DE3880991D1 - Aminoanthracendion-bis-platinkomplexe, nuetzlich als antitumor-agenzien. - Google Patents

Aminoanthracendion-bis-platinkomplexe, nuetzlich als antitumor-agenzien.

Info

Publication number
DE3880991D1
DE3880991D1 DE8888121072T DE3880991T DE3880991D1 DE 3880991 D1 DE3880991 D1 DE 3880991D1 DE 8888121072 T DE8888121072 T DE 8888121072T DE 3880991 T DE3880991 T DE 3880991T DE 3880991 D1 DE3880991 D1 DE 3880991D1
Authority
DE
Germany
Prior art keywords
aminoanthracendion
useful
antitumor agents
platinum complexes
complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888121072T
Other languages
English (en)
Other versions
DE3880991T2 (de
Inventor
Alessandro Pasini
Franco Zunino
Odoardo Tofanetti
Carmelo A Gandolfi
Sergio Tognella
Silvano Spinelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics SpA
Original Assignee
Roche Diagnostics SpA
Boehringer Mannheim Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT23094/87A external-priority patent/IT1223537B/it
Priority claimed from IT8848492A external-priority patent/IT1235045B/it
Application filed by Roche Diagnostics SpA, Boehringer Mannheim Italia SpA filed Critical Roche Diagnostics SpA
Publication of DE3880991D1 publication Critical patent/DE3880991D1/de
Application granted granted Critical
Publication of DE3880991T2 publication Critical patent/DE3880991T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE88121072T 1987-12-18 1988-12-16 Aminoanthracendion-bis-platinkomplexe, nützlich als Antitumor-Agenzien. Expired - Fee Related DE3880991T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT23094/87A IT1223537B (it) 1987-12-18 1987-12-18 Amino antracenedioni bis platino complessi utili come agenti antitumorali
IT8848492A IT1235045B (it) 1988-10-26 1988-10-26 Bis-platino complessi di amino-antracenedioni

Publications (2)

Publication Number Publication Date
DE3880991D1 true DE3880991D1 (de) 1993-06-17
DE3880991T2 DE3880991T2 (de) 1994-01-05

Family

ID=26328335

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88121072T Expired - Fee Related DE3880991T2 (de) 1987-12-18 1988-12-16 Aminoanthracendion-bis-platinkomplexe, nützlich als Antitumor-Agenzien.

Country Status (8)

Country Link
US (1) US5145848A (de)
EP (2) EP0396588A1 (de)
JP (1) JPH03503046A (de)
AU (1) AU2817589A (de)
CA (1) CA1327355C (de)
DE (1) DE3880991T2 (de)
ES (1) ES2056887T3 (de)
WO (1) WO1989005815A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770591A (en) * 1986-07-25 1998-06-23 The University Of Vermont And State Agricultural College Bis-platinum complexes as chemotherapeutic agents
US5107007A (en) * 1989-09-01 1992-04-21 The University Of Vermont And State Agricultural College Bis-platinum complexes as chemotherapeutic agents
US5380897A (en) * 1993-05-25 1995-01-10 Hoeschele; James D. Tri(platinum) complexes
US5409915A (en) * 1993-09-14 1995-04-25 The University Of Vermont And State Agricultural College Bis-platinum (IV) complexes as chemotherapeutic agents
ZA976421B (en) * 1996-07-22 1998-01-22 Boehringer Mannheim Italia New bis-platinum complexes with polyamine ligands as antitumor agents.
ZA976422B (en) * 1996-07-22 1998-01-22 Boehringer Mannheim Italia New bis-platinum complexes with polymethylene derivatives as ligands having antitumor activity.
WO2001036431A1 (en) 1999-11-15 2001-05-25 Parker Hughes Institute Diamino platinum (ii) antitumor complexes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4296030A (en) * 1980-04-09 1981-10-20 American Cyanamid Company Metal chelates of 1,4-bis(substituted-amino-5,8-dihydroxy-anthraquinones
EP0169645A1 (de) * 1984-06-27 1986-01-29 Johnson Matthey Public Limited Company Platin-Koordinationsverbindungen
IL76002A0 (en) * 1984-08-03 1985-12-31 Boehringer Biochemia Srl Amino-anthracenediones-platinum complexes useful as anti-cancer compounds

Also Published As

Publication number Publication date
EP0320960B1 (de) 1993-05-12
CA1327355C (en) 1994-03-01
US5145848A (en) 1992-09-08
WO1989005815A1 (en) 1989-06-29
DE3880991T2 (de) 1994-01-05
ES2056887T3 (es) 1994-10-16
EP0396588A1 (de) 1990-11-14
JPH03503046A (ja) 1991-07-11
AU2817589A (en) 1989-07-19
EP0320960A1 (de) 1989-06-21

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee