Richard Behling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of DE3888872D1 publication Critical patent/DE3888872D1/de
Application granted granted Critical
Publication of DE3888872T2 publication Critical patent/DE3888872T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/08—Copper compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/22—Tin compounds
    • C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE3888872T 1987-06-09 1988-06-07 Verfahren zur Herstellung von Kuprat-Komplexen höherer Ordnung. Expired - Fee Related DE3888872T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/059,695 US4777275A (en) 1987-06-09 1987-06-09 Process of preparing higher order cuprate complexes

Publications (2)

Publication Number Publication Date
DE3888872D1 true DE3888872D1 (de) 1994-05-11
DE3888872T2 DE3888872T2 (de) 1994-08-11

Family

ID=22024644

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3888872T Expired - Fee Related DE3888872T2 (de) 1987-06-09 1988-06-07 Verfahren zur Herstellung von Kuprat-Komplexen höherer Ordnung.

Country Status (7)

Country Link
US (1) US4777275A (de)
EP (1) EP0294757B1 (de)
JP (1) JP2667875B2 (de)
AT (1) ATE103924T1 (de)
CA (1) CA1311490C (de)
DE (1) DE3888872T2 (de)
ES (1) ES2062999T3 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011958A (en) * 1987-06-08 1991-04-30 G. D. Searle & Co. Process for preparing higher order cuprate complexes
US5072010A (en) * 1990-04-04 1991-12-10 University Of California Transmetalations from zirconium to copper intermediates
US5166382A (en) * 1990-04-04 1992-11-24 Regents Of The University Of California Transmetalations from zirconium to copper intermediates
US5055604A (en) * 1990-04-17 1991-10-08 G. D. Searle & Co. Process for preparing prostaglandin analogs using organozirconium compounds
US5405981A (en) * 1993-03-26 1995-04-11 The Regents Of The University Of California Copper catalyzed coupling reactions
US5684177A (en) * 1996-05-17 1997-11-04 Torcan Chemical Ltd. Misoprostol
EP0943607B1 (de) * 1996-11-14 2005-01-26 Daiichi Fine Chemical Co., Ltd. Verfahren zur herstellung von prostaglandinen
US6388128B1 (en) 1998-10-05 2002-05-14 Alcon Manufacturing, Ltd. Stannane synthesis of prostanoids
HU231185B1 (hu) * 2017-07-11 2021-07-28 CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. Eljárás Misoprostol előállítására és tisztítására

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US30287A (en) * 1860-10-09 Propelling cars on railroads
US3965143A (en) * 1974-03-26 1976-06-22 G. D. Searle & Co. 16-Oxygenated prostanoic acid derivatives
USRE30287E (en) 1974-03-26 1980-05-27 Gist-Brocades N.V. 19 Hydroxy prostaglandins
US4271314A (en) * 1979-11-28 1981-06-02 G. D. Searle & Co. 4,5-Unsaturated prostanoic acid derivatives
US4322543A (en) * 1979-11-28 1982-03-30 G. D. Searle & Co. 4,5-Unsaturated prostanoic acid derivatives
US4529812A (en) * 1983-02-02 1985-07-16 G. D. Searle & Co. 3-Oxaprostaglandins
US4543421A (en) * 1983-05-11 1985-09-24 Miles Laboratories, Inc. Conjugate addition of organocuprates generated from copper (I) cyanide and vinyl stannanes useful in prostaglandin analog synthesis
US4499296A (en) * 1983-11-14 1985-02-12 G. D. Searle & Co. Omega cycloalkyl prostaglandins
US4578505A (en) * 1984-09-04 1986-03-25 G. D. Searle & Co. Allenic prostanoic acid derivatives
US4785124A (en) * 1987-06-08 1988-11-15 G. D. Searle & Co. Process for preparing higher order cuprate complexes

Also Published As

Publication number Publication date
US4777275A (en) 1988-10-11
ATE103924T1 (de) 1994-04-15
EP0294757B1 (de) 1994-04-06
DE3888872T2 (de) 1994-08-11
JPS63316786A (ja) 1988-12-26
JP2667875B2 (ja) 1997-10-27
ES2062999T3 (es) 1995-01-01
EP0294757A3 (en) 1990-07-11
EP0294757A2 (de) 1988-12-14
CA1311490C (en) 1992-12-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee