FR2451381A1 - Procede de production d'olefines combinees a un metal - Google Patents

Procede de production d'olefines combinees a un metal

Info

Publication number
FR2451381A1
FR2451381A1 FR8005410A FR8005410A FR2451381A1 FR 2451381 A1 FR2451381 A1 FR 2451381A1 FR 8005410 A FR8005410 A FR 8005410A FR 8005410 A FR8005410 A FR 8005410A FR 2451381 A1 FR2451381 A1 FR 2451381A1
Authority
FR
France
Prior art keywords
metal
alkyl
iiib
iiia
cis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8005410A
Other languages
English (en)
Other versions
FR2451381B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2451381A1 publication Critical patent/FR2451381A1/fr
Application granted granted Critical
Publication of FR2451381B1 publication Critical patent/FR2451381B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/02—Lithium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/04—Sodium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'INVENTION CONCERNE UN PROCEDE DE PREPARATION DE COMPOSES DE FORMULES: (CF DESSIN DANS BOPI) DANS LESQUELLES R REPRESENTE F OU CL OU UN GROUPE -NRR, LES VARIABLES R ET R EGALES OU DIFFERENTES REPRESENTANT UN GROUPE ALKYLE EN C A C; X REPRESENTE UN ATOME O OU S; Z EST UN RADICAL ALKYLE EN C A C, PHENYLE OU P-METHYLPHENYLE, LE RAPPORT DE L'ISOMERE TRANS (IIIB) A L'ISOMERE CIS (IIIA) ETANT SUPERIEUR A 70:30. LE PROCEDE CONSISTE A FAIRE REAGIR DES ETHANES SUBSTITUES AVEC UN METAL-ALKYLE POUR FORMER LES OLEFINES ISOMERIQUES METALLEES (IIIA ET IIIB) AYANT LE RAPPORT TRANS:CIS DESIRE. APPLICATION A LA PRODUCTION DE PREGNANES INSATURES EN POSITION 16 UTILES DANS LA SYNTHESE DE DIVERS STEROIDES CORTICAUX ANTI-INFLAMMATOIRES.
FR8005410A 1979-03-12 1980-03-11 Procede de production d'olefines combinees a un metal Granted FR2451381A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1950979A 1979-03-12 1979-03-12

Publications (2)

Publication Number Publication Date
FR2451381A1 true FR2451381A1 (fr) 1980-10-10
FR2451381B1 FR2451381B1 (fr) 1983-04-01

Family

ID=21793590

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8005410A Granted FR2451381A1 (fr) 1979-03-12 1980-03-11 Procede de production d'olefines combinees a un metal

Country Status (8)

Country Link
JP (1) JPS56115789A (fr)
CH (1) CH643854A5 (fr)
DE (1) DE3008906A1 (fr)
FR (1) FR2451381A1 (fr)
GB (1) GB2046755B (fr)
HU (1) HU184729B (fr)
IT (1) IT1141259B (fr)
NL (1) NL187484C (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2676740A1 (fr) * 1991-05-23 1992-11-27 Roussel Uclaf Nouveaux derives sterouides du pregna-4,9(11),17(20)-trie-3-one, leur preparation, leur application a la preparation de composes sterouides de type pregna-4,9(11),16-triene-3,20-dione et nouveaux intermediaires.
FR2677029A1 (fr) * 1991-05-23 1992-12-04 Roussel Uclaf Nouveaux derives sterouides de l'andostra-4,9(11),16-trien-3-one.
FR2677028A1 (fr) * 1991-05-23 1992-12-04 Roussel Uclaf Nouveaux derives sterouides du pregna-4,9(11),17(20)-trien-3-one.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3053911A (en) * 1959-06-25 1962-09-11 Union Carbide Corp New method for the preparation of metal-halogeno-acetylides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2210010A1 (de) * 1972-03-02 1973-09-06 Dynamit Nobel Ag Verfahren zur herstellung von 2chlorvinylmethylaether

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3053911A (en) * 1959-06-25 1962-09-11 Union Carbide Corp New method for the preparation of metal-halogeno-acetylides

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EXBK/68 *
EXBK/78 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2676740A1 (fr) * 1991-05-23 1992-11-27 Roussel Uclaf Nouveaux derives sterouides du pregna-4,9(11),17(20)-trie-3-one, leur preparation, leur application a la preparation de composes sterouides de type pregna-4,9(11),16-triene-3,20-dione et nouveaux intermediaires.
FR2677029A1 (fr) * 1991-05-23 1992-12-04 Roussel Uclaf Nouveaux derives sterouides de l'andostra-4,9(11),16-trien-3-one.
FR2677028A1 (fr) * 1991-05-23 1992-12-04 Roussel Uclaf Nouveaux derives sterouides du pregna-4,9(11),17(20)-trien-3-one.
EP0515264A3 (en) * 1991-05-23 1993-01-13 Roussel-Uclaf New steroid derivatives of pregna-4,9(11),17(20)-trien-3-on, their preparation, their use in the preparation of derivatives of pregna-4,9(11),16-trien-3,20-dione and intermediates therefor

Also Published As

Publication number Publication date
JPS56115789A (en) 1981-09-11
JPS6337797B2 (fr) 1988-07-27
FR2451381B1 (fr) 1983-04-01
IT8020292A0 (it) 1980-02-29
DE3008906A1 (de) 1980-09-25
DE3008906C2 (fr) 1989-09-21
IT1141259B (it) 1986-10-01
CH643854A5 (de) 1984-06-29
GB2046755A (en) 1980-11-19
HU184729B (en) 1984-10-29
NL187484B (nl) 1991-05-16
NL8001021A (nl) 1980-09-16
GB2046755B (en) 1983-01-12
NL187484C (nl) 1991-10-16

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