DE3874798D1 - Therapeutisches proteinagens in form von aerosol. - Google Patents

Therapeutisches proteinagens in form von aerosol.

Info

Publication number
DE3874798D1
DE3874798D1 DE8888303909T DE3874798T DE3874798D1 DE 3874798 D1 DE3874798 D1 DE 3874798D1 DE 8888303909 T DE8888303909 T DE 8888303909T DE 3874798 T DE3874798 T DE 3874798T DE 3874798 D1 DE3874798 D1 DE 3874798D1
Authority
DE
Germany
Prior art keywords
aerosol
therapeutic protein
protein agent
agent
paradigmatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8888303909T
Other languages
English (en)
Other versions
DE3874798T2 (de
Inventor
Nicolaas J Roosdorp
Ronald G Crystal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cooper Laboratories Inc
Original Assignee
Cooper Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cooper Laboratories Inc filed Critical Cooper Laboratories Inc
Application granted granted Critical
Publication of DE3874798D1 publication Critical patent/DE3874798D1/de
Publication of DE3874798T2 publication Critical patent/DE3874798T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
DE8888303909T 1987-04-30 1988-04-29 Therapeutisches proteinagens in form von aerosol. Expired - Lifetime DE3874798T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4444687A 1987-04-30 1987-04-30

Publications (2)

Publication Number Publication Date
DE3874798D1 true DE3874798D1 (de) 1992-10-29
DE3874798T2 DE3874798T2 (de) 1993-04-15

Family

ID=21932433

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888303909T Expired - Lifetime DE3874798T2 (de) 1987-04-30 1988-04-29 Therapeutisches proteinagens in form von aerosol.

Country Status (8)

Country Link
US (1) US5618786A (de)
EP (1) EP0289336B1 (de)
JP (1) JP2656944B2 (de)
AT (1) ATE80796T1 (de)
CA (1) CA1327309C (de)
DE (1) DE3874798T2 (de)
ES (1) ES2035920T3 (de)
GR (1) GR3006427T3 (de)

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DE4117078A1 (de) * 1991-05-25 1992-11-26 Boehringer Ingelheim Kg Verfahren zur herstellung therapeutisch anwendbarer aerosole
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US20060281681A1 (en) * 1997-05-28 2006-12-14 Pilon Aprile L Methods and compositions for the reduction of neutrophil influx and for the treatment of bronchpulmonary dysplasia, respiratory distress syndrome, chronic lung disease, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease
US20060025348A1 (en) * 1997-05-28 2006-02-02 Pilon Aprile L Methods and compositions for the treatment of fibrotic conditions & impaired lung function & to enhance lymphocyte production
US6255281B1 (en) * 1997-05-28 2001-07-03 Claragen, Inc. And U.S. Government Use of recombinant human uteroglobin in treatment of inflammatory and fibrotic conditions
US20030035778A1 (en) * 1997-07-14 2003-02-20 Robert Platz Methods and compositions for the dry powder formulation of interferon
US6565885B1 (en) * 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6309623B1 (en) * 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6660715B2 (en) * 1998-11-19 2003-12-09 Massachusetts Institute Of Technology Nonaqueous solutions and suspensions of macromolecules for pulmonary delivery
US6676930B2 (en) 1999-11-28 2004-01-13 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
US6156294A (en) 1999-11-28 2000-12-05 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
TWI290473B (en) 2000-05-10 2007-12-01 Alliance Pharma Phospholipid-based powders for drug delivery
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en) * 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US20030072717A1 (en) 2001-02-23 2003-04-17 Vapotronics, Inc. Inhalation device having an optimized air flow path
WO2003018620A2 (en) * 2001-08-27 2003-03-06 Les Laboratoires Aeterna Inc. Serine protease inhibitor and processes for the preparation thereof
US7176278B2 (en) 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
WO2003053411A1 (en) 2001-12-19 2003-07-03 Nektar Therapeutics Pulmonary delivery of aminoglycosides
WO2005014825A2 (en) * 2003-08-08 2005-02-17 Arriva Pharmaceuticals, Inc. Methods of protein production in yeast
EP1684719B1 (de) * 2003-11-14 2011-10-26 Baxter International Inc. Alpha1-antitrypsin-zusammensetzungen und behandlungsverfahren unter verwendung dieser zusammensetzungen
US7914771B2 (en) * 2004-03-09 2011-03-29 Arriva Pharmaceuticals, Inc. Treatment of chronic obstructive pulmonary disease by low dose inhalation of protease inhibitor
IL163453A0 (en) * 2004-08-10 2009-02-11 Yeda Res & Dev Enzyme inhibitor in leukemia
US20070105768A1 (en) * 2004-11-10 2007-05-10 Rajiv Nayar Dry recombinant human alpha 1-antitrypsin formulation
WO2007091266A2 (en) * 2006-02-09 2007-08-16 Kamada Ltd. Alpha-i antitrypsin for treating exacerbation episodes of pulmonary diseases
EP2077132A1 (de) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung, Aufbewahrungsvorrichtung und Verfahren zur Abgabe einer Formulierung
AU2009246543B2 (en) 2008-05-13 2015-08-06 Clarassance, Inc. Recombinant human CC10 and compositions thereof for use in the treatment of nasal rhinitis
EP2414560B1 (de) 2009-03-31 2013-10-23 Boehringer Ingelheim International GmbH Verfahren zur beschichtung einer oberfläche eines bauteils
WO2010133294A2 (de) 2009-05-18 2010-11-25 Boehringer Ingelheim International Gmbh Adapter, inhalationseinrichtung und zerstäuber
US9168285B2 (en) 2009-10-15 2015-10-27 Therabron Therapeutics, Inc. Recombinant human CC10 protein for treatment of influenza and ebola
RU2554745C2 (ru) 2009-10-15 2015-06-27 Кларассанс, Инк. Рекомбинантный человеческий белок сс10 для лечения гриппа
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US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
WO2011160932A1 (en) 2010-06-24 2011-12-29 Boehringer Ingelheim International Gmbh Nebulizer
RU2425691C1 (ru) * 2010-07-15 2011-08-10 ВАКЕ спол с.р.о. Аэрозольный препарат на основе апротинина для лечения вирусных респираторных инфекций
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
RU2657523C2 (ru) * 2011-11-03 2018-06-14 Олег Петрович Жирнов Фармацевтический аэрозольный состав ингибиторов протеаз с озон-сберегающим пропеллентом и его получение
JP2015504051A (ja) 2011-12-30 2015-02-05 グライフォルス・ス・アー 肺の増悪の発現または進行を遅延させるためのアルファ１−プロテイナーゼ阻害剤
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
PL2835146T3 (pl) 2013-08-09 2021-04-06 Boehringer Ingelheim International Gmbh Nebulizator
JP6643231B2 (ja) 2013-08-09 2020-02-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
MX2016014399A (es) 2014-05-07 2017-01-20 Boehringer Ingelheim Int Nebulizador.
ES2874029T3 (es) 2014-05-07 2021-11-04 Boehringer Ingelheim Int Nebulizador
EP3139979B1 (de) 2014-05-07 2023-07-05 Boehringer Ingelheim International GmbH Einheit, zerstäuber und verfahren
FI3723790T3 (fi) 2017-12-12 2024-04-19 Kamada Ltd Menetelmiä immuunitoleranssin indusoimiseksi ja lääkevasta-ainevasteen vähentämiseksi

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GB1454105A (en) * 1972-11-04 1976-10-27 Hoechst Ag Preparation containing luteinizing hormone-releasing factor
DE2254061A1 (de) * 1972-11-04 1974-05-16 Hoechst Ag Lh-releasing hormon zur nasalen applikation
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AU577259B2 (en) * 1982-08-13 1988-09-22 Zymogenetics Inc. Glycolytic promters for regulated protein expression protease inhibitor
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US4711848A (en) * 1984-03-14 1987-12-08 Zymogenetics, Inc. Site specific mutagenesis in alpha-1-antitrypsin
US4732973A (en) * 1984-06-14 1988-03-22 Chiron Corporation Active site modified protease α-1-antitrypsin inhibitors
DE3666826D1 (en) * 1985-01-18 1989-12-14 Searle & Co Human natural inhibitor of collagenases
EP0223831B1 (de) * 1985-05-22 1992-07-15 Liposome Technology, Inc. Verfahren und system zum einatmen von liposomen
US5093316A (en) * 1986-12-24 1992-03-03 John Lezdey Treatment of inflammation
US4916117A (en) * 1986-12-24 1990-04-10 John Lezdey Treatment of inflammation using alpha 1-antichymotrypsin
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US5215965A (en) * 1990-10-02 1993-06-01 John Lezdey Treatment of inflammation

Also Published As

Publication number Publication date
GR3006427T3 (de) 1993-06-21
ATE80796T1 (de) 1992-10-15
CA1327309C (en) 1994-03-01
EP0289336A2 (de) 1988-11-02
DE3874798T2 (de) 1993-04-15
JP2656944B2 (ja) 1997-09-24
EP0289336A3 (en) 1989-10-11
US5618786A (en) 1997-04-08
AU1532088A (en) 1988-11-03
ES2035920T3 (es) 1993-05-01
EP0289336B1 (de) 1992-09-23
AU605580B2 (en) 1991-01-17
JPS6434923A (en) 1989-02-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: COOPER LABORATORIES, MOUNTAIN VIEW, CALIF., US THE